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acetaminophen and pentazocine

Pronunciation: a SEET a MIN oh fen and pen TAZ oh seen

Brand: Talacen

Acetaminophen-Pentazocine 650 mg-25 mg-WAT

oblong, turquoise, imprinted with 396 25 650, WATSON

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Talacen

oblong, blue, imprinted with T 37, Winthrop

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What is the most important information I should know about acetaminophen and pentazocine?

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

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Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).

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In rare cases, acetaminophen may cause a severe skin reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

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This medicine may be habit forming. Never share acetaminophen and pentazocine with another person, especially someone with a history of drug abuse or addiction.

What is acetaminophen and pentazocine?

Acetaminophen is a pain reliever and a fever reducer.

Pentazocine is an opioid pain medication. An opioid is sometimes called a narcotic.

Acetaminophen and pentazocine is a combination medicine used to relieve moderate to severe pain.

Acetaminophen and pentazocine may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before taking acetaminophen and pentazocine?

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You should not use this medicine if you are allergic to acetaminophen (Tylenol) or pentazocine (Talwin).

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

To make sure this medicine is safe for you, tell your doctor if you have:

  • liver disease, cirrhosis, or if you drink more than 3 alcoholic beverages per day;
  • a history of alcoholism or drug addiction;
  • diarrhea, inflammatory bowel disease;
  • bowel obstruction, severe constipation;
  • a colostomy or ileostomy;
  • kidney disease;
  • heart disease, or if you have recently had a heart attack;
  • low blood pressure, or if you are dehydrated;
  • a history of head injury, brain tumor, or stroke; or
  • asthma, COPD, sleep apnea, or other breathing disorders.
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Pentazocine may be habit forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

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FDA pregnancy category C. It is not known whether this medicine is harmful to an unborn baby, but it could cause breathing problems or addiction/withdrawal symptoms in a newborn. Tell your doctor if you are pregnant or plan to become pregnant while using acetaminophen and pentazocine.

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Acetaminophen and pentazocine can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Older adults may be more sensitive to the effects of this medicine.

How should I take acetaminophen and pentazocine?

Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed. An overdose can damage your liver or cause death. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

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Take this medicine with food or milk if it upsets your stomach.

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Drink 6 to 8 full glasses of water daily to help prevent constipation while you are taking acetaminophen and pentazocine. Do not use a stool softener (laxative) without first asking your doctor.

This medicine can cause unusual results with certain urine tests. Tell any doctor who treats you that you are using acetaminophen and pentazocine.

If you need surgery, tell the surgeon ahead of time that you are using this medicine. You may need to stop using the medicine for a short time.

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Do not stop using this medicine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using acetaminophen and pentazocine.

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Store at room temperature away from moisture and heat.

Keep track of the amount of medicine used from each new bottle. Pentazocine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I miss a dose?

Since acetaminophen and pentazocine is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

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Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen and pentazocine can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include extreme drowsiness, anxiety, nightmares, pinpoint pupils, fainting, weak pulse, blue lips, shallow breathing, or no breathing.

What should I avoid while taking acetaminophen and pentazocine?

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This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how acetaminophen and pentazocine will affect you.

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Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

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Avoid drinking alcohol while taking acetaminophen and pentazocine. Alcohol may increase your risk of liver damage while taking acetaminophen.

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Smoking tobacco can make acetaminophen and pentazocine less effective.

What are the possible side effects of acetaminophen and pentazocine?

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

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Call your doctor at once if you have:

  • weak or shallow breathing, slow heartbeat;
  • a light-headed feeling, like you might pass out;
  • confusion, hallucinations, unusual thoughts or behavior;
  • seizure (convulsions);
  • easy bruising or bleeding; or
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • drowsiness;
  • upset stomach, constipation, diarrhea;
  • dry mouth; or
  • blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect acetaminophen and pentazocine?

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Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking acetaminophen and pentazocine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Other drugs may interact with acetaminophen and pentazocine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

Your pharmacist has information about acetaminophen and pentazocine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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