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Timothy J. Kamp, MD, PhD, FACC close
Timothy J. Kamp, MD, PhD, FACC

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Timothy J. Kamp, MD, PhD, FACC Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Kamp's clinical activities include general cardiology with an emphasis on noninvasive cardiac electrophysiology and heart failure. He directs an active research program which bridges from the basic functional and electrical properties of heart cells to clinical applications arising from these basic studies, including the use of stem cells to repair damaged heart muscle. Dr. Kamp participates widely in peer review activities, including the editorial board for the journals Circulation Research and Stem Cells, as well as serving on peer review panels for American Heart Association and National Institutes of Health.


Cardiovascular Medicine

UW Health Clinics

University Hospital
(608) 263-1530 | (800) 323-8942 | Map

Hospital Affiliation(s)

University of Wisconsin Hospital and Clinics (primary)
Meriter Hospital, Veterans Hospital - Wm. S. Middleton Memorial (secondary)

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Cardiovascular Disease
Fellowship Johns Hopkins Hospital, Baltimore, MD
Residency Johns Hopkins Hospital, Baltimore, MD
Internship Johns Hopkins Hospital, Baltimore, MD
Medical School University of Chicago Medical School, Chicago, IL, 1989

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Programs & Conditions


Dr. Kamp's research focuses in three general and related areas: (1) cardiac ion channel proteins and their role in the electrical activity of the heart, including arrhythmias, (2) basic cellular abnormalities responsible for heart failure, and (3) stem cells for the generation of new heart cells and for repair of damaged heart muscle.

PubMed Articles
Wendel JS Ye L Tao R Zhang J Zhang J Kamp TJ Tranquillo RT . Functional Effects of a Tissue-Engineered Cardiac Patch From Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Rat Infarct Model. Stem Cells Transl Med. 2015 Nov;4(11):1324-32
[PubMed ID: 26371342]
Hwang HS Kryshtal DO Feaster TK Sánchez-Freire V Zhang J Kamp TJ Hong CC Wu JC Knollmann BC . Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories. J Mol Cell Cardiol. 2015 Aug;85:79-88
[PubMed ID: 25982839]
Chang YH Ye L Cai W Lee Y Guner H Lee Y Kamp TJ Zhang J Ge Y . Quantitative proteomics reveals differential regulation of protein expression in recipient myocardium after trilineage cardiovascular cell transplantation. Proteomics. 2015 Aug;15(15):2560-7
[PubMed ID: 26033914]
Lian X Bao X Zilberter M Westman M Fisahn A Hsiao C Hazeltine LB Dunn KK Kamp TJ Palecek SP . Chemically defined, albumin-free human cardiomyocyte generation. Nat Methods. 2015 Jul;12(7):595-6
[PubMed ID: 26125590]
Markandeya YS Kamp TJ . Rational strategy to stop arrhythmias: Early afterdepolarizations and L-type Ca2+ current. J Gen Physiol. 2015 Jun;145(6):475-9
[PubMed ID: 26009542]
Kamp TJ January CT . Harry A. Fozzard, MD: 1931–2014. Circ Res. 2015 Feb 13;116(4):552-3
[PubMed ID: 25821880]
Raval KK Tao R White BE De Lange WJ Koonce CH Yu J Kishnani PS Thomson JA Mosher DF Ralphe JC Kamp TJ . Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes. J Biol Chem. 2015 Jan 30;290(5):3121-36
[PubMed ID: 25488666]
Bhattacharya D Mehle A Kamp TJ Balijepalli RC . Intramolecular ex vivo Fluorescence Resonance Energy Transfer (FRET) of Dihydropyridine Receptor (DHPR) β1a Subunit Reveals Conformational Change Induced by RYR1 in Mouse Skeletal Myotubes. PLoS One. 2015;10(6):e0131399
[PubMed ID: 26114725]
Wrighton PJ Klim JR Hernandez BA Koonce CH Kamp TJ Kiessling LL . Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18126-31
[PubMed ID: 25422477]
Ye L Chang YH Xiong Q Zhang P Zhang L Somasundaram P Lepley M Swingen C Su L Wendel JS Guo J Jang A Rosenbush D Greder L Dutton JR Zhang J Kamp TJ Kaufman DS Ge Y Zhang J . Cardiac repair in a porcine model of acute myocardial infarction with human induced pluripotent stem cell-derived cardiovascular cells. Cell Stem Cell. 2014 Dec 4;15(6):750-61
[PubMed ID: 25479750]
Bedada FB Chan SS Metzger SK Zhang L Zhang J Garry DJ Kamp TJ Kyba M Metzger JM . Acquisition of a quantitative, stoichiometrically conserved ratiometric marker of maturation status in stem cell-derived cardiac myocytes. Stem Cell Reports. 2014 Oct 14;3(4):594-605
[PubMed ID: 25358788]
Fox IJ Daley GQ Goldman SA Huard J Kamp TJ Trucco M . Stem cell therapy. Use of differentiated pluripotent stem cells as replacement therapy for treating disease. Science. 2014 Aug 22;345(6199):1247391
[PubMed ID: 25146295]
Spencer CI Baba S Nakamura K Hua EA Sears MA Fu CC Zhang J Balijepalli S Tomoda K Hayashi Y Lizarraga P Wojciak J Scheinman MM Aalto-Setälä K Makielski JC January CT Healy KE Kamp TJ Yamanaka S Conklin BR . Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia. Stem Cell Reports. 2014 Aug 12;3(2):269-81
[PubMed ID: 25254341]
Raval KK Kamp TJ . Cardiomyopathy, mitochondria and Barth syndrome: iPSCs reveal a connection. Nat Med. 2014 Jun;20(6):585-6
[PubMed ID: 24901565]
Salick MR Napiwocki BN Sha J Knight GT Chindhy SA Kamp TJ Ashton RS Crone WC . Micropattern width dependent sarcomere development in human ESC-derived cardiomyocytes. Biomaterials. 2014 May;35(15):4454-64
[PubMed ID: 24582552]
Lalit PA Hei DJ Raval AN Kamp TJ . Induced pluripotent stem cells for post-myocardial infarction repair: remarkable opportunities and challenges. Circ Res. 2014 Apr 11;114(8):1328-45
[PubMed ID: 24723658]
Lian X Zhang J Zhu K Kamp TJ Palecek SP . Insulin inhibits cardiac mesoderm, not mesendoderm, formation during cardiac differentiation of human pluripotent stem cells and modulation of canonical Wnt signaling can rescue this inhibition. Stem Cells. 2013 Mar;31(3):447-57
[PubMed ID: 23193013]
Lian X Zhang J Azarin SM Zhu K Hazeltine LB Bao X Hsiao C Kamp TJ Palecek SP . Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions. Nat Protoc. 2013 Jan;8(1):162-75
[PubMed ID: 23257984]
Zhang J Klos M Wilson GF Herman AM Lian X Raval KK Barron MR Hou L Soerens AG Yu J Palecek SP Lyons GE Thomson JA Herron TJ Jalife J Kamp TJ . Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method. Circ Res. 2012 Oct 12;111(9):1125-36
[PubMed ID: 22912385]
Lian X Hsiao C Wilson G Zhu K Hazeltine LB Azarin SM Raval KK Zhang J Kamp TJ Palecek SP . Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):E1848-57
[PubMed ID: 22645348]