Diabetes: Differences Between Type 1 and 2
In general, people with diabetes either have a total lack of insulin (type 1 diabetes) or they have too little insulin or cannot use insulin effectively (type 2 diabetes).
- Type 1 diabetes (formerly called juvenile-onset or insulin-dependent diabetes), accounts for 5 to 10 out of 100 people who have diabetes. In type 1 diabetes, the body's immune system destroys the cells that release insulin, eventually eliminating insulin production from the body. Without insulin, cells cannot absorb sugar (glucose), which they need to produce energy.
- Type 2 diabetes (formerly called adult-onset or non–insulin-dependent diabetes) can develop at any age. It most commonly becomes apparent during adulthood. But type 2 diabetes in children is rising. Type 2 diabetes accounts for the vast majority of people who have diabetes—90 to 95 out of 100 people. In type 2 diabetes, the body isn't able to use insulin the right way. This is called insulin resistance. As type 2 diabetes gets worse, the pancreas may make less and less insulin. This is called insulin deficiency.
How are these diseases different?
|Type 1 diabetes||Type 2 diabetes|
|Symptoms usually start in childhood or young adulthood. People often seek medical help, because they are seriously ill from sudden symptoms of high blood sugar.||The person may not have symptoms before diagnosis. Usually the disease is discovered in adulthood, but an increasing number of children are being diagnosed with the disease.|
|Episodes of low blood sugar level (hypoglycemia) are common.||There are no episodes of low blood sugar level, unless the person is taking insulin or certain diabetes medicines.|
|It cannot be prevented.||It can be prevented or delayed with a healthy lifestyle, including maintaining a healthy weight, eating sensibly, and exercising regularly.|
How are they alike?
Both types of diabetes greatly increase a person's risk for a range of serious complications. Although monitoring and managing the disease can prevent complications, diabetes remains the leading cause of blindness and kidney failure. It also continues to be a critical risk factor for heart disease, stroke, and foot or leg amputations.
|E. Gregory Thompson, MD - Internal Medicine|
|David C.W. Lau, MD, PhD, FRCPC - Endocrinology|
|Last Revised||July 16, 2013|
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