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UW Health SMPH
American Family Children's Hospital

UW Hospital and Clinics Lab Test Directory

Test Name: Creatinine Clearance

Test Code(s): CCLR / HCCCLR

CPT Code(s): 82575

Test Description: Test Component:

Serum/plasma creatinine and urine creatinine from a timed collection of a period of 2 or more hours.

Methodology: Enzymatic; IDMS-traceable

Days Performed: Daily, 24 hours.

Turnaround Time: Stat: 1 hour.
Routine: 4 hours.

Specimen Requirements

Specimen: Blood and urine

Collection Instructions: Timed urine collection must be 2 hours or more.  Blood must be collected during or within 24 hrs of the urine collection's start or stop time.  No preservative necessary. For timed urine collections, collect all urine in container provided.  Add "Refrigerate" sticker to 24-hour container.

For 24-hour urine test the collection period must be within 22-26 hours.  Collection period starts after first void of the period.  It is very important to refrigerate specimen during and after the collection.  Indicate the date and time collection started and date and time collection finished.  If questions about collection process or container does not have instructions attached, call (608) 263-7060 for assistance.

Patient instructions available at Search for 24-hour urine collection or UWH#4339.

Collection Container: Preferred: Green cap with yellow ring (PST) and sterile screw cap or 24 hour urine container
Also Acceptable: Red cap with yellow ring (SST) and sterile screw cap or 24 hour urine container

Collection Volume: Preferred: 1 mL
Pediatrics: 0.4 mL

Sample Analyzed: Plasma or serum and urine aliquot

Volume Required: Preferred: 0.5 mL
Pediatrics: 0.2 mL

Specimen Processing: Urine: See Specimen Transport Instructions.

Blood: Centrifuge.  If a complete barrier has not formed, transfer cell-free serum/plasma to plastic vial.   Refrigerate.

Specimen Transport: After specimen collection is completed, transport entire specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack. If transport is delayed, keep specimen refrigerated.

Outreach Specimen Transport: For random collection, transport entire collection with coolant pack to UWHC Core Laboratory (B4/220). For timed collection, mix urine well and note volume and period.  Transport 50 mL aliquot on coolant pack to UWHC Core Laboratory (B4/220) along with volume and period information.


Reference Interval:
 Age  Male,mL/min  Female,mL/min
 0 days-5 months  40-60  40-60
 6 months-11 months  50-75  50-75
 12 months-4 years  60-100  60-100
 5-8 years  65-110  65-110
 9-12 years  70-120  70-120
 13 years and up  80-130  75-120


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