Rebound congestion is a constant nasal stuffiness (congestion) that
develops from the overuse of nasal sprays (or drops or gels) that contain a decongestant medicine. This type of
congestion occurs even when a person is not experiencing allergies or other
Some examples of nasal spray decongestants are oxymetazoline (such as Afrin or Zicam Extreme Congestion Relief) and phenylephrine (such as Neo-Synephrine).
Rebound congestion can develop from using a nasal decongestant more times in one day or more days than the label says. As the medicine wears off, sinus membranes
swell, causing congestion, and a person may respond by using a higher dose of
decongestant. If the cycle continues, a person builds up a tolerance by using
larger and larger doses until congestion occurs whenever the person does not
take the medication.
Rebound congestion can lead to addiction to decongestant nasal
Patrice Burgess, MD - Family Medicine & Donald R. Mintz, MD - Otolaryngology