Shahab A. Akhter, MD Print Friendly PageFaculty, University of Wisconsin School of Medicine and Public Health
Dr. Akhter is certified by the American Board of Surgery and the American Board of Thoracic Surgery. He specializes in complex and high-risk cardiac surgery in adults. His particular areas of expertise include mitral and tricuspid valve repair, ventricular assist devices and heart transplantation, minimally-invasive surgery for the treatment of atrial fibrillation, and re-operative cardiac surgery. Dr. Akhter also performs coronary artery bypass grafting, minimally invasive valve surgery, and transcatheter valve replacement.
UW Health Clinics
|Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.|
UW School of Medicine and Public Health
|Department of Surgery|
Professional Certifications and Education
Thoracic and Cardiac Surgery
Cardiothoracic Surgery, University of Michigan Medical Center, Ann Arbor, MI
Duke University Medical Center, Durham, NC
University of Michigan Medical Center, Ann Arbor, MI
Duke University Medical Center, Durham, NC
University of Chicago, Pritzker School of Medicine, Chicago, IL, 1993
Our doctors provide a wide range of services. The following list represents some, but not all, of the procedures offered by this physician.
- Aortic Valve Sparing Surgery
- Balloon Angioplasty
- Cardiac Resynchronization Device
- Carotid Artery Stenting
- Carotid Artery Surgery
- Coronary Artery Bypass Graft (CABG)
- Electrophysiology Study
- Fluoresence Endoscopic Surveillance
- Heart Pacemaker
- Limb Salvage Surgery
- Maze Procedure
- Mitral Valve Repair
- Photodynamic Therapy
Dr. Akhter's clinical research focuses on optimizing outcomes in mechanical circulatory support for advanced heart failure and developing novel approaches for minimally invasive arrhythmia surgery. His laboratory research program investigates molecular mechanisms involved in the development of heart failure, with the goal of discovering novel therapeutic strategies to prevent this disease process.
Naik A Akhter SA Fedson S Jeevanandam V Rich JD Koyner JL .
Acute Kidney Injury and Mortality following Ventricular Assist Device Implantation. Am J Nephrol. 2014 Feb 15;39(3):195-203
[PubMed ID: 24556808]
Russo MJ Merlo A Johnson EM Akhter S McCarney S Steiman J Anderson A Jeevanandam V .
Transapical approach for mitral valve repair during insertion of a left ventricular assist device. ScientificWorldJournal. 2013;2013:925310
[PubMed ID: 23878531]
Akhter SA .
Invited commentary. Ann Thorac Surg. 2013 Apr;95(4):1281
[PubMed ID: 23522195]
Akhter SA .
Invited commentary. Ann Thorac Surg. 2013 Jan;95(1):61-2
[PubMed ID: 23272829]
Piao L Fang YH Parikh KS Ryan JJ D'Souza KM Theccanat T Toth PT Pogoriler J Paul J Blaxall BC Akhter SA Archer SL .
GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension. Circulation. 2012 Dec 11;126(24):2859-69
[PubMed ID: 23124027]
Iribarne A Burgener JD Hong K Raman J Akhter S Easterwood R Jeevanandam V Russo MJ .
Quantifying the incremental cost of complications associated with mitral valve surgery in the United States. J Thorac Cardiovasc Surg. 2012 Apr;143(4):864-72
[PubMed ID: 22424521]
Malhotra R Valuckaite V Staron ML Theccanat T D'Souza KM Alverdy JC Akhter SA .
High-molecular-weight polyethylene glycol protects cardiac myocytes from hypoxia- and reoxygenation-induced cell death and preserves ventricular function. Am J Physiol Heart Circ Physiol. 2011 May;300(5):H1733-42
[PubMed ID: 21335476]
Akhter SA .
The heart and pericardium. Thorac Surg Clin. 2011 May;21(2):205-17, viii
[PubMed ID: 21477771]
D'Souza KM Malhotra R Philip JL Staron ML Theccanat T Jeevanandam V Akhter SA .
G protein-coupled receptor kinase-2 is a novel regulator of collagen synthesis in adult human cardiac fibroblasts. J Biol Chem. 2011 Apr 29;286(17):15507-16
[PubMed ID: 21357420]
Koyner JL Vaidya VS Bennett MR Ma Q Worcester E Akhter SA Raman J Jeevanandam V O'Connor MF Devarajan P Bonventre JV Murray PT .
Urinary biomarkers in the clinical prognosis and early detection of acute kidney injury. Clin J Am Soc Nephrol. 2010 Dec;5(12):2154-65
[PubMed ID: 20798258]
Lin E Boire A Hemmige V Husain AN Sorrentino M Nathan S Akhter SA Dickstein J Archer SL .
Cardiac tamponade mimicking tuberculous pericarditis as the initial presentation of chronic lymphocytic leukemia in a 58-year-old woman: a case report. J Med Case Rep. 2010 Aug 4;4:246
[PubMed ID: 20684780]
Akhter SA D'Souza KM Malhotra R Staron ML Valeroso TB Fedson SE Anderson AS Raman J Jeevanandam V .
Reversal of impaired myocardial beta-adrenergic receptor signaling by continuous-flow left ventricular assist device support. J Heart Lung Transplant. 2010 Jun;29(6):603-9
[PubMed ID: 20202864]
Malhotra R D'Souza KM Staron ML Birukov KG Bodi I Akhter SA .
G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C. J Biol Chem. 2010 Apr 30;285(18):13748-60
[PubMed ID: 20194499]
Akhter SA Raman J Jeevanandam V .
Technique for left ventricular apical cannulation for short-term mechanical circulatory support. Ann Thorac Surg. 2010 Mar;89(3):994-5
[PubMed ID: 20172185]
Bulcao CF D'Souza KM Malhotra R Staron M Duffy JY Pandalai PK Jeevanandam V Akhter SA .
Activation of JAK-STAT and nitric oxide signaling as a mechanism for donor heart dysfunction. J Heart Lung Transplant. 2010 Mar;29(3):346-51
[PubMed ID: 20022263]
Rajan S Jagatheesan G Karam CN Alves ML Bodi I Schwartz A Bulcao CF D'Souza KM Akhter SA Boivin GP Dube DK Petrashevskaya N Herr AB Hullin R Liggett SB Wolska BM Solaro RJ Wieczorek DF .
Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform. Circulation. 2010 Jan 26;121(3):410-8
[PubMed ID: 20065163]
Bulcao CF Pandalai PK D'Souza KM Merrill WH Akhter SA .
Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2. Ann Thorac Surg. 2008 Oct;86(4):1189-94
[PubMed ID: 18805158]
Pandalai PK McLean KM Bulcao CF Duffy JY D'Souza KM Merrill WH Pearl JM Akhter SA .
Acute beta-blockade prevents myocardial beta-adrenergic receptor desensitization and preserves early ventricular function after brain death. J Thorac Cardiovasc Surg. 2008 Apr;135(4):792-8
[PubMed ID: 18374758]
D'Souza KM Petrashevskaya NN Merrill WH Akhter SA .
Inhibition of protein kinase C alpha improves myocardial beta-adrenergic receptor signaling and ventricular function in a model of myocardial preservation. J Thorac Cardiovasc Surg. 2008 Jan;135(1):172-9, 179.e1
[PubMed ID: 18179937]
McLean KM Pandalai PK Pearl JM Bulcao CF Lyons JM Wagner CJ Akhter SA Duffy JY .
Beta-adrenergic receptor antagonism preserves myocardial function after brain death in a porcine model. J Heart Lung Transplant. 2007 May;26(5):522-8
[PubMed ID: 17449424]