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UW Health SMPH
American Family Children's Hospital

UW Hospital and Clinics Lab Test Directory

Test Name: VDRL, CSF

Test Code(s): CSVDRL / HCCSVDRL

CPT Code(s): 86592

Test Description: Test Component:

Qualitation of non-treponemal antibody in spinal fluid. Titers will be performed on reactive specimens.


Methodology: Flocculation

Clinical Significance: This test provides serologic evidence of neurologic exposure to syphilis. VDRL-CSF is the only standardized test for neurosyphilis.

Testing Site: Testing will be sent to an approved reference laboratory.

Days Performed: Tuesdays and Fridays

Turnaround Time: Routine: 2 - 4 days.


Specimen Requirements

Specimen: Cerebrospinal fluid (CSF)

Collection Container: Preferred: Numbered specimen tube from sterile disposable lumbar puncture tray

Sample Analyzed: Cerebrospinal fluid (CSF) aliquot

Volume Required: Preferred: 3 mL
Pediatrics: 1 mL

Specimen Transport: Transport specimen to UWHC Core Laboratory (B4/220).  


Interpretation

Expected Results:

Non-reactive.

Test Limitations:

A negative result can occur in some neurosyphilis patients.

Syphilis

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