UW Hospital and Clinics Lab Test Directory
| Test Name: |
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CK-MB and Index, if indicated
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| Test Code(s): |
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MBI
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| CPT Code(s): |
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82553
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| Test Description: |
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Test Component: If a CK, Total is requested on a specimen from the same collect time, then a CK Index will be calculated and reported. If not, only the CK-MB isoenzyme will be reported.
Included In: CK, Total and CK-MB with Index, if indicated
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| Methodology: |
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Chemiluminescent Immunoassay
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| Request Form: |
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UWHC Laboratory Request Form (UWH 1289220, 4004202); Write in test if not on form.
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| Days Performed: |
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Daily, 24 hours.
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| Turnaround Time: |
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Stat: 1 hour.
Routine: 4 hours.
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Specimen Requirements
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| Specimen: |
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Blood
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| Collection Container: |
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Preferred: Green cap with yellow ring (PST)
Also Acceptable:
Green top,
Red cap with yellow ring (SST),
Red top
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| Collection Volume: |
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Preferred: 1 mL
Pediatrics: 0.4 mL
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| Sample Analyzed: |
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Plasma or serum
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| Volume Required: |
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Preferred: 0.5 mL
Pediatrics: 0.2 mL
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| Specimen Processing: |
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Centrifuge. If a complete barrier has not formed, transfer cell-free plasma/serum to plastic vial. Refrigerate.
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| Specimen Transport: |
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Transport specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack if coming from outreach location.
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| Stability: |
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Ambient: 12 hours
Refrigerated: 3 days
Frozen: 1 month
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Interpretation
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Reference Interval:
0.0 - 5.0 ng/mL
Interpretive Guidelines when used in conjunction with CK Index result:
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CKMB (ng/mL)
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Index
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| Non-Acute Myocardial Infarction |
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N/A
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| Gray Zone |
>5.0
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≤4.0
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| Acute Myocardial Infarction |
>5.0
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>4.0
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Peak values of CK-MB greater than 5.0 ng/mL AND CK-Index greater than 4.0 are highly indicative of myocardial damage. Diagnosing myocardial injury with the aid of laboratory medicine is best done using serial samples collected over the 24-36 hours following the suspected event.
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Creatine Kinase CK-MB CKMB
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