Aortic Aneurysm/Dissection
The aorta is the main blood vessel that carries blood to the rest of the body. In patients with Marfan Syndrome, the walls of the aorta are weaker than normal.
Concerns and Symptoms
Mild aortic enlargement may not cause any noticeable symptoms at first. An enlarged aorta, however, may allow blood to leak back into the heart, due to aortic valve insufficiency. This can cause shortness of breath and a pounding heartbeat.- Upper back pain
- Coughing and wheezing
- Difficulty swallowing
- Swelling in the neck or arms
- Severe, stabbing pain in the center of the chest, abdomen, or back
- Decreased ability to move an arm, leg, or other part of the body
- Rapid pulse
- Sweating
- Dizziness
- Shortness of breath
For patients with Marfan Syndrome, it is extremely important to monitor the aorta for signs of progressive enlargement and/or an aneurysm. Using ultrasound, computed tomography (CT) scans or magnetic resonance imaging (MRI), surgeons can determine the size of a developing aortic aneurysm.
If the aortic diameter expands rapidly or reaches a critical size (usually about 4.5 to 5 cm), planned surgical repair is recommended. If surgery is performed early, before a rupture or dissection, hospital survival rates are much higher. In addition, performing surgery early increases long-term life expectancy, because there are fewer residual complications associated with aortic dissection (false lumen).
However, if an aneurysm ruptures or a dissection tears, it can cause life-threatening internal bleeding. Even with emergency surgery, the risk of mortality is up to 10 times higher.











