| Test Name: |
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Lithium
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| Test Code(s): |
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LI
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| CPT Code(s): |
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80178
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| Methodology: |
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Colorimetric
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| Clinical Significance: |
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Manic depressive affective disorder.
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| Days Performed: |
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Daily, 24 hours.
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| Turnaround Time: |
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Stat: 1 hour.
Routine: 4 hours.
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Specimen Requirements
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| Specimen: |
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Blood
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| Collection Instructions: |
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Collect specimen for trough level prior to morning dose. This level should be collected 12 hours after the evening dose.
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| Collection Container: |
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Preferred: Red cap with yellow ring (SST)
Also Acceptable:
Red top
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| Collection Volume: |
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Preferred: 2 mL
Pediatrics: 0.5 mL
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| Sample Analyzed: |
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Serum
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| Volume Required: |
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Preferred: 1 mL
Pediatrics: 0.2 mL
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| Specimen Processing: |
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Centrifuge. If a complete barrier has not formed, transfer cell-free serum to plastic vial. Refrigerate.
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| Specimen Transport: |
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Transport specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack if coming from outreach location.
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| Unacceptable Criteria: |
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Green top tubes (with black, white or yellow-ring) are not acceptable.
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| Stability: |
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Ambient: 24 hours
Refrigerated: 7 days
Frozen: 6 months
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Interpretation
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Reference Interval:
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Therapeutic:
Age 0 days and up: 0.60-1.20 mmol/L
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| Critical Calls: |
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View
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| Additional Information: |
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Result of BELOW indicates that the result is below the method detection limit of 0.20 mmol/L. Serum lithium concentrations peak 2-4 hours after dose. Half-life is 24 hours in adults, 18 hours in adolescents, and greater than 36 hours in the elderly.
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