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UW Health SMPH
American Family Children's Hospital

UW Hospital and Clinics Lab Test Directory

Test Name: Ceruloplasmin

Test Code(s): CER / XCERU

CPT Code(s): 82390

Methodology: Nephelometry

Clinical Significance: Serum ceruloplasmin is decreased in Wilson's disease. 10% of people heterozygous for Wilson's disease have decreased ceruloplasmin. Moderate, transient deficiencies occur in some patients with nephrosis, sprue or Kwashiorkor. Serum ceruloplasmin is increased in primary biliary cirrhosis, pregnancy, patients taking estrogen or birth control pills, thyrotoxicosis, cancer or acute inflammatory reactions.

Request Form: UWHC Laboratory Request Form (UWH 1289220, 4004202); Write in test if not on form.

Days Performed: Daily, 24 hours.

Turnaround Time: Stat: 1 hour.
Routine: 4 hours.

Specimen Requirements

Specimen: Blood

Collection Container: Preferred: Green cap with yellow ring (PST)
Also Acceptable: Green top, Red cap with yellow ring (SST), Red top

Collection Volume: Preferred: 1 mL
Pediatrics: 0.5 mL

Sample Analyzed: Plasma or serum

Volume Required: Preferred: 0.5 mL
Pediatrics: 0.1 mL

Specimen Processing: Centrifuge within 2 hours of draw. If a complete barrier has not formed, transfer cell-free plasma/serum to clear plastic vial.  Refrigerate.

Specimen Transport: Transport specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack if coming from outreach location. Transport frozen plasma/serum aliquot on dry ice to UWHC Core Laboratory (B4/220).

Stability: Ambient: 8 hours
Refrigerated: 7 days


Reference Interval:
Age:    mg/dL
0 days - 30 days 8 - 25
1 month - 12 months 15 - 50
13 months - 9 years 25 - 55
10 years - 17 years 20 - 55
18 years and up 20 - 60




Copper Oxidase

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