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American Family Children's Hospital
Shahab A. Akhter, MD close
Shahab A. Akhter, MD

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Shahab A. Akhter, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Akhter is certified by the American Board of Surgery and the American Board of Thoracic Surgery. He specializes in complex and high-risk cardiac surgery in adults. His particular areas of expertise include mitral and tricuspid valve repair, ventricular assist devices and heart transplantation, minimally-invasive surgery for the treatment of atrial fibrillation, and re-operative cardiac surgery. Dr. Akhter also performs coronary artery bypass grafting, minimally invasive valve surgery, and transcatheter valve replacement.


Cardiothoracic Surgery

Transplant Surgery

UW Health Clinics

UW Hospital and Clinics
(608) 263-1530 | (800) 323-8942 | Map
UW Hospital and Clinics
(608) 262-8915 | (800) 323-8942 | Map
UW Hospital and Clinics
(608) 263-1530 | (800) 323-8942 | Map

Hospital Affiliation(s)

University of Wisconsin Hospital and Clinics (primary)
Meriter Hospital, Veterans Hospital - Wm. S. Middleton Memorial (secondary)

UW School of Medicine and Public Health

Department of Surgery

Professional Certifications and Education

Board Certification Surgery
Thoracic and Cardiac Surgery

Cardiothoracic Surgery, University of Michigan Medical Center, Ann Arbor, MI

Residency Duke University Medical Center, Durham, NC
University of Michigan Medical Center, Ann Arbor, MI
Internship Duke University Medical Center, Durham, NC
Medical School University of Chicago, Pritzker School of Medicine, Chicago, IL, 1993

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.


Our doctors provide a wide range of services. The following list represents some, but not all, of the procedures offered by this physician.

Programs & Conditions


Dr. Akhter's clinical research focuses on optimizing outcomes in mechanical circulatory support for advanced heart failure and developing novel approaches for minimally invasive arrhythmia surgery. His laboratory research program investigates molecular mechanisms involved in the development of heart failure, with the goal of discovering novel therapeutic strategies to prevent this disease process.

