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azelastine and fluticasone nasal

Pronunciation: AY zel AS teen and floo TIK a sone

Brand: Dymista

What is the most important information I should know about azelastine and fluticasone nasal?

Multum donot

You should not use this medication if you are allergic to azelastine (Astelin, Astepro, Optivar) or fluticasone (Advair, Cutivate, Flovent, Flonase, Veramyst), or if you are also taking ritonavir (Norvir, Kaletra).

Before using azelastine and fluticasone nasal, tell your doctor if you have glaucoma or cataracts, diabetes, herpes simplex virus of your eyes, tuberculosis or any other infection, sores or ulcers inside your nose, or if you have recently had injury of or surgery on your nose.

It may take up to several days of using this medicine before your symptoms improve. Tell your doctor if your symptoms do not improve after a week of treatment.

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Fluticasone can lower blood cells that help your body fight infections. Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medication.

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Do not share this medication with other people, even if they have the same symptoms you have.

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Do not give this medicine to a child younger than 12 years old without medical advice. Steroid medication can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

Throw the medication away after you have used 120 sprays, even if there is still medicine left in the bottle.

What is azelastine and fluticasone nasal?

Azelastine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Fluticasone is a steroid. It prevents the release of substances in the body that cause inflammation.

The combination of azelastine and fluticasone is used to treat nasal symptoms such as congestion, sneezing, and runny nose caused by seasonal allergies. Fluticasone nasal is for use in adults and children who are at least 12 years old.

Fluticasone nasal may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking azelastine and fluticasone nasal?

Multum donot

You should not use this medication if you are allergic to azelastine (Astelin, Astepro, Optivar) or fluticasone (Advair, Cutivate, Flovent, Flonase, Veramyst), or if you are also taking ritonavir (Norvir, Kaletra).

To make sure you can safely use this medication, tell your doctor if you have any of these other conditions:

  • glaucoma or cataracts;
  • herpes simplex virus of your eyes;
  • tuberculosis or any other infection or illness;
  • sores or ulcers inside your nose; or
  • if you have recently had injury of or surgery on your nose.

Also tell your doctor if you have diabetes. Steroid medicines may increase the glucose (sugar) levels in your blood or urine. You may also need to adjust the dose of your diabetes medications.

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FDA pregnancy category C. It is not known whether azelastine and fluticasone nasal will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

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It is not known whether azelastine and fluticasone nasal passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Multum nochild

Do not give this medicine to a child younger than 12 years old without medical advice. Steroid medication can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

Multum donot

Do not share this medication with other people, even if they have the same symptoms you have.

How should I use azelastine and fluticasone nasal?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Before using the spray for the first time, you must prime the spray pump. Shake the medicine well and spray 6 test sprays into the air and away from your face. Prime the spray pump any time you have not used your nasal spray for longer than 2 weeks. Spray until a fine mist appears.

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Shake the medicine bottle gently just before each use.

The usual dose of azelastine and fluticasone nasal is 1 spray into each nostril twice per day. Follow your doctor's instructions.

It may take up to several days before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after a week of treatment.

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Fluticasone can lower blood cells that help your body fight infections. Tell your doctor at once if you develop signs of infection.

To be sure this medication is not causing harmful effects on your nose or sinuses, your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.

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Store in an upright position at room temperature, away from moisture and heat. Keep the dust cap on this medicine when not in use. Throw the medication away after you have used 120 sprays, even if there is still medicine left in the bottle.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

An overdose of azelastine and fluticasone is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using azelastine and fluticasone nasal?

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Avoid getting the spray in your eyes or mouth. If this does happen, rinse with water for at least 10 minutes.

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This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

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Drinking alcohol can increase certain side effects of azelastine.

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Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medication.

What are the possible side effects of azelastine and fluticasone nasal?

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

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Call your doctor at once if you have a serious side effect such as:

  • severe or ongoing nosebleeds;
  • noisy breathing, runny nose, or crusting around your nostrils;
  • redness, sores, or white patches in your mouth or throat;
  • fever, chills, weakness, nausea, vomiting, flu symptoms;
  • any wound that will not heal; or
  • blurred vision, eye pain, or seeing halos around lights.

Less serious side effects may include:

  • drowsiness;
  • minor nosebleed;
  • altered sense of taste;
  • headache; or
  • sinus pain, cough, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect azelastine and fluticasone nasal?

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Before using azelastine and fluticasone nasal, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by azelastine.

Tell your doctor about all other medicines you use, especially:

  • conivaptan (Vaprisol);
  • imatinib (Gleevec);
  • isoniazid (for treating tuberculosis);
  • nefazodone (an antidepressant);
  • an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), rifampin (Rifater, Rifadin, Rifamate), or telithromycin (Ketek);
  • antifungal medication such as fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig), posaconazole (Noxafil), or voriconazole (Vfend);
  • heart or blood pressure medication such as nicardipine (Cardene) or quinidine (Quin-G);
  • the hepatitis C medications boceprevir (Victrelis) or telaprevir (Incivek); or
  • HIV/AIDS medication such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), or saquinavir (Invirase).

This list is not complete and other drugs may interact with azelastine and fluticasone nasal. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about azelastine and fluticasone nasal.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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