UW Hospital and Clinics Lab Test Directory
| Test Name: |
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Q Fever Ab
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| Test Code(s): |
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QFEVER / HCQFEVER
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| CPT Code(s): |
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86638 x2
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| Test Description: |
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Test Component: Quantitative total antibody IFA testing with phase 1 and phase 2 antigens.
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| Methodology: |
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Indirect Fluorescent Antibody
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| Clinical Significance: |
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Serodiagnosis of Coxiella burnetii infection.
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| Testing Site: |
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Testing will be sent to an approved reference laboratory.
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| Days Performed: |
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Once a week.
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| Turnaround Time: |
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Routine: 1 - 7 days.
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Specimen Requirements
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| Specimen: |
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Blood
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| Collection Instructions: |
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Acute and convalescent sera recommended for diagnostic testing.
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| Collection Container: |
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Preferred: Red top
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| Collection Volume: |
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Preferred: 4 mL
Pediatrics: 3 mL
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| Sample Analyzed: |
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Serum
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| Volume Required: |
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Preferred: 1 mL
Pediatrics: 0.5 mL
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| Specimen Processing: |
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Centrifuge. Transfer cell free serum to plastic vial. Refrigerate. Store at 2-8°C.
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| Specimen Transport: |
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Transport specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack if coming from outreach location.
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Interpretation
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Interpretive Guidelines:
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Diagnostically significant titer of 1:256 or greater indicates current or recent infection with this Rickettsial agent.
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| Test Limitations: |
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This test will only provide evidence of Coxiella burnetii exposure. Additional tests may be needed to rule out other causes of illness.
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| Additional Information: |
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Paired sera are necessary for a definitive serological confirmation of a Q fever infection.
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Coxiella burnetii Antibodies
C BURNETII
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