Sutton Disease II

National Organization for Rare Disorders, Inc.

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It is possible that the main title of the report Sutton Disease II is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.


  • Aphthous Stomatitis, Recurrent
  • Aphthous Ulcer, Recurrent
  • Major Aphthous Ulcer
  • Major Canker Sore
  • Major Ulcerative Stomatitis
  • Periadenitis Mucosa Necrotica, Recurrent Type II
  • RAU
  • Recurrent Scarring Aphthae
  • von Mikulicz's Aphthae
  • Von Zahorsky's Disease

Disorder Subdivisions

  • None

General Discussion

Sutton disease II is characterized by the recurring eruption of painful inflamed ulcers in the mouth (stomatitis). There may be multiple ulcers of varying sizes. These ulcers in the mouth are commonly called canker sores. Sutton disease II is also known as recurrent aphthous stomatitis. The exact cause of this disease is not fully understood, although it may be due to an abnormal immune response to the bacteria that are normally in the mouth.


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For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

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Last Updated:  4/15/2008
Copyright  1986, 1994, 2003 National Organization for Rare Disorders, Inc.