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aliskiren

Pronunciation: a LIS ke rin

Brand: Tekturna

Tekturna 150 mg

round, pink, imprinted with NVR, IL

Image of Tekturna 150 mg
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Tekturna 300 mg

oval, red, imprinted with NVR, IU

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What is the most important information I should know about aliskiren?

Multum nopreg

Do not use this medication if you are pregnant. Aliskiren can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Stop using this medication and tell your doctor right away if you become pregnant.

Before you take aliskiren, tell your doctor if you have kidney disease, heart disease, if you are on a low-salt diet, or if you have ever had an allergic reaction to a heart or blood pressure medication.

If you take aliskiren with meals, avoid high-fat foods. They can make it harder for your body to absorb aliskiren.

Conditions that may cause very low blood pressure include: vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you should drink while taking aliskiren. Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

What is aliskiren?

Aliskiren is an anti-hypertensive (blood pressure lowering) medication. It works by decreasing substances in the body that narrow blood vessels and raise blood pressure.

Aliskiren is used to treat high blood pressure (hypertension).

Aliskiren may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before taking aliskiren?

Multum donot

You should not take aliskiren if you are allergic to it.

If you have diabetes or kidney disease, you may not be able to take aliskiren if you are also taking any of the following heart or blood pressure medications:

  • azilsartan (Edarbi, Edarbyclor), candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro, Avalide), losartan (Cozaar, Hyzaar), olmesartan (Benicar), valsartan (Diovan), telmisartan (Micardis); or
  • benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik, Tarka).

To make sure you can safely take aliskiren, tell your doctor if you have any of these other conditions:

  • kidney disease (or if you are on dialysis);
  • heart disease;
  • if you are on a low-salt diet; or
  • if you have ever had an allergic reaction to an ACE (angiotensin converting enzyme) inhibitor medication such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others.
Multum nopreg

FDA pregnancy category D. Do not use this medication if you are pregnant. Aliskiren can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Stop using this medication and tell your doctor right away if you become pregnant.

Multum nobrfeed

It is not known whether aliskiren passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take aliskiren?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Multum water

Take aliskiren with a full glass of water.

You may take aliskiren with or without food, but take it the same way every time.

If you take aliskiren with meals, avoid high-fat foods. They can make it harder for your body to absorb aliskiren.

Conditions that may cause very low blood pressure include: vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you should drink while taking aliskiren. Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Multum rt

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include feeling light-headed or fainting.

What should I avoid while taking aliskiren?

Multum noalcohol

Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of aliskiren.

Multum donot

Do not use salt substitutes or potassium supplements while taking aliskiren, unless your doctor has told you to.

What are the possible side effects of aliskiren?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficult breathing; swelling of your face, lips, tongue, or throat.

If you have an allergic reaction to aliskiren you should not take it again.

Multum donot

Call your doctor at once if you have a serious side effect such as:

  • feeling light-headed, fainting;
  • nausea with slow uneven heart rate and a weak pulse;
  • swelling around your eyes; or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects may include:

  • stomach pain or upset, diarrhea, heartburn;
  • itching or skin rash;
  • headache, dizziness, tired feeling;
  • back pain, joint pain or swelling; or
  • stuffy nose, sore throat, cough.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect aliskiren?

Tell your doctor about all other medicines you use, especially:

  • atorvastatin (Lipitor);
  • cyclosporine (Gengraf, Neoral, Sandimmune);
  • furosemide (Lasix);
  • antifungal medication such as fluconazole (Diflucan), itraconazole (Sporanox), or ketoconazole (Nizoral);
  • non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others;
  • a potassium supplement such as K-Dur, Klor-Con;
  • salt substitutes that contain potassium; or
  • a diuretic (water pill).

This list is not complete and other drugs may interact with aliskiren. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about aliskiren.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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