ICU Sedation: Quetiapine
What is quetiapine?
Quetiapine (Seroquel® ) works in the brain to cause sedation (sleepiness, drowsiness) and decrease agitation. It has a calming effect and makes the patient feel more comfortable.
Why is quetiapine important?
Patients in an intensive care unit, especially ones who require a breathing machine (mechanical ventilator) to help their breathing, may be agitated and
uncomfortable. Quetiapine can help decrease the patient’s agitation. Patients
in the intensive care unit also may have difficulty sleeping. Quetiapine can increase sleep quality.
How will the patient look or feel on
The patient will look very relaxed and may look like they are sleeping. Depending on the amount of quetiapine needed, the patient may or may not be able to open their eyes or respond to questions. The patient will feel calm and less anxious.
What are the side effects of quetiapine?
Quetiapine can cause dry mouth, constipation, dizziness and may cause a decrease in blood pressure. Rarely, quetiapine can cause abnormal heart rhythms. In some patients, this medication may cause abnormal movements of their arms, legs or heads which will go away when the medication is stopped.
How long will quetiapine be continued?
The length of time the patient requires quetiapine will depend on their medical condition. The medical staff will regularly evaluate if the quetiapine is still needed.
If you have questions about quetiapine or other questions relating to the patient’s care, please ask the staff in the intensive care unit.
The information provided should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Any duplication or distribution of the information contained herein is strictly prohibited.
Last Updated: 05/19/2010
Copyright © 05/07/2010 University of Wisconsin Hospitals and Clinics Authority. All rights reserved. Produced by the Department of Nursing. HF#7028
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