Progressive Myoclonus Epilepsy
National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Progressive Myoclonus Epilepsy is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
- Myoclonic Epilepsy
- Myoclonic Progressive Familial Epilepsy
- Myoclonus Epilepsy
- Progressive Familial Myoclonic Epilepsy
- Epilepsy, Myoclonic Progressive Familial
- Myoclonic Epilepsy, Hartung Type
- Lafora Disease, Included
- Baltic Myoclonus Epilepsy
- Lafora Body Disease
- Unverricht Disease
- Unverricht-Lundborg Disease
- Lundborg-Unverricht Disease, Included
Progressive myoclonus epilepsy (PME) is a group of conditions involving the central nervous system and representing more than a dozen different diseases. These diseases share certain features, including a worsening of symptoms over time and the presence of both muscle contractions (myoclonus) and seizures (epilepsy). Patients may have more than one type of seizure, such as petit mal or grand mal. PME is progressive, but the rate of progression may be quick or slow, depending on the underlying disease.
Progressive myoclonus epilepsy (PME) is different from myoclonic epilepsy. In myoclonic epilepsy, the myoclonic jerking motions occur as part of the seizure. In PME, myoclonus occurs separately from seizures, the two respond differently to the same drugs, they evolve differently during the natural history of the disease, and they cause different problems for the patient. Some drugs that are good for seizures, e.g. phenytoin and carbamazepine, may tend to make the myoclonus worse.
8301 Professional Place
Landover, MD 20785-7223
NIH/National Institute of Neurological Disorders and Stroke
P.O. Box 5801
Bethesda, MD 20824
National Pediatric Myoclonus Center
P.O. Box 19643
Springfield, IL 62794-9643
2900 John St., Suite 402
Ontario, L3R 5G3
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
PO Box 241956
Los Angeles, CA 90024
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
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Last Updated: 1/29/2008
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