For Health Professionals: Naproxen and Risk of Heart Attack and Stroke
Naproxen - a drug considered so safe it has been sold over-the-counter for the last 10 years under the brand name Aleve® - was reported in late 2004 to cause an increase in heart attacks and strokes compared to placebo.
Data gathered from a National Institute of Health clinical trial suggests that patients taking Naproxen at a dose of 220 mg twice daily have a 50 percent greater risk of heart problems - including heart attack and stroke - than patients taking placebo.
The following information regarding these findings was prepared for physicians based on previous and current research. The UW Health Heart and Vascular Care program is offering this information to members of the extended UW clinical family to assist in their clinical practices. We have found this helpful in our clinics and pharmacies to help patients understand our recommendations for use of these pain medications.
Please feel free to print out the following recommendations for patients and use it in your practice: