National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Eosinophilia-Myalgia Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Eosinophilia-myalgia syndrome is a rare disorder that affects multiple organ systems of the body including the muscles, skin, and lungs. The onset of the disorder is often abrupt and the specific symptoms can vary greatly from one person to another. Common symptoms include muscle pain (myalgia), muscle weakness, cramping, skin rashes, difficulty breathing (dyspnea) and fatigue. Affected individuals have elevated levels of certain white blood cells known as eosinophils in the various tissues of the body, a condition known as eosinophilia. Eosinophilia-myalgia syndrome can potentially cause severe, disabling complications and even death.
The eosinophilia-myalgia syndrome occurred as an epidemic in 1989 and occurrence of the syndrome was traced to L-tryptophan produced by one Japanese company, Showa Denko KK. Most individuals who developed eosinophilia-myalgia syndrome had ingested contaminated L-tryptophan, a dietary amino acid supplement often sold in health food stores before being pulled from the market in 1990. However, contaminated L-tryptophan does not account for all cases of eosinophilia-myalgia syndrome suggesting that other environmental agents may cause the disorder. Very few cases of EMS have been identified since the 1989 epidemic.
Centers for Disease Control and Prevention
1600 Clifton Road NE
Atlanta, GA 30333
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
One AMS Circle
Bethesda, MD 20892-3675
National Eosinophilia Myalgia Syndrome Network, Inc.
767 Tower Boulevard
Lorain, OH 44052-5213
Email: firstname.lastname@example.org; email@example.com
Campaign Urging Research for Eosinophilic Disease (CURED)
PO Box 32
Lincolnshire, IL 60069
American Partnership for Eosinophilic Disorders
PO Box 29545
Atlanta, GA 30359
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This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
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Last Updated: 10/11/2011
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