Sorafenib for the Treatment of Cancer
Sorafenib is an oral chemotherapy medicine given to treat cancer. It is a “targeted agent” that reduces the blood supply of the tumor and slows tumor growth.
How It Is Given
This medicine is a pill that you swallow.
Common Side Effects
- Hand and foot skin reaction – redness, pain, swelling, or blisters of the palms of the hands and soles of the feet
- Rash, redness, or itching of skin
- Frequent or loose bowel movements
- Loss of appetite
- Nausea
- Fatigue
- High blood pressure
- Allergic reaction
Less Common Side Effects
- Heart problems
- Bleeding problems – sorafenib may increase your risk of bleeding
- Hair thinning
- Mouth sores
- Weakness
- Swelling in legs
When to Call Your Health Care Provider
- Severe or constant diarrhea, nausea, vomiting not controlled by medicine
- Bleeding
- Chest pain or shortness of breath
- Fatigue so severe you cannot do your normal daily routine
Special Concerns
Sorafenib can interact with other medicines and cause serious side effects. Make sure that your cancer doctor knows all the medicines you are taking, prescribed and over-the-counter, as well as any herbal supplements. Be sure to tell your cancer doctor if you are taking the blood thinner warfarin (Coumadin®).
The information provided should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Any duplication or distribution of the information contained herein is strictly prohibited.
Last Updated: 09/23/2011
Copyright © 09/23/2011 University of Wisconsin Hospitals and Clinics Authority. All rights reserved. Produced by the Department of Nursing. HF#6676
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