Polymorphous Low-Grade Adenocarcinoma
National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Polymorphous Low-Grade Adenocarcinoma is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Synonyms Back to top
- Lobular Carcinoma of the Minor Salivary Glands
- Low-Grade Papillary Carcinoma of the Palate
- Pleomorphic Adenoma
- Terminal Duct Carcinoma
Disorder Subdivisions Back to top
General Discussion Back to top
Polymorphous low-grade adenocarcinoma (PLGA) is a rare tumor of the salivary glands that is limited, to a great extent, to the minor salivary glands and commonly, but not exclusively, localized in the palate of the mouth. The major salivary glands are the parotid glands (at the side of the face, below the ears), the sublingual glands (below the tongue), and the submandibular glands (below the lower jaw). As the name suggests, each of the major salivary glands is of substantial size and visible to the naked eye. There are about 600 to 1,000 minor salivary glands that are microscopic in size. These minor salivary glands are found in the lining (mucosa) of the lips, tongue, and hard and soft palate, as well as inside the nose, cheeks, and sinuses.
Less than one (1%) per cent of all cancers reported in the USA are salivary cancers and, of these, 80% begin in the parotid glands, and about 15% begin in the submandibular glands, leaving only 5% that begin in the sublingual and minor salivary glands. Most of the tumors that start in the major salivary glands turn out to be benign, while most, but not all, of the cancers that start in the minor salivary glands turn out to be malignant.
Resources Back to top
Let's Face It
School of Dentistry / Dentistry Library
1011 N. University
Concord, MA 01742
American Cancer Society, Inc.
1599 Clifton Road NE
Atlanta, GA 30329
National Cancer Institute
6116 Executive Blvd
Bethesda, MD 20892-8322
Support for People with Oral and Head and Neck Cancer, Inc.
P.O. Box 53
Locust Valley, NY 11560-0053
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Friends of Cancer Research
1800 M Street NW
Suite 1050 South
Washington, DC 22202
Cancer Support Community
1050 17th St NW
Washington, DC 20036
Lance Armstrong Foundation
2201 E. Sixth Street
Austin, TX 78702
For a Complete Report Back to top
This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email email@example.com
Last Updated: 8/7/2007
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