Central Diabetes Insipidus
National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Central Diabetes Insipidus is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
- neurohypophyseal diabetes insipidus
- vasopressin-sensitive diabetes insipidus
- neurogenic diabetes insipidus
Central diabetes insipidus (CDI) is a rare disorder characterized by excessive thirst (polydipsia) and excessive urination (polyuria). It is not related to the more common diabetes mellitus (sugar diabetes), in which the body does not produce or properly use insulin. CDI is a distinct disorder caused by complete or partial deficiency of the protein, arginine vasopressin (AVP), which is required by the kidneys to manage water balance in the body. If affected individuals do not have access to water, dehydration may occur. Eventually, more serious symptoms can develop including changes in consciousness and confusion associated with dehydration and elevation in serum sodium concentration (hypertonic dehydration). CDI may be caused by any condition that affects the creation, transport or release of vasopressin. CDI may be inherited or acquired. In some cases, no cause can be identified (idiopathic).
American Diabetes Association
1701 N. Beauregard Street
Alexandria, VA 22311
NIH/National Institute of Diabetes, Digestive & Kidney Diseases
Office of Communications & Public Liaison
Bldg 31, Rm 9A06
31 Center Drive, MSC 2560
Bethesda, MD 20892-2560
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
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This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
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Last Updated: 9/5/2012
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