American Family Children's Hospital
Takushi Kohmoto, MD, PhD close

Takushi Kohmoto, MD, PhD Print Friendly Page

Interim Chair, Division of Cardiothoracic Surgery
Faculty, University of Wisconsin School of Medicine and Public Health

Takushi Kohmoto, MD, specializes in coronary artery bypass surgery, beating heart surgery, aortic and mitral valve surgery, surgery for end-stage heart disease, heart transplantation, mechanical assist devices, minimally invasive cardiac surgery, cardiac arrhythmia surgery, robotic cardiac surgery, pericardiectomy and cardiac reoperation.


Cardiothoracic Surgery

Transplant Surgery

UW Health Clinics

University Hospital
(608) 263-1530 | (800) 323-8942 | Map
1 S. Park Clinic
(608) 287-2100 | (888) 703-2778 | Map
UW Health at The American Center
(608) 263-1530 | (844) 607-4800 | Map
University Hospital
(608) 262-8915 | (800) 323-8942 | Map
University Hospital
(608) 263-1530 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital (primary)
UnityPoint Health - Meriter, Veterans Hospital - Wm. S. Middleton Memorial (secondary)

UW School of Medicine and Public Health

Department of Surgery, Cardiothoracic Surgery

Professional Certifications and Education


Cardiovascular Surgery, Shin-Tokyo Hospital, Matsudo, Chiba, Japan

Assist Device, Minimally Invasive and Robotic, New York Presbyterian Hospital-Columbia University Medical Center, New York, NY


Residency Okayama University Hospital, Japan
New-Tokyo Hospital, Japan
Internship Okayama University Hospital, Japan
Medical School Okayama University School of Medicine, Japan, 1989


Madison Magazine Top Docs 2016

Best Doctors® in America 2015

Madison Magazine Top Docs 2014

Best Doctors® in America 2014

Best Doctors® in America 2013

Madison Magazine Top Docs 2012

Languages Spoken

English, Japanese
Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Dr. Kohmoto’s research interests include mechanical assist devices, heart transplantation, lung transplantation, ischemic preconditioning, laser surgery, angiogenesis, cell transplantation and cardiac regeneration.

PubMed Articles
Okada A Kohmoto T Naruto T Yokota I Kotani Y Shimada A Miyamoto Y Takahashi R Goji A Masuda K Kagami S Imoto I . The first Japanese patient with mandibular hypoplasia, deafness, progeroid features and lipodystrophy diagnosed via POLD1 mutation detection. Hum Genome Var. 2017;4:17031
[PubMed ID: 28791128]
Gregorich ZR Cai W Lin Z Chen AJ Peng Y Kohmoto T Ge Y . Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry. J Mol Cell Cardiol. 2017 Jun;107:13-21
[PubMed ID: 28427997]
Cai W Tucholski T Chen B Alpert AJ McIlwain S Kohmoto T Jin S Ge Y . Top-Down Proteomics of Large Proteins up to 223 kDa Enabled by Serial Size Exclusion Chromatography Strategy. Anal Chem. 2017 May 16;89(10):5467-5475
[PubMed ID: 28406609]
Jin Y Wei L Cai W Lin Z Wu Z Peng Y Kohmoto T Moss RL Ge Y . Complete Characterization of Cardiac Myosin Heavy Chain (223 kDa) Enabled by Size-Exclusion Chromatography and Middle-Down Mass Spectrometry. Anal Chem. 2017 May 2;89(9):4922-4930
[PubMed ID: 28366003]
Tang PC Badami A Akhter SA Osaki S Lozonschi L Kohmoto T De Oliveira N . Efficacy of Aortic Valve Resuspension in Establishing Valve Competence in Acute Type A Dissections. Ann Thorac Surg. 2017 May;103(5):1460-1466
[PubMed ID: 27863732]
Lushaj EB Dhingra R Chindhy S Akhter S Kohmoto T Ulschmid S Osaki S Badami A Lozonschi L . To use or not to use? Amiodarone before heart transplantation. Surgery. 2017 May;161(5):1273-1278
[PubMed ID: 27876282]
Kohmoto T Okamoto N Naruto T Murata C Ouchi Y Fujita N Inagaki H Satomura S Okamoto N Saito M Masuda K Kurahashi H Imoto I . A case with concurrent duplication, triplication, and uniparental isodisomy at 1q42.12-qter supporting microhomology-mediated break-induced replication model for replicative rearrangements. Mol Cytogenet. 2017;10:15
[PubMed ID: 28465723]
Kohmoto T Naruto T Watanabe M Fujita Y Ujiro S Okamoto N Horikawa H Masuda K Imoto I . A 590 kb deletion caused by non-allelic homologous recombination between two LINE-1 elements in a patient with mesomelia-synostosis syndrome. Am J Med Genet A. 2017 Apr;173(4):1082-1086
[PubMed ID: 28328141]
Okamoto N Watanabe M Naruto T Matsuda K Kohmoto T Saito M Masuda K Imoto I . Genome-first approach diagnosed Cabezas syndrome via novel CUL4B mutation detection. Hum Genome Var. 2017;4:16045
[PubMed ID: 28144446]
Kajiura K Masuda K Naruto T Kohmoto T Watabnabe M Tsuboi M Takizawa H Kondo K Tangoku A Imoto I . Frequent silencing of the candidate tumor suppressor TRIM58 by promoter methylation in early-stage lung adenocarcinoma. Oncotarget. 2017 Jan 10;8(2):2890-2905
[PubMed ID: 27926516]
Watanabe M Nakagawa R Kohmoto T Naruto T Suga KI Goji A Horikawa H Masuda K Kagami S Imoto I . Exome-first approach identified a novel gloss deletion associated with Lowe syndrome. Hum Genome Var. 2016;3:16037
[PubMed ID: 27867521]
Watanabe M Nakagawa R Naruto T Kohmoto T Suga K Goji A Kagami S Masuda K Imoto I . A novel missense mutation of COL5A2 in a patient with Ehlers-Danlos syndrome. Hum Genome Var. 2016;3:16030
[PubMed ID: 27656288]
Watanabe M Hayabuchi Y Ono A Naruto T Horikawa H Kohmoto T Masuda K Nakagawa R Ito H Kagami S Imoto I . Detection of 1p36 deletion by clinical exome-first diagnostic approach. Hum Genome Var. 2016;3:16006
[PubMed ID: 28428889]
Kohmoto T Shono M Naruto T Watanabe M Suga K Nakagawa R Kagami S Masuda K Imoto I . A novel frameshift mutation of CHD7 in a Japanese patient with CHARGE syndrome. Hum Genome Var. 2016;3:16004
[PubMed ID: 27081570]
Kohmoto T Tsuji A Morita K Naruto T Masuda K Kashimada K Enomoto K Morio T Harada H Imoto I . A novel COL11A1 missense mutation in siblings with non-ocular Stickler syndrome. Hum Genome Var. 2016;3:16003
[PubMed ID: 27081569]
Hamada J Shoda K Masuda K Fujita Y Naruto T Kohmoto T Miyakami Y Watanabe M Kudo Y Fujiwara H Ichikawa D Otsuji E Imoto I . Tumor-promoting function and prognostic significance of the RNA-binding protein T-cell intracellular antigen-1 in esophageal squamous cell carcinoma. Oncotarget. 2016 Mar 29;7(13):17111-28
[PubMed ID: 26958940]
Morine M Kohmoto T Masuda K Inagaki H Watanabe M Naruto T Kurahashi H Maeda K Imoto I . A unique TBX5 microdeletion with microinsertion detected in patient with Holt-Oram syndrome. Am J Med Genet A. 2015 Dec;167A(12):3192-6
[PubMed ID: 26780237]
Kohmoto T Naruto T Kobayashi H Watanabe M Okamoto N Masuda K Imoto I Okamoto N . A novel COL11A1 mutation affecting splicing in a patient with Stickler syndrome. Hum Genome Var. 2015;2:15043
[PubMed ID: 27081549]
Akhter SA Badami A Murray M Kohmoto T Lozonschi L Osaki S Lushaj EB . Hospital Readmissions After Continuous-Flow Left Ventricular Assist Device Implantation: Incidence, Causes, and Cost Analysis. Ann Thorac Surg. 2015 Sep;100(3):884-9
[PubMed ID: 26095106]
Chen YC Ayaz-Guner S Peng Y Lane NM Locher M Kohmoto T Larsson L Moss RL Ge Y . Effective top-down LC/MS+ method for assessing actin isoforms as a potential cardiac disease marker. Anal Chem. 2015 Aug 18;87(16):8399-8406
[PubMed ID: 26189812]