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alogliptin

Pronunciation: AL oh GLIP tin

Brand: Nesina

What is the most important information I should know about alogliptin?

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Do not use this medicine if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin). Alogliptin is not for treating type 1 diabetes.

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Alogliptin can cause pancreatitis. Stop using this medicine and call your doctor at once if you have severe pain in your upper stomach spreading to your back, nausea and vomiting, and loss of appetite.

What is alogliptin?

Alogliptin is an oral diabetes medicine that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating.

Alogliptin is for people with type 2 diabetes. Alogliptin is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes.

Alogliptin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking alogliptin?

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Do not use this medicine if you are allergic to alogliptin, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

To make sure alogliptin is safe for you, tell your doctor if you have:

  • liver disease;
  • kidney disease (or if you are on dialysis);
  • a history of pancreatitis;
  • gallstones; or
  • a history of alcoholism.

FDA pregnancy category B. Alogliptin is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

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It is not known whether alogliptin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

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Do not give this medication to anyone under 18 years old without medical advice.

How should I take alogliptin?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You may take this medicine with or without food. Follow your doctor's instructions.

Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office.

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Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, pale skin, irritability, dizziness, feeling shaky, or trouble concentrating.

Keep a source of sugar with you in case you have low blood sugar. Sugar sources include fruit juice, hard candy, crackers, raisins, and non-diet soda. Be sure your family and close friends know how to help you in an emergency. If you have severe hypoglycemia and cannot eat or drink, use a glucagon injection. Your doctor can prescribe a glucagon emergency injection kit and tell you how to use it.

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Check your blood sugar carefully during times of stress, travel, illness, surgery or medical emergency, vigorous exercise, or if you drink alcohol or skip meals. These things can affect your glucose levels and your dose needs may also change. Do not change your medication dose or schedule without your doctor's advice.

Alogliptin is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

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Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

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Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).

What should I avoid while taking alogliptin?

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Avoid drinking alcohol.

What are the possible side effects of alogliptin?

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

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Stop using alogliptin and call your doctor at once if you have:

  • severe pain in your upper stomach spreading to your back;
  • nausea and vomiting, loss of appetite, fast heart rate;
  • itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include:

  • headache; or
  • cold symptoms such as stuffy nose, sinus pain, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect alogliptin?

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Using certain medicines can make it harder for you to tell when you have low blood sugar. Tell your doctor if you use albuterol, clonidine, reserpine, or a beta-blocker (atenolol, metoprolol, propranolol, and others).

Other drugs may interact with alogliptin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about alogliptin.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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