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UW Health SMPH
American Family Children's Hospital

UW Hospital and Clinics Lab Test Directory

Test Name: Haptoglobin

Test Code(s): HAPT / XHAPT

CPT Code(s): 83010

Methodology: Nephelometry

Clinical Significance: Haptoglobin is decreased or absent in red blood cell hemolysis, genetic absence, cirrhosis (decreased synthesis)and protein loss via the kidney, gastrointestinal tract and skin.

Haptoglobin is an acute phase reactant and increased levels are observed by 4 days after onset and may require 4 weeks to return to normal.  It is increased in obstructive biliary disease, acute or subacute inflammation, steroid or androgen therapy, aplastic anemia and diabetes mellitus.

Request Form: UWHC Laboratory Request Form (UWH 1289220, 4004202); Write in test if not on form.

Days Performed: Daily, 24 hours.

Turnaround Time: Stat: 1 hour.
Routine: 4 hours.

Specimen Requirements

Specimen: Blood

Collection Container: Preferred: Green cap with yellow ring (PST)
Also Acceptable: Green top, Red cap with yellow ring (SST), Red top

Collection Volume: Preferred: 1 mL
Pediatrics: 0.4 mL

Sample Analyzed: Plasma or serum

Volume Required: Preferred: 0.5 mL
Pediatrics: 0.2 mL

Specimen Processing: Centrifuge.  If a complete barrier has not formed, transfer cell-free plasma/serum to plastic vial.  Refrigerate.

Specimen Transport: Transport specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack if coming from outreach location.

Unacceptable Criteria: Hemolyzed specimens are not acceptable.

Stability: Ambient: 8 hours
Refrigerated: 7 days
Frozen: 3 months


Reference Interval:
Age:  mg/dL
0 days-11 years  20-165
12 years and up  30-200



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