Ozioma C. Okonkwo, PhD Print Friendly PageFaculty, University of Wisconsin School of Medicine and Public Health
Ozioma C. Okonkwo, PhD, is an Assistant Professor of Medicine at the University of Wisconsin School of Medicine and Public Health. He specializes in the neuropsychological evaluation of geriatric cognitive disorders, especially those due to suspected Alzheimer's disease.
UW Health Clinics
UW School of Medicine and Public Health
|Department of Medicine|
Professional Certifications and Education
Licensed Clinical Psychologist
NIH T32 AG027668, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD
VA Advanced Fellowship in Geriatrics, the Geriatric Research, Education, and Clinical Center (GRECC), William S. Middleton Memorial Veterans Hospital