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benztropine

Pronunciation: BENZ troe peen

Brand: Cogentin

Benztropine 0.5 mg-IVA

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Benztropine 0.5 mg-UPS

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Benztropine 1 mg-IVA

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Benztropine 1 mg-ROS

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Benztropine 2 mg-PAR

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Benztropine 2 mg-UPS

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What is the most important information I should know about benztropine?

Multum donot

You should not take this medication if you are allergic to benztropine, or if you are also taking a medication called pramlintide (Symlin).

Before you take benztropine, tell if you have glaucoma, kidney or liver disease, heart disease, high blood pressure, a history of heart attack or stroke, a breathing disorder, a nerve or muscle disorder, seizures, urination problems, overactive thyroid, mental illness, or a stomach or intestinal disorder.

Avoid taking a diarrhea medication or antacid within 2 hours before or after you take benztropine. Also avoid taking ketoconazole (Nizoral) within 2 hours after you take benztropine.

Multum dizzy

Benztropine may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Benztropine can decrease perspiration and you may be more prone to heat stroke.

Multum donot

Do not stop taking this medication without first talking to your doctor. Stopping suddenly may make your condition worse. You may need to use less and less before you stop the medication completely.

What is benztropine?

Benztropine reduces the effects of certain chemicals in the body that may become unbalanced as a result of disease (such as Parkinson's), drug therapy, or other causes.

Benztropine is used to treat the symptoms of Parkinson's disease, such as muscle spasms, stiffness, tremors, sweating, drooling, and poor muscle control.

Benztropine is also used to treat and prevent these symptoms when they are caused by drugs such as chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), and others.

Benztropine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking benztropine?

Multum donot

You should not take this medication if you are allergic to benztropine, or if you are also taking a medication called pramlintide (Symlin).

To make sure you can safely take benztropine, tell your doctor if you have any of these other conditions:

  • glaucoma;
  • heart disease, a heart rhythm disorder, history of heart attack;
  • high or low blood pressure;
  • asthma, emphysema, or other breathing disorder;
  • kidney or liver disease;
  • a nerve disorder;
  • a muscle disorder such as myasthenia gravis;
  • seizures;
  • enlarged prostate, urination problems;
  • overactive thyroid;
  • mental illness or dementia;
  • stomach ulcer, reflux disease, hiatal hernia; or
  • ulcerative colitis, history of bowel obstruction, or other intestinal disorder.
Multum nopreg

It is not known whether benztropine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Multum nobrfeed

It is not known whether benztropine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Multum nochild

Benztropine should not be given to a child younger than 3 years old.

How should I take benztropine?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

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Drink plenty of liquids while you are taking benztropine.

Benztropine is sometimes given up to 4 times daily, at meals and at bedtime. If you take benztropine only once per day, it may be best to take the medication at bedtime. Follow your doctor's instructions.

Multum food

Benztropine can be taken with food to lessen stomach upset.

Your mouth may feel dry while taking benztropine. To prevent or relieve dry mouth, suck on a piece of sugar-free hard candy, chew sugar-free gum, drink water, chew on ice chips, or use a saliva substitute.

Dry mouth may lead to gum disease or cavities. Brush and floss your teeth regularly and see a dentist for routine check-ups while you are taking benztropine.

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It may take up to 3 days before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve or if they get worse.

Multum donot

Do not stop taking this medication without first talking to your doctor. Stopping suddenly may make your condition worse. You may need to use less and less before you stop the medication completely.

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Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Since benztropine is sometimes taken only when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose can cause confusion, severe dizziness, hallucinations, loss of balance or coordination, vomiting, heavy sweating, hot and dry skin, numbness, urinating less than usual, dilated pupils, fast or pounding heartbeats, muscle weakness, weak or shallow breathing, buzzing in your ears, seizures, and fainting.

What should I avoid while taking benztropine?

Avoid taking a diarrhea medication (such as Kaopectate, Donnagel, or Rheaban) or an antacid (such as Amphojel, Maalox, Mylanta, Rolaids, Rulox, or Tums) within 2 hours before or after you take benztropine. These medications can make it harder for your body to absorb benztropine, which can make it less effective.

Also avoid taking ketoconazole (Nizoral) within 2 hours after you take benztropine. Benztropine can make it harder for your body to absorb ketoconazole.

Multum dizzy

Benztropine may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Multum noalcohol

Drinking alcohol can increase certain side effects of benztropine.

Multum nosun

Avoid becoming overheated or dehydrated during exercise and in hot weather. Benztropine can decrease perspiration and you may be more prone to heat stroke.

What are the possible side effects of benztropine?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Call your doctor at once if you have a serious side effect such as:

  • pounding heartbeats or fluttering in your chest;
  • feeling very weak;
  • feeling too weak to move;
  • confusion, hallucinations, unusual thoughts or behavior;
  • urinating less than usual or not at all;
  • severe constipation;
  • dry mouth that interferes with speech, swallowing, appetite, or eating;
  • feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
  • blurred vision, eye pain, or seeing halos around lights; or
  • twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs.

Less serious side effects may include:

  • depressed mood, memory problems;
  • drowsiness, feeling nervous or excited;
  • nausea, upset stomach;
  • dry mouth (mild);
  • double vision, increased sensitivity to light; or
  • numbness in your fingers;

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect benztropine?

Multum dizzy

Before using benztropine, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by benztropine.

Tell your doctor about all other medications you use, especially:

  • amantadine (Symmetrel);
  • glycopyrrolate (Robinul);
  • mepenzolate (Cantil);
  • a diuretic (water pill);
  • potassium supplements (K-Lyte, K-Dur, Klor-Con, and others);
  • an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), doxepin (Sinequan), nortriptyline (Pamelor), and others;
  • atropine (Atreza, Sal-Tropine), belladonna (Donnatal, and others), dimenhydrinate (Dramamine), meclizine (Antivert), methscopolamine (Pamine), or scopolamine (Transderm-Scop);
  • bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);
  • bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva);
  • irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine);
  • medicine to treat Alzheimer's dementia, such as donepezil (Aricept) or galantamine (Razadyne); or
  • medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), fluphenazine (Permitil, Prolixin), haloperidol (Haldol); perphenazine (Trilafon), prochlorperazine (Compazine, Compro), promethazine (Pentazine, Phenergan, Anergan, Antinaus), thioridazine (Mellaril), or trifluoperazine (Stelazine).

This list is not complete and other drugs may interact with benztropine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about benztropine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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