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bismuth subsalicylate

Pronunciation: BIZ muth sub sa LISS i late

Brand: Bismarex, Bismatrol, Bismatrol Maximum Strength, Kao-Tin Bismuth Subsalicylate Formula, Kaopectate, Maalox Total Stomach Relief, Peptic Relief, Pepto-Bismol, Pepto-Bismol Maximum Strength, Pink Bismuth

What is the most important information I should know about bismuth subsalicylate?

Multum nochild

This medication should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Salicylates can cause a serious and sometimes fatal condition called Reye's syndrome in children.

Multum donot

You should not use bismuth subsalicylate if you have a stomach ulcer, a recent history of stomach or intestinal bleeding, or if you are allergic to salicylates such as aspirin, Doan's Extra Strength, Salflex, Tricosal, and others.

Do not take more than 8 doses in one day (24 hours).

Bismuth subsalicylate can cause you to have a black or darkened tongue. This is a harmless side effect.

This medication can also cause unusual results with certain medical tests, thyroid scans, or stomach x-rays. Tell any doctor who treats you that you have recently taken bismuth subsalicylate.

What is bismuth subsalicylate?

Bismuth subsalicylate is an antacid and anti-diarrhea medication.

Bismuth subsalicylate is used to treat diarrhea, nausea, heartburn, indigestion, and upset stomach.

Bismuth subsalicylate may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before taking bismuth subsalicylate?

Multum nochild

This medication should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Subsalicylate can cause a serious and sometimes fatal condition called Reye's syndrome in children.

Multum donot

You should not use bismuth subsalicylate if you are allergic to it, or if you have:

  • a stomach ulcer;
  • a recent history of stomach or intestinal bleeding; or
  • if you are allergic to salicylates such as aspirin, Doan's Extra Strength, Salflex, Tricosal, and others.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

  • fever;
  • mucus in your stools;
  • diabetes;
  • arthritis; or
  • gout.
Multum nopreg

Do not take bismuth subsalicylate without medical advice if you are pregnant.

Multum nobrfeed

Bismuth subsalicylate can pass into breast milk and may harm a nursing baby. Do not use this medication without medical advice if you are breast-feeding a baby.

How should I take bismuth subsalicylate?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Multum donot

Do not take more than 8 doses in one day (24 hours).

Multum shake

Shake the liquid medicine well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

The chewable tablet must be chewed before you swallow it.

Bismuth subsalicylate can cause you to have a black or darkened tongue. This is a harmless side effect.

This medication can also cause unusual results with certain medical tests, thyroid scans, or stomach x-rays. Tell any doctor who treats you that you have recently taken bismuth subsalicylate.

Multum rt

Store at room temperature away from moisture and heat. Do not freeze.

What happens if I miss a dose?

Since bismuth subsalicylate is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. Do not take more than 8 doses in one day (24 hours).

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include increased thirst, anxiety, muscle spasm, ringing in your ears, dizziness, confusion, severe headache, problems with speech or vision, severe stomach pain, or worsening diarrhea or vomiting.

What should I avoid while taking bismuth subsalicylate?

Ask your doctor or pharmacist before taking other antacids or diarrhea medications together with bismuth subsalicylate.

What are the possible side effects of bismuth subsalicylate?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Stop taking this medicine and call your doctor at once if you have a serious side effect such as:

  • hearing loss or ringing in your ears;
  • diarrhea lasting longer than 2 days; or
  • worsened stomach symptoms.

Less serious side effects include:

  • constipation;
  • dark colored stools; or
  • black or darkened tongue.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect bismuth subsalicylate?

Ask a doctor or pharmacist if it is safe for you to use bismuth subsalicylate if you are also using any of the following drugs:

  • a blood thinner such as warfarin (Coumadin, Jantoven);
  • insulin or oral diabetes medications;
  • probenecid (Benemid);
  • an antibiotic such as doxycycline (Doryx, Oracea, Periostat, Vibramycin), minocycline (Dynacin, Minocin, Solodyn), or tetracycline (Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap);
  • medication used to prevent blood clots, such as alteplase (Activase), tenecteplase (TNKase), urokinase (Abbokinase); or
  • other salicylates such as aspirin, Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others.

This list is not complete and other drugs may interact with bismuth subsalicylate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about bismuth subsalicylate.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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