Robert A. Pearce, MD, PhD Print Friendly Page
Chair, Department of AnesthesiologyFaculty, University of Wisconsin School of Medicine and Public Health
Robert A. Pearce, PhD, MD, earned his medical degree from the University of Virginia in Charlottesville, where he also completed his residency.
Specialties
UW Health Clinics
Hospital Affiliation(s)
University of Wisconsin Hospital and Clinics (primary)
Languages Spoken
| English |
| Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000. |
UW School of Medicine and Public Health
| Department of Anesthesiology |
Professional Certifications and Education
| Board Certification |
Anesthesiology
|
| Fellowship |
University of Virginia, Charlottesville
|
| Residency |
University of Virginia, Charlottesville
|
| Internship |
University of Virginia, Charlottesville
|
| Medical School |
University of Virginia, Charlottesville, VA, 1986
|
PubMed Articles
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Dai S Perouansky M Pearce RA .
Isoflurane enhances both fast and slow synaptic inhibition in the hippocampus at amnestic concentrations. Anesthesiology. 2012 Apr;116(4):816-23
[PubMed ID: 22343472]
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Jee JP Parlato MC Perkins MG Mecozzi S Pearce RA .
Exceptionally stable fluorous emulsions for the intravenous delivery of volatile general anesthetics. Anesthesiology. 2012 Mar;116(3):580-5
[PubMed ID: 22354241]
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Johnson RA Simmons KT Fast JP Schroeder CA Pearce RA Albrecht RM Mecozzi S .
Histamine release associated with intravenous delivery of a fluorocarbon-based sevoflurane emulsion in canines. J Pharm Sci. 2011 Jul;100(7):2685-92
[PubMed ID: 21246564]
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Perouansky M Pearce RA .
How we recall (or don't): the hippocampal memory machine and anesthetic amnesia. Can J Anaesth. 2011 Feb;58(2):157-66
[PubMed ID: 21170624]
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Perouansky M Rau V Ford T Oh SI Perkins M Eger EI 2nd Pearce RA .
Slowing of the hippocampal θ rhythm correlates with anesthetic-induced amnesia. Anesthesiology. 2010 Dec;113(6):1299-309
[PubMed ID: 21042201]
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Blake AJ Rodgers FC Bassuener A Hippensteel JA Pearce TM Pearce TR Zarnowska ED Pearce RA Williams JC .
A microfluidic brain slice perfusion chamber for multisite recording using penetrating electrodes. J Neurosci Methods. 2010 May 30;189(1):5-13
[PubMed ID: 20219536]
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Ferrarelli F Massimini M Sarasso S Casali A Riedner BA Angelini G Tononi G Pearce RA .
Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2681-6
[PubMed ID: 20133802]
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Hentschke H Benkwitz C Banks MI Perkins MG Homanics GE Pearce RA .
Altered GABAA,slow inhibition and network oscillations in mice lacking the GABAA receptor beta3 subunit. J Neurophysiol. 2009 Dec;102(6):3643-55
[PubMed ID: 19846622]
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Dai S Perouansky M Pearce RA .
Amnestic concentrations of etomidate modulate GABAA,slow synaptic inhibition in hippocampus. Anesthesiology. 2009 Oct;111(4):766-73
[PubMed ID: 19741493]
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Zarnowska ED Keist R Rudolph U Pearce RA .
GABAA receptor alpha5 subunits contribute to GABAA,slow synaptic inhibition in mouse hippocampus. J Neurophysiol. 2009 Mar;101(3):1179-91
[PubMed ID: 19073796]
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Fast JP Perkins MG Pearce RA Mecozzi S .
Fluoropolymer-based emulsions for the intravenous delivery of sevoflurane. Anesthesiology. 2008 Oct;109(4):651-6
[PubMed ID: 18813044]
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Hentschke H Perkins MG Pearce RA Banks MI .
Muscarinic blockade weakens interaction of gamma with theta rhythms in mouse hippocampus. Eur J Neurosci. 2007 Sep;26(6):1642-56
[PubMed ID: 17880398]
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Perouansky M Hentschke H Perkins M Pearce RA .
Amnesic concentrations of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N) and isoflurane alter hippocampal theta oscillations in vivo. Anesthesiology. 2007 Jun;106(6):1168-76
[PubMed ID: 17525592]
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Johnson MA Weick JP Pearce RA Zhang SC .
Functional neural development from human embryonic stem cells: accelerated synaptic activity via astrocyte coculture. J Neurosci. 2007 Mar 21;27(12):3069-77
[PubMed ID: 17376968]
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Benkwitz C Liao M Laster MJ Sonner JM Eger EI 2nd Pearce RA .
Determination of the EC50 amnesic concentration of etomidate and its diffusion profile in brain tissue: implications for in vitro studies. Anesthesiology. 2007 Jan;106(1):114-23
[PubMed ID: 17197853]
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Hardie JB Pearce RA .
Active and passive membrane properties and intrinsic kinetics shape synaptic inhibition in hippocampal CA1 pyramidal neurons. J Neurosci. 2006 Aug 16;26(33):8559-69
[PubMed ID: 16914682]
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Boileau AJ Pearce RA Czajkowski C .
Tandem subunits effectively constrain GABAA receptor stoichiometry and recapitulate receptor kinetics but are insensitive to GABAA receptor-associated protein. J Neurosci. 2005 Dec 7;25(49):11219-30
[PubMed ID: 16339017]
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Zarnowska ED Pearce RA Saad AA Perouansky M .
The gamma-subunit governs the susceptibility of recombinant gamma-aminobutyric acid type A receptors to block by the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N). Anesth Analg. 2005 Aug;101(2):401-6, table of contents
[PubMed ID: 16037152]
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Perouansky M Banks MI Pearce RA .
The differential effects of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N) and isoflurane on extrasynaptic gamma-aminobutyric acid A receptors. Anesth Analg. 2005 Jun;100(6):1667-73
[PubMed ID: 15920193]
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Yan Y Yang D Zarnowska ED Du Z Werbel B Valliere C Pearce RA Thomson JA Zhang SC .
Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells. 2005 Jun-Jul;23(6):781-90
[PubMed ID: 15917474]
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Benkwitz C Banks MI Pearce RA .
Influence of GABAA receptor gamma2 splice variants on receptor kinetics and isoflurane modulation. Anesthesiology. 2004 Oct;101(4):924-36
[PubMed ID: 15448526]
