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pravastatin

Pronunciation: PRAV a STAT in

Brand: Pravachol

Pravachol 10 mg

square, pink, imprinted with PRAVACHOL 10, LOGO P

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Pravachol 20 mg

square, yellow, imprinted with PRAVACHOL 20, LOGO P

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Pravachol 40 mg

square, green, imprinted with PRAVACHOL 40, LOGO P

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Pravachol 80 mg

oval, yellow, imprinted with BMS, 80

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Pravastatin 10 mg-APO

round, pink, imprinted with APO, PRA 10

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Pravastatin 10 mg-TEV

round, pink, imprinted with 771, TEVA, 93

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Pravastatin 20 mg-APO

round, yellow, imprinted with APO, PRA 20

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Pravastatin 20 mg-MYL

square, white, imprinted with PR 20, G

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Pravastatin 20 mg-TEV

round, yellow, imprinted with TEVA, 7201

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Pravastatin 40 mg-APO

round, green, imprinted with APO, PRA 40

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Pravastatin 40 mg-MYL

square, white, imprinted with PR 40, G

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Pravastatin 40 mg-TEV

round, green, imprinted with 93, 7202, TEVA

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Pravastatin 80 mg-APO

round, yellow, imprinted with APO, PRA 80

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Pravastatin 80 mg-COB

oval, white, imprinted with LOGO, PV 80

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Pravastatin 80 mg-MYL

oval, white, imprinted with PR80, G

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Pravastatin 80 mg-TEV

oval, white, imprinted with 7270, TEVA

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What is the most important information I should know about pravastatin?

Multum donot

You should not take pravastatin if you are allergic to it, if you are pregnant or breast-feeding, or if you have liver disease.

Multum nopreg

Stop taking this medication and tell your doctor right away if you become pregnant.

Before taking pravastatin, tell your doctor if you have ever had liver or kidney disease, diabetes, or a thyroid disorder, or if you drink more than 2 alcoholic beverages daily.

Multum emt

In rare cases, pravastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Avoid eating foods that are high in fat or cholesterol. Pravastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Multum noalcohol

Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.

There are many other drugs that can increase your risk of serious medical problems if you take them together with pravastatin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Pravastatin is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

What is pravastatin?

Pravastatin is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Pravastatin reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).

Pravastatin is used to lower cholesterol and triglycerides (types of fat) in the blood.

Pravastatin is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors

Pravastatin is used in adults and children who are at least 8 years old.

Pravastatin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking pravastatin?

Multum donot

You should not take pravastatin if you are allergic to it, if you are pregnant or breast-feeding, or if you have liver disease.

To make sure you can safely take pravastatin, tell your doctor if you have any of these other conditions:

  • history of liver disease;
  • history of kidney disease;
  • diabetes;
  • a thyroid disorder; or
  • if you drink more than 2 alcoholic beverages daily.
Multum emt

In rare cases, pravastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

Tell your doctor about all other medications you use. Certain other drugs can increase your risk of serious muscle problems, and it is very important that your doctor knows if you are using any of them:

  • gemfibrozil (Lopid), fenofibric acid (Fibricor, Trilipix), or fenofibrate (Antara, Fenoglide, Lipofen, Lofibra, Tricor, Triglide);
  • medicines that contain niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others); or
  • drugs that weaken your immune system, such as steroids, cancer medicine, or medicines used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf).
Multum nopreg

FDA pregnancy category X. This medication can harm an unborn baby or cause birth defects. Do not take pravastatin if you are pregnant. Stop taking this medication and tell your doctor right away if you become pregnant. Use effective birth control to avoid pregnancy while you are taking pravastatin.

Multum nobrfeed

Pravastatin may pass into breast milk and could harm a nursing baby. Do not breast-feed while you are taking pravastatin.

How should I take pravastatin?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Pravastatin is usually taken once a day, with or without food. Take the medicine at the same time each day. Your doctor may occasionally change your dose to make sure you get the best results.

Multum emt

You may need to stop using pravastatin for a short time if you have:

  • uncontrolled seizures;
  • an electrolyte imbalance (such as high or low potassium levels in your blood);
  • severely low blood pressure;
  • a severe infection or illness; or
  • surgery or a medical emergency.

To be sure this medicine is helping your condition and is not causing harmful effects, your blood will need to be tested often. Visit your doctor regularly.

Pravastatin is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Multum emt

You may need to take pravastatin on a long-term basis for the treatment of high cholesterol.

Multum rt

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking pravastatin?

If you also take cholestyramine (Prevalite, Questran) or colestipol (Colestid), avoid taking them within 1 hour after or 4 hours before you take pravastatin.

Avoid eating foods that are high in fat or cholesterol. Pravastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Multum noalcohol

Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.

Grapefruit and grapefruit juice may interact with pravastatin. Discuss the use of grapefruit products with your doctor.

What are the possible side effects of pravastatin?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Stop taking pravastatin and call your doctor at once if you have any of these serious side effects:

  • unexplained muscle pain, tenderness, or weakness;
  • confusion, memory problems;
  • fever, unusual tiredness, and dark colored urine;
  • chest pain;
  • increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss);
  • swelling, weight gain, urinating less than usual or not at all; or
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • headache;
  • mild muscle pain;
  • diarrhea;
  • mild skin rash; or
  • dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect pravastatin?

Tell your doctor about all other medications you use, especially:

  • cimetidine (Tagamet);
  • spironolactone (Aldactone, Aldactazide); or
  • any other "statin" medication such as atorvastatin (Lipitor, Caduet), fluvastatin (Lescol), lovastatin (Altoprev, Mevacor), rosuvastatin (Crestor), or simvastatin (Zocor, Simcor, Vytorin).

This list is not complete and other drugs may interact with pravastatin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about pravastatin.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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