The test detects antigen of both C. neoformans and C. gattii.
Presence of cryptococcal polysaccharide is indicative of cryptococcosis.
Rheumatoid factor in serum or Trichosporon beigelii infection may cause a false positive reaction.
NOTE: Titers performed on all positive specimens. Titers may not be available until 24 hours after initial test on first positives.
The first positive specimen per patient will be called to a health care provider. Positive tests should be confirmed by culture.
Because of the half-life of the cryptococcal antigen, retesting of positive patients should be done no more frequently than every 5 days.