| Test Name: |
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Ceruloplasmin
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| Test Code(s): |
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CER / XCERU
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| CPT Code(s): |
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82390
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| Methodology: |
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Nephelometry
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| Clinical Significance: |
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Serum ceruloplasmin is decreased in Wilson's disease. 10% of people heterozygous for Wilson's disease have decreased ceruloplasmin. Moderate, transient deficiencies occur in some patients with nephrosis, sprue or Kwashiorkor. Serum ceruloplasmin is increased in primary biliary cirrhosis, pregnancy, patients taking estrogen or birth control pills, thyrotoxicosis, cancer or acute inflammatory reactions.
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| Request Form: |
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UWHC Laboratory Request Form (UWH 1289220, 4004202); Write in test if not on form.
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| Days Performed: |
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Daily, 24 hours.
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| Turnaround Time: |
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Stat: 1 hour.
Routine: 4 hours.
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Specimen Requirements
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| Specimen: |
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Blood
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| Collection Container: |
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Preferred: Green cap with yellow ring (PST)
Also Acceptable:
Green top,
Red cap with yellow ring (SST),
Red top
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| Collection Volume: |
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Preferred: 1 mL
Pediatrics: 0.5 mL
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| Sample Analyzed: |
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Plasma or serum
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| Volume Required: |
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Preferred: 0.5 mL
Pediatrics: 0.1 mL
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| Specimen Processing: |
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Centrifuge within 2 hours of draw. If a complete barrier has not formed, transfer cell-free plasma/serum to clear plastic vial. Refrigerate.
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| Specimen Transport: |
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Transport specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack if coming from outreach location. Transport frozen plasma/serum aliquot on dry ice to UWHC Core Laboratory (B4/220).
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| Stability: |
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Ambient: 8 hours
Refrigerated: 7 days
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Interpretation
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Reference Interval:
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| Age: |
mg/dL |
| 0 days - 30 days |
8 - 25 |
| 1 month - 12 months |
15 - 50 |
| 13 months - 9 years |
25 - 55 |
| 10 years - 17 years |
20 - 55 |
| 18 years and up |
20 - 60 |
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