Stereotactic Core Breast Biopsy
Based on the results of your last mammogram, a doctor (radiologist) has recommended a stereotactic core breast biopsy. This doctor removes small samples of tissue from the breast using a needle. The doctor guides the needle to the correct place using a special mammography machine. Most of these breast biopsies (about 80%) done at the UW Breast Center turn out to be benign (not cancer).
Advantages of Stereotactic Core Breast Biopsy
- It can be performed on very small lesions.
- It can be done on deposits of calcium (calcifications). These occur naturally as breast tissue changes and ages. At times, the size, number, shape, and pattern of calcifications can raise concern.
A Breast Center nurse will review all your prescribed and over-the-counter medicines. You will need to stop any blood thinners 5 days before the biopsy. These include:
- Aspirin (Ecotrin® Excedrin®, Alka-seltzer®, Anacin®, etc.)
- Non-steroidal anti-inflammatory drugs (ibuprofen, Advil®, Motrin®, Aleve®, Nuprin® naproxen, Naprosyn®, etc.)
- Vitamin E, herbal medicines or teas
- Warfarin or Coumadin® - We will work with your doctor to stop these.
If you would like a medicine to help you relax during the biopsy, ask your doctor for this. This must be arranged in advance. If you decide to take it, you must have someone drive you home. Take it as prescribed. The Breast Center does not provide these medicines. Bring the medicine container with you on the day of your biopsy.
Let us know of any allergies. This includes; lidocaine or any other medicines, metal, or tape.
On the day of the biopsy, eat only a light meal since you will lie on your stomach.
Wear a two-piece outfit. You will undress from the waist up.
Do not wear talcum powder or deodorant.
Plan on being at the Breast Center for about 2 hours.
During the Biopsy
You will lie face down on a special table. The table will be raised so the doctor can work from under it. Your breast will be placed through a round opening in the table. Your breast will be held in place by a slight compression with paddles.
A staff member will be standing near you to give you guidance and support.

Mammograms will be taken from beneath the table. This will help to locate the correct site for biopsy. Your breast will be numbed with lidocaine. You will feel a sting, but you should not feel any pain after this is given. Let the staff know if you are having any pain.
Once your breast is numb, a small nick will be made in the skin of your breast to place the needle. You may feel pressure as this needle is placed, but should not feel any pain.
You will hear a whirring sound from the biopsy machine as samples are being taken. Several “cores” of tissue are taken. The samples will be sent to pathology.
After the biopsy, a small titanium clip is placed in the breast. It is used as a marker. It will be seen on future mammograms. There are no known risks with having a clip.
The needle will be removed from your breast. There may be slight bleeding. Pressure will be applied until it stops. The site will be covered with thin strips of tape (Steri-strips), and a cold pack will be placed. You will be asked to sit for 10-15 minutes to make sure there are no problems with the site.
A final mammogram will be performed to ensure the biopsy went as planned.
Care after the biopsy
Keep the bandage in place for 24 hours. The Steri-strips will loosen and come off on their own in about 7-10 days. If they are still in place after 7 days you may gently peel them off.
You will be given a cold pack to reduce the swelling and help with pain. Use a cold pack or ice 3 times for 15-20 minutes for the rest of the day.
You may take Tylenol® every 4-6 hours as needed for pain, (unless you have liver disease).
You may shower after 24 hours.
Mild bruising can occur, but should go away in 5-7 days
For the first 24 hours, wear a bra for support and avoid vigorous arm movements and heavy lifting. If you wish, you may return to work and most activities the next day.
If you notice any excess swelling, bleeding, drainage, redness, or heat, please call your doctor or Breast Center nurse.
The final results of the test should be available in about 3-4 working days. The doctor who ordered the exam will provide you with the results.
Phone Numbers
If you have further questions or concerns:
Breast Center, Monday through Friday, 8:00 a.m. to 5:00 p.m: (608) 266-6400
Breast Care Coordinator (608) 266-6094
After hours and weekends, call (608) 262-0486. This will give you the paging operator. Ask to speak to the radiologist on call. Give the operator your name and phone number with the area code. The doctor will call you back.
If you live out of the area, call 1-800-323-8942.
More Instructions
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Spanish version Health Facts for You #5990
The information provided should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Any duplication or distribution of the information contained herein is strictly prohibited.
Last Updated: 11/19/2008
Copyright © 11/19/2008 University of Wisconsin Hospitals and Clinics Authority. All rights reserved. Produced by the Department of Nursing. UWH #5707
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