| Test Name: |
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Haptoglobin
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| Test Code(s): |
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HAPT / XHAPT
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| CPT Code(s): |
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83010
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| Methodology: |
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Nephelometry
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| Clinical Significance: |
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Haptoglobin is decreased or absent in red blood cell hemolysis, genetic absence, cirrhosis (decreased synthesis)and protein loss via the kidney, gastrointestinal tract and skin.
Haptoglobin is an acute phase reactant and increased levels are observed by 4 days after onset and may require 4 weeks to return to normal. It is increased in obstructive biliary disease, acute or subacute inflammation, steroid or androgen therapy, aplastic anemia and diabetes mellitus.
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| Request Form: |
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UWHC Laboratory Request Form (UWH 1289220, 4004202); Write in test if not on form.
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| Days Performed: |
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Daily, 24 hours.
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| Turnaround Time: |
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Stat: 1 hour.
Routine: 4 hours.
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Specimen Requirements
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| Specimen: |
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Blood
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| Collection Container: |
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Preferred: Green cap with yellow ring (PST)
Also Acceptable:
Green top,
Red cap with yellow ring (SST),
Red top
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| Collection Volume: |
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Preferred: 1 mL
Pediatrics: 0.4 mL
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| Sample Analyzed: |
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Plasma or serum
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| Volume Required: |
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Preferred: 0.5 mL
Pediatrics: 0.2 mL
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| Specimen Processing: |
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Centrifuge. If a complete barrier has not formed, transfer cell-free plasma/serum to plastic vial. Refrigerate.
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| Specimen Transport: |
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Transport specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack if coming from outreach location.
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| Unacceptable Criteria: |
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Hemolyzed specimens are not acceptable.
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| Stability: |
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Ambient: 8 hours
Refrigerated: 7 days
Frozen: 3 months
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Interpretation
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Reference Interval:
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| Age: |
mg/dL |
| 0 days-11 years |
20-165 |
| 12 years and up |
30-200 |
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