Medications and Herbs Which Affect Bleeding
Many drugs, herbs, vitamins and diet supplements may increase bleeding during and after a test or surgery. Below is a list of the more common agents that may cause bleeding. This list may not include every drug. You should always contact your doctor’s office if you are not sure whether a drug is safe to take.
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Anti-platelet Agents |
Anticoagulants |
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Anagrelide (Agrylin®) |
Dipyridamole/aspirin (Aggrenox®) |
Anisindione (Miradon®) |
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Aspirin (any brand, all doses) |
Enteric coated aspirin (Ecotrin®) |
Enoxaparin (Lovenox®) injection |
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Cilostazol (Pletal®) |
Ticlopidine (Ticlid®) |
Heparin injection |
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Clopidogrel (Plavix®) |
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Pentosan polysulfate (Elmiron®) |
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Dipyradamole (Persantine®) |
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Warfarin (Coumadin®) |
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Non-steroidal anti-inflammatory drugs |
Herbs/ vitamins |
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Diclofenac (Voltaren®, Cataflam®) |
Tolmetin (Tolectin®) |
Ajoene |
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Diflunisal (Dolobid®) |
Trilisate (Salicylate combination) |
Birch bark |
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Etodolac (Lodine®) |
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Cayenne |
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Fenoprofen (Nalfon®) |
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Chinese black tree fungus |
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Flurbiprogen (Ansaid®) |
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Cumin |
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Ibuprofen (Motrin®, Advil®, Nuprin®, Rufen®) |
Evening primrose oil |
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Indomethacin (Indocin®) |
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Feverfew |
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Ketoprofen (Orudis®, Actron®) |
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Garlic |
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Ketorlac (Toradol®) |
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Ginger |
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Meclofenamate (Meclomen®) |
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Ginkgo biloba |
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Meloxican (Mobic®) |
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Ginseng |
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Nabumeton (Relafen®) |
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Grapeseed extract |
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Naproxen (Naprosyn®, Naprelan®, Aleve®) |
Milk thistle |
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Oxaprozin (Daypro®) |
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Omega 3 fatty acids |
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Piroxicam (Feldene®) |
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Onion extract |
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Salsalate (Salflex®, Disalcid®) |
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St. John’s wort |
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Sulindac (Clinoril®) |
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Tumeric |
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Sulfinpyrazone |
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Vitamins C & E |
Before a Test or Surgery
- Stop taking all vitamins, herbs and diet supplements, for 10-14 days before and up to 7 days after your test or surgery.
- Stop taking all anti-platelet drugs, non-steroidal anti-inflammatory drugs and aspirin, 7 days before and for 7 days after your test or surgery.
- Stop taking Coumadin 5 days before your surgery. Do not restart this drug until told to do so by your doctor.
The information provided should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Any duplication or distribution of the information contained herein is strictly prohibited.
Last Updated: 06/20/2011
Copyright © 06/20/2011 University of Wisconsin Hospitals and Clinics Authority. All rights reserved. Produced by the Department of Nursing. UWH #6404
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