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UW Health SMPH
American Family Children's Hospital

UW Hospital and Clinics Lab Test Directory

Test Name: Fibrin Monomer


CPT Code(s): 85362

Methodology: Hemagglutination

Clinical Significance: Fibrin monomers, intermediate products between fibrinogen and fibrin, are produced during the proteolysis of fibrinogen by thrombin. This test is useful in the assessment of DIC in a patient.

Days Performed: Daily, 24 hours.

Turnaround Time: Stat: 1 hour.
Routine: 24 hours.

Specimen Requirements

Specimen: Blood

Collection Instructions: Fibrin monomer results are greatly affected by specimen collection procedure and technique. The venipuncture MUST be atraumatic to avoid hemolysis and contamination with tissue factors and platelets. Tube must be allowed to fill up to "fill" line located on tube.

Collection Container: Preferred: Light blue top (3.2% NaCitrate)

Collection Volume: Preferred: 3.5 mL
Pediatrics: 1.8 mL

Sample Analyzed: Plasma

Volume Required: Preferred: 1 mL
Pediatrics: 0.5 mL

Specimen Processing: Centrifuge specimen to yield platelet poor plasma (platelet count should be less than 10 K/uL). Separate plasma and transfer to plastic tube or vial.

Specimen Transport: Transport whole blood specimen at room temperature to UWHC Core Laboratory (B4/220) within 4 hours of collection. See "Specimen Processing" for instructions if transport criteria can not be met. Transport frozen plasma aliquot on dry ice to UWHC Core Laboratory (B4/220).  

Unacceptable Criteria: Hemolyzed specimens, clotted specimens, partially filled tubes and whole blood specimens greater than 4 hours old when received by the laboratory are not acceptable.

Stability: Ambient: 4 hours unspun; 2 hours if spun and opened


Expected Results:

18 years and up: Negative

Soluble Fibrin Monomer Complex

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