National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Kleine-Levin Syndrome is not the name you expected.
Kleine-Levin syndrome is a rare disorder characterized by the need for excessive amounts of sleep (hypersomnolence), (i.e., up to 20 hours a day); excessive food intake (compulsive hyperphagia); and behavioral changes such as an abnormally uninhibited sexual drive. The disorder primarily affects adolescent males. When awake, affected individuals may exhibit irritability, lack of energy (lethargy), and/or lack of emotions (apathy). They may also appear confused (disoriented) and experience hallucinations. Symptoms of Kleine-Levin syndrome are cyclical. An affected individual may go for weeks or months without experiencing symptoms. When present, symptoms may persist for days to weeks. In some cases, the symptoms associated with Kleine-Levin syndrome eventually disappear with advancing age. However, episodes may recur later during life.
The exact cause of Kleine-Levin syndrome is not known. However, researchers believe that in some cases, hereditary factors may cause some individuals to have a genetic predisposition to developing the disorder. It is thought that symptoms of Kleine-Levin syndrome may be related to malfunction of the portion of the brain that helps to regulate functions such as sleep, appetite, and body temperature (hypothalamus). Some researchers speculate that Kleine-Levin syndrome may be an autoimmune disorder.
American Sleep Association
- 1002 Lititz Pike #229
- Lititz, PA 17543
- Email: firstname.lastname@example.org
- Website: http://www.sleepassociation.org/
Genetic and Rare Diseases (GARD) Information Center
- PO Box 8126
- Gaithersburg, MD 20898-8126
- Tel: (301)251-4925
- Fax: (301)251-4911
- Tel: (888)205-2311
- Website: http://rarediseases.info.nih.gov/GARD/
Kleine-Levin Syndrome Foundation
- PO Box 5382
- San Jose, CA 95150-5382
- Tel: (408)265-1099
- Fax: (408)269-2131
- Email: email@example.com
- Website: http://www.klsfoundation.org
Mental Health America
- 2000 N. Beauregard Street, 6th Floor
- Alexandria, VA 22314-2971
- Tel: (703)684-7722
- Fax: (703)684-5968
- Tel: (800)969-6642
- Email: firstname.lastname@example.org
- Website: http://www.mentalhealthamerica.net/
NIH/National Institute of Mental Health
- Health Science Writing, Press and Dissemination Branch
- 6001 Executive Boulevard
- Bethesda, MD 20892-9663
- Tel: (301)443-4513
- Fax: (301)443-4279
- Tel: (866)615-6464
- Email: email@example.com
- Website: http://www.nimh.nih.gov/index.shtml
NIH/National Institute of Neurological Disorders and Stroke
- P.O. Box 5801
- Bethesda, MD 20824
- Tel: (301)496-5751
- Fax: (301)402-2186
- Tel: (800)352-9424
- Website: http://www.ninds.nih.gov/
National Mental Health Consumers' Self-Help Clearinghouse
- 1211 Chestnut Street
- Suite 1207
- Philadelphia, PA 19107-6312
- Tel: (215)751-1810
- Fax: (215)636-6312
- Tel: (800)553-4539
- Email: firstname.lastname@example.org
- Website: http://www.mhselfhelp.org
National Sleep Foundation
- 1010 N. Glebe Road
- Suite 310
- Arlington, VA 22201
- Tel: (703)243-1697
- Email: email@example.com
- Website: http://www.sleepfoundation.org
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
Last Updated: 4/6/2007
Copyright 2007 National Organization for Rare Disorders, Inc.
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