Ring Chromosome 4
National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Ring Chromosome 4 is not the name you expected.
Ring chromosome 4 is a rare disorder that is typically characterized by loss (deletion) of genetic material from both ends of the 4th chromosome and joining of the chromosomal ends to form a ring. Associated symptoms and findings may vary greatly, depending on the location of lost genetic material and/or other factors. Some affected infants may have a low birth weight; growth retardation; delays in the acquisition of skills requiring the coordination of mental and physical activities (psychomotor retardation); an abnormally small head (microcephaly); a broad, "beaked" nose; and/or various additional physical abnormalities that are present at birth (congenital anomalies). However, cases have also been reported in which ring chromosome 4 is primarily associated with growth retardation, with no major physical anomalies and normal psychomotor development. Ring chromosome 4 is usually caused by spontaneous (de novo) errors very early in the development of the embryo that appear to occur randomly for unknown reasons (sporadically).
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- Las Vegas, NV 89136
- Tel: (702)769-9264
- Fax: (702)341-5351
- Tel: (888)486-1209
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- Website: http://www.ameriface.org
Children's Craniofacial Association
- 13140 Coit Road
- Suite 517
- Dallas, TX 75240
- Tel: (214)570-9099
- Fax: (214)570-8811
- Tel: (800)535-3643
- Email: contactCCA@ccakids.com
- Website: http://www.ccakids.com
Chromosome Disorder Outreach, Inc.
- P.O. Box 724
- Boca Raton, FL 33429-0724
- Tel: (561)395-4252
- Fax: (561)395-4252
- Email: firstname.lastname@example.org
- Website: http://www.chromodisorder.org/
Craniofacial Foundation of America
- 975 East Third Street
- Chattanooga, TN 37403
- Tel: (423)778-9176
- Fax: (423)778-8172
- Tel: (800)418-3223
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- Website: http://www.craniofacialfoundation.org/www
Genetic and Rare Diseases (GARD) Information Center
- PO Box 8126
- Gaithersburg, MD 20898-8126
- Tel: (301)251-4925
- Fax: (301)251-4911
- Tel: (888)205-2311
- Website: http://rarediseases.info.nih.gov/GARD/
March of Dimes
- 1275 Mamaroneck Avenue
- White Plains, NY 10605
- Tel: (914)997-4488
- Fax: (914)997-4763
- Email: AskUs@marchofdimes.org or firstname.lastname@example.org
- Website: http://www.marchofdimes.org and nacersano.org
NIH/National Kidney and Urologic Diseases Information Clearinghouse
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- Bethesda, MD 20892-3580
- Fax: (703)738-4929
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- Website: http://www.kidney.niddk.nih.gov/
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- Fax: (202)534-3731
- Tel: (800)433-5255
- Email: firstname.lastname@example.org
- Website: http://www.thearc.org
UNIQUE - Rare Chromosome Disorder Support Group
- G1 The Stables
- Station Road West
- Oxted, RH8 9EE
- United Kingdom
- Tel: 0044 (0)1883 723356
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- Website: http://www.rarechromo.org/html/home.asp
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
Last Updated: 9/11/2014
Copyright 2014 National Organization for Rare Disorders, Inc.
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