National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Henoch-Schönlein Purpura is not the name you expected.
Henoch-Schönlein purpura (HSP) is a rare inflammatory disease of the small blood vessels (capillaries) and is usually a self-limited disease. It is the most common form of childhood vascular inflammation (vasculitis) and results in inflammatory changes in the small blood vessels. The symptoms of HSP usually begin suddenly and may include headache, fever, loss of appetite, cramping, abdominal pain, painful menstruation, hives, bloody diarrhea, and joint pain. Red or purple spots typically appear on the skin (petechiae). Inflammatory changes associated with HSP can also develop in the joints, kidneys, digestive system, and, in rare cases, the brain and spinal cord (central nervous system).
In one form of the disorder, termed Schönlein's purpura, the skin and joints are affected but the gastrointestinal tract is not. In another form, known as Henoch's purpura, affected individuals have purplish spots on the skin and acute abdominal problems, such as glomerulonephritis (a type of kidney disorder). People with Henoch's purpura are not affected by joint disease.
The exact cause of HSP is not fully understood, although research demonstrates that it is related to an abnormal response by the immune system or, in some rare cases, an extreme allergic reaction to certain offending substances (e.g., foods or drugs).
American Autoimmune & Related Diseases
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American Kidney Fund, Inc.
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- Website: http://www.kidneyfund.org
Genetic and Rare Diseases (GARD) Information Center
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- Website: http://rarediseases.info.nih.gov/GARD/
Kidney & Urology Foundation of America, Inc.
- 104 West 40th Street
- Suite 500
- New York, NY 10018
- Tel: (212)629-9770
- Fax: (212)629-5652
- Tel: (800)633-6628
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- Website: http://www.kidneyurology.org
NIH/National Heart, Lung and Blood Institute
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NIH/National Institute of Allergy and Infectious Diseases
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National Kidney Foundation
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Platelet Disorder Support Association
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- Kansas City, MO 64188
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- Website: http://www.vasculitisfoundation.org
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
Last Updated: 10/21/2015
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