National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Rasmussen Encephalitis is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
- Rasmussen syndrome (RE)
- chronic encephalitis and epilepsy
- chronic localized (focal) encephalitis
- epilepsy, hemiplegia and intellectual disabilities
Rasmussen encephalitis, sometimes referred to as Rasmussen syndrome, is a rare disorder of the central nervous system characterized by chronic inflammation (encephalitis) of one hemisphere of the brain. As a result, the patient experiences frequent episodes of uncontrolled electrical disturbances in the brain that cause epileptic seizures (epilepsy). Further symptoms may include progressive weakness of one side of the body (hemiparesis), language problems (if on the left side of the brain) and intellectual disabilities. The exact cause of this disorder is not known. The two leading ideas are that the brain inflammation might be a reaction of a foreign antigen (infection) or an autoimmune disease limited to one side of the brain resulting in brain damage.
It occurs mostly, but not always, in children between the ages of two and ten years, and in many cases the course of the disease is most severe during the first 8 to 12 months. After the peak inflammatory response is reached, the progression of this disorder appears to slow or stop and the patient is left with permanent neurological deficits.
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NIH/National Institute of Neurological Disorders and Stroke
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Rasmussen's Syndrome and Hemispherectomy Support Network
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RE Children's Project, LLC
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
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Last Updated: 11/27/2012
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