Skip to Content
UW Health SMPH
American Family Children's Hospital

UW Hospital and Clinics Lab Test Directory

Test Name: D-Dimer, Quantitative

Test Code(s): DDIMER / GM1332

CPT Code(s): 85379

Methodology: Immunoturbidimetry

Days Performed: Daily, 24 hours.

Turnaround Time: Stat: 1 hour.
Routine: 4 hours.


Specimen Requirements

Specimen: Blood

Collection Instructions: The venipuncture MUST be atraumatic to avoid hemolysis and contamination with tissue factors and platelets. Tube MUST be allowed to fill up to the "fill" line indicated on the tube.

If unable to collect 1.8 ml tube (pediatrics only) please call Core Coagulation Lab at 263-9617 or Special Coagulation Lab at 263-5005 for alternate tube and instructions.

Collection Container: Preferred: Light blue top (3.2% NaCitrate)

Collection Volume: Preferred: 3.5 mL
Pediatrics: 1.8 mL

Sample Analyzed: Plasma

Volume Required: Preferred: 1 mL
Pediatrics: 0.15 mL

Specimen Processing: If transport time exceeds 4 hours, centrifuge and transfer cell-free plasma to a plastic vial. Freeze plasma.

Specimen Transport: Transport whole blood specimen to UWHC Core Laboratory (B4/220) within 4 hours of collection.  Otherwise, transport frozen plasma aliquot on dry ice.

Unacceptable Criteria: Hemolyzed specimens, clotted specimens, partially filled tubes and whole blood specimens greater than 4 hours old when received by the laboratory are not acceptable.

Stability: Ambient: 8 hours
Refrigerated: Not acceptable
Frozen: 1 month


Interpretation

Reference Interval:

0.00-0.49 mcg/mL FEU

 

A D-dimer level < 0.5 mcg/mL FEU is inconsistent with venous thromboembolic disease. In a patient with a low or intermediate pretest probablility, venous thromboembolic disease can be ruled out if the D-dimer level is < 0.5 mcg/mL FEU. Elevated D-dimer levels are nonspecific and may be seen in recent surgery, acute infection, malignancy and renal disease. (Wells et al, NEJM 349:1227-30; Ginsberg et al, Ann Int Med 129:1006-11)

Additional Information:

This method is a quantitative method which replaces Fibrin Degradation Products.

Fibrin Degradation Products

Back to Lab Test Directory Index