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Robert A. Pearce, MD, PhD close
Robert A. Pearce, MD, PhD

Robert A. Pearce, MD, PhD Print Friendly Page

Chair, Department of Anesthesiology
Faculty, University of Wisconsin School of Medicine and Public Health

Robert A. Pearce, PhD, MD, earned his medical degree from the University of Virginia in Charlottesville, where he also completed his residency.

Specialties

Anesthesiology

UW Health Clinics

UW Hospital and Clinics
(608) 263-8100 | (800) 323-8942 | Map

Hospital Affiliation(s)

University of Wisconsin Hospital and Clinics (primary)

Languages Spoken

English
Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

UW School of Medicine and Public Health

Department of Anesthesiology

Professional Certifications and Education

Board Certification Anesthesiology
Fellowship University of Virginia, Charlottesville
Residency University of Virginia, Charlottesville
Internship University of Virginia, Charlottesville
Medical School University of Virginia, Charlottesville, VA, 1986

PubMed Articles
Balakrishnan S Pearce RA . Midazolam and atropine alter theta oscillations in the hippocampal CA1 region by modulating both the somatic and distal dendritic dipoles. Hippocampus. 2014 Oct;24(10):1212-31
[PubMed ID: 24862458]
Burkat PM Lor C Perouansky M Pearce RA . Enhancement of α5-Containing γ-Aminobutyric Acid Type A Receptors by the Nonimmobilizer 1,2-Dichlorohexafluorocyclobutane (F6) Is Abolished by the β3(N265M) Mutation. Anesth Analg. 2014 Sep 10;
[PubMed ID: 25211390]
Goldschen-Ohm MP Haroldson A Jones MV Pearce RA . A nonequilibrium binary elements-based kinetic model for benzodiazepine regulation of GABAA receptors. J Gen Physiol. 2014 Jul;144(1):27-39
[PubMed ID: 24981228]
Dai S Perouansky M Pearce RA . Isoflurane enhances both fast and slow synaptic inhibition in the hippocampus at amnestic concentrations. Anesthesiology. 2012 Apr;116(4):816-23
[PubMed ID: 22343472]
Jee JP Parlato MC Perkins MG Mecozzi S Pearce RA . Exceptionally stable fluorous emulsions for the intravenous delivery of volatile general anesthetics. Anesthesiology. 2012 Mar;116(3):580-5
[PubMed ID: 22354241]
Johnson RA Simmons KT Fast JP Schroeder CA Pearce RA Albrecht RM Mecozzi S . Histamine release associated with intravenous delivery of a fluorocarbon-based sevoflurane emulsion in canines. J Pharm Sci. 2011 Jul;100(7):2685-92
[PubMed ID: 21246564]
Perouansky M Pearce RA . How we recall (or don't): the hippocampal memory machine and anesthetic amnesia. Can J Anaesth. 2011 Feb;58(2):157-66
[PubMed ID: 21170624]
Perouansky M Rau V Ford T Oh SI Perkins M Eger EI 2nd Pearce RA . Slowing of the hippocampal θ rhythm correlates with anesthetic-induced amnesia. Anesthesiology. 2010 Dec;113(6):1299-309
[PubMed ID: 21042201]
Blake AJ Rodgers FC Bassuener A Hippensteel JA Pearce TM Pearce TR Zarnowska ED Pearce RA Williams JC . A microfluidic brain slice perfusion chamber for multisite recording using penetrating electrodes. J Neurosci Methods. 2010 May 30;189(1):5-13
[PubMed ID: 20219536]
Ferrarelli F Massimini M Sarasso S Casali A Riedner BA Angelini G Tononi G Pearce RA . Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2681-6
[PubMed ID: 20133802]
Hentschke H Benkwitz C Banks MI Perkins MG Homanics GE Pearce RA . Altered GABAA,slow inhibition and network oscillations in mice lacking the GABAA receptor beta3 subunit. J Neurophysiol. 2009 Dec;102(6):3643-55
[PubMed ID: 19846622]
Dai S Perouansky M Pearce RA . Amnestic concentrations of etomidate modulate GABAA,slow synaptic inhibition in hippocampus. Anesthesiology. 2009 Oct;111(4):766-73
[PubMed ID: 19741493]
Zarnowska ED Keist R Rudolph U Pearce RA . GABAA receptor alpha5 subunits contribute to GABAA,slow synaptic inhibition in mouse hippocampus. J Neurophysiol. 2009 Mar;101(3):1179-91
[PubMed ID: 19073796]
Fast JP Perkins MG Pearce RA Mecozzi S . Fluoropolymer-based emulsions for the intravenous delivery of sevoflurane. Anesthesiology. 2008 Oct;109(4):651-6
[PubMed ID: 18813044]
Hentschke H Perkins MG Pearce RA Banks MI . Muscarinic blockade weakens interaction of gamma with theta rhythms in mouse hippocampus. Eur J Neurosci. 2007 Sep;26(6):1642-56
[PubMed ID: 17880398]
Perouansky M Hentschke H Perkins M Pearce RA . Amnesic concentrations of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N) and isoflurane alter hippocampal theta oscillations in vivo. Anesthesiology. 2007 Jun;106(6):1168-76
[PubMed ID: 17525592]
Johnson MA Weick JP Pearce RA Zhang SC . Functional neural development from human embryonic stem cells: accelerated synaptic activity via astrocyte coculture. J Neurosci. 2007 Mar 21;27(12):3069-77
[PubMed ID: 17376968]
Benkwitz C Liao M Laster MJ Sonner JM Eger EI 2nd Pearce RA . Determination of the EC50 amnesic concentration of etomidate and its diffusion profile in brain tissue: implications for in vitro studies. Anesthesiology. 2007 Jan;106(1):114-23
[PubMed ID: 17197853]
Hardie JB Pearce RA . Active and passive membrane properties and intrinsic kinetics shape synaptic inhibition in hippocampal CA1 pyramidal neurons. J Neurosci. 2006 Aug 16;26(33):8559-69
[PubMed ID: 16914682]
Boileau AJ Pearce RA Czajkowski C . Tandem subunits effectively constrain GABAA receptor stoichiometry and recapitulate receptor kinetics but are insensitive to GABAA receptor-associated protein. J Neurosci. 2005 Dec 7;25(49):11219-30
[PubMed ID: 16339017]