UW Hospital and Clinics Lab Test Directory
| Test Name: |
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STR Engraftment Unseparated Lineages, Whole Blood
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| Test Code(s): |
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STREWB / HCSTREWB
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| CPT Code(s): |
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81267
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| Methodology: |
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PCR
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| Clinical Significance: |
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Typically used to assess proportions of donor and recipient derived nucleated cells post stem cell transplant or in cases of suspected graft-vs-host disease.
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| Days Performed: |
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Wed.
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| Turnaround Time: |
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Routine: 10 days.
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Specimen Requirements
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| Specimen: |
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Blood
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| Collection Instructions: |
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Testing requires referral screening. Referral Screening Flow Sheet may be printed from UConnect or see link in Additional Information. Contact UWHC Test Referral office at (608)262-6388 prior to collection.
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| Collection Container: |
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Preferred: Lavender top
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| Collection Volume: |
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Preferred: 4 mL
Pediatrics: 2 mL
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| Sample Analyzed: |
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Whole Blood
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| Volume Required: |
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Preferred: 2 mL
Pediatrics: 1.2 mL
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| Specimen Transport: |
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Transport specimen to laboratory.
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| Stability: |
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Ambient: 7 days
Refrigerated: 3 weeks
Frozen: Not acceptable
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Interpretation
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| >95% Donor DNA: |
Predominantly Donor |
| < 5% Donor DNA: |
Predominantly Recipient |
| 5-95% Donor DNA: |
Donor/Recipient Chimeric |
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| Additional Information: |
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Test requires pre-transplant DNA samples on file in the laboratory for recipient and donor.
The performance characteristics of this test were validated by UWHC Clinical Laboratories. The U.S. Food and Drug Administration (FDA) has not approved or cleared this test; however, FDA approval or clearance is currently not required for clinical use of this test. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. The UWHC Clinical Laboratories is authorized under Clinical Laboratory Improvement Amendments (CLIA) to perform high-complexity testing.
Referral Screening Flow Sheet
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Engraftment Chimeric studies
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