PubMed Articles
Lushaj EB Badami A Osaki S Murray M Leverson G Lozonschi L Akhter S Kohmoto T . Impact of age on outcomes following continuous-flow left ventricular assist device implantation. Interact Cardiovasc Thorac Surg. 2015 Mar 13;
[PubMed ID: 25770085]
Xu X Philip JL Razzaque MA Lloyd JW Muller CM Akhter SA . High-molecular-weight polyethylene glycol inhibits myocardial ischemia-reperfusion injury in vivo. J Thorac Cardiovasc Surg. 2015 Feb;149(2):588-93
[PubMed ID: 25455467]
Dean D Kallel F Ewald GA Tatooles A Sheridan BC Brewer RJ Caldeira C Farrar DJ Akhter SA . Reduction in driveline infection rates: Results from the HeartMate II Multicenter Driveline Silicone Skin Interface (SSI) Registry. J Heart Lung Transplant. 2014 Dec 5;
[PubMed ID: 25735901]
Singh A Russo MJ Valeroso TB Anderson AS Rich JD Jeevanandam V Akhter SA . Modified HeartMate II driveline externalization technique significantly decreases incidence of infection and improves long-term survival. ASAIO J. 2014 Nov-Dec;60(6):613-6
[PubMed ID: 25072552]
Gemel J Levy AE Simon AR Bennett KB Ai X Akhter S Beyer EC . Connexin40 abnormalities and atrial fibrillation in the human heart. J Mol Cell Cardiol. 2014 Nov;76:159-68
[PubMed ID: 25200600]
Li J Philip JL Xu X Theccanat T Abdur Razzaque M Akhter SA . β-Arrestins regulate human cardiac fibroblast transformation and collagen synthesis in adverse ventricular remodeling. J Mol Cell Cardiol. 2014 Nov;76:73-83
[PubMed ID: 25134464]
Osaki S Locher MR Lushaj EB Akhter SA Kohmoto T . Functional evaluation of human donation after cardiac death donor hearts using a continuous isolated myocardial perfusion technique: Potential for expansion of the cardiac donor population. J Thorac Cardiovasc Surg. 2014 Sep;148(3):1123-30; discussion 1130
[PubMed ID: 25129607]
Akhter SA Salabat MR Philip JL Valeroso TB Russo MJ Rich JD Jeevanandam V . Durability of De Vega tricuspid valve annuloplasty for severe tricuspid regurgitation during left ventricular assist device implantation. Ann Thorac Surg. 2014 Jul;98(1):81-3
[PubMed ID: 24820391]
Naik A Akhter SA Fedson S Jeevanandam V Rich JD Koyner JL . Acute kidney injury and mortality following ventricular assist device implantation. Am J Nephrol. 2014;39(3):195-203
[PubMed ID: 24556808]
Russo MJ Merlo A Johnson EM Akhter S McCarney S Steiman J Anderson A Jeevanandam V . Transapical approach for mitral valve repair during insertion of a left ventricular assist device. ScientificWorldJournal. 2013;2013:925310
[PubMed ID: 23878531]
Akhter SA . Invited commentary. Ann Thorac Surg. 2013 Apr;95(4):1281
[PubMed ID: 23522195]
Akhter SA . Invited commentary. Ann Thorac Surg. 2013 Jan;95(1):61-2
[PubMed ID: 23272829]
Piao L Fang YH Parikh KS Ryan JJ D'Souza KM Theccanat T Toth PT Pogoriler J Paul J Blaxall BC Akhter SA Archer SL . GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension. Circulation. 2012 Dec 11;126(24):2859-69
[PubMed ID: 23124027]
Iribarne A Burgener JD Hong K Raman J Akhter S Easterwood R Jeevanandam V Russo MJ . Quantifying the incremental cost of complications associated with mitral valve surgery in the United States. J Thorac Cardiovasc Surg. 2012 Apr;143(4):864-72
[PubMed ID: 22424521]
Malhotra R Valuckaite V Staron ML Theccanat T D'Souza KM Alverdy JC Akhter SA . High-molecular-weight polyethylene glycol protects cardiac myocytes from hypoxia- and reoxygenation-induced cell death and preserves ventricular function. Am J Physiol Heart Circ Physiol. 2011 May;300(5):H1733-42
[PubMed ID: 21335476]
Akhter SA . The heart and pericardium. Thorac Surg Clin. 2011 May;21(2):205-17, viii
[PubMed ID: 21477771]
D'Souza KM Malhotra R Philip JL Staron ML Theccanat T Jeevanandam V Akhter SA . G protein-coupled receptor kinase-2 is a novel regulator of collagen synthesis in adult human cardiac fibroblasts. J Biol Chem. 2011 Apr 29;286(17):15507-16
[PubMed ID: 21357420]
Koyner JL Vaidya VS Bennett MR Ma Q Worcester E Akhter SA Raman J Jeevanandam V O'Connor MF Devarajan P Bonventre JV Murray PT . Urinary biomarkers in the clinical prognosis and early detection of acute kidney injury. Clin J Am Soc Nephrol. 2010 Dec;5(12):2154-65
[PubMed ID: 20798258]
Lin E Boire A Hemmige V Husain AN Sorrentino M Nathan S Akhter SA Dickstein J Archer SL . Cardiac tamponade mimicking tuberculous pericarditis as the initial presentation of chronic lymphocytic leukemia in a 58-year-old woman: a case report. J Med Case Rep. 2010 Aug 4;4:246
[PubMed ID: 20684780]
Akhter SA D'Souza KM Malhotra R Staron ML Valeroso TB Fedson SE Anderson AS Raman J Jeevanandam V . Reversal of impaired myocardial beta-adrenergic receptor signaling by continuous-flow left ventricular assist device support. J Heart Lung Transplant. 2010 Jun;29(6):603-9
[PubMed ID: 20202864]