Skip to Content
UW Health SMPH
American Family Children's Hospital
DONATE Donate
SHARE TEXT

cilostazol

Pronunciation: sil OS tah zol

Brand: Pletal

Cilostazol 100 mg-APO

round, white, imprinted with APO, CIL 100

Image of Cilostazol 100 mg-APO
slide 1 of 10
    

Cilostazol 100 mg-MYL

round, white, imprinted with M C42

Image of Cilostazol 100 mg-MYL
slide 2 of 10
    

Cilostazol 100 mg-ROX

round, white, imprinted with 54 757

Image of Cilostazol 100 mg-ROX
slide 3 of 10
    

Cilostazol 100 mg-TEV

round, white, imprinted with 7231, 9 3

Image of Cilostazol 100 mg-TEV
slide 4 of 10
    

Cilostazol 50 mg-AND

round, white, imprinted with G, CL 50

Image of Cilostazol 50 mg-AND
slide 5 of 10
    

Cilostazol 50 mg-APO

round, white, imprinted with APO, CIL 50

Image of Cilostazol 50 mg-APO
slide 6 of 10
    

Cilostazol 50 mg-MYL

round, white, imprinted with M C41

Image of Cilostazol 50 mg-MYL
slide 7 of 10
    

Cilostazol 50 mg-ROX

round, white, imprinted with 54 521

Image of Cilostazol 50 mg-ROX
slide 8 of 10
    

Cilostazol 50 mg-SAN

round, white, imprinted with E 123

Image of Cilostazol 50 mg-SAN
slide 9 of 10
    

Cilostazol 50 mg-TEV

rectangular, white, imprinted with 7230, 9 3

Image of Cilostazol 50 mg-TEV
slide 10 of 10
    

What is the most important information I should know about cilostazol?

Multum donot

Do not take cilostazol if you have congestive heart failure. Cilostazol can make this condition worse.

It may take up to 12 weeks of using cilostazol before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 4 weeks of treatment.

Grapefruit and grapefruit juice may interact with cilostazol. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

Multum stomach

Take cilostazol on an empty stomach, at least 30 minutes before or 2 hours after food.

What is cilostazol?

Cilostazol widens arteries that supply blood to the legs. Cilostazol also improves circulation by keeping platelets in the blood from sticking together and clotting.

Cilostazol is used to treat the symptoms of intermittent claudication. This condition causes reduced blood flow to the legs, leading to pain while walking. Cilostazol improves your ability to walk longer distances without pain.

Cilostazol may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking cilostazol?

Multum donot

Do not take cilostazol if you have congestive heart failure. Cilostazol can make this condition worse.

Before using cilostazol, tell your doctor if you have:

  • heart disease; or
  • liver disease.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

Multum nopreg

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Multum nobrfeed

Cilostazol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take cilostazol?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Multum water

Take each dose with a full glass of water.

Multum stomach

Cilostazol is usually taken twice a day, at least 30 minutes before or 2 hours after breakfast or dinner. Take cilostazol at the same times each day. Follow your doctor's instructions.

It may take up to 12 weeks of using cilostazol before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 4 weeks of treatment.

Multum rt

Store cilostazol at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include a severe headache, diarrhea, feeling light-headed, fainting, and fast or uneven heartbeats.

What should I avoid while taking cilostazol?

Grapefruit and grapefruit juice may interact with cilostazol. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

What are the possible side effects of cilostazol?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum emt

Call your doctor at once if you have any of these serious side effects:

  • severe headache;
  • bloody urine, painful urination;
  • fever, chills, body aches, flu symptoms;
  • chest pain;
  • feeling short of breath, even with mild exertion; or
  • swelling of your ankles or feet.

Less serious side effects may include:

  • fast or pounding heartbeats;
  • diarrhea, vomiting;
  • weakness, dizziness;
  • leg cramps;
  • numbness or tingling;
  • joint pain; or
  • cough, runny or stuffy nose.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect cilostazol?

Before taking cilostazol, tell your doctor if you are using any of the following drugs:

  • clopidogrel (Plavix);
  • omeprazole (Prilosec, Zegerid) or esomeprazole (Nexium);
  • erythromycin (E.E.S., Ery-Tab, E-Mycin, Erythrocin) or clarithromycin (Biaxin);
  • ketoconazole (Nizoral), fluconazole (Diflucan), or itraconazole (Sporanox);
  • diltiazem (Cardizem, Tiazac); or
  • fluvoxamine (Luvox), fluoxetine (Prozac), sertraline (Zoloft), or nefazodone (Serzone).

This list is not complete and there may be other drugs that can interact with cilostazol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has more information about cilostazol.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2013 Cerner Multum, Inc. Version: 3.05. Revision date: 12/15/2010.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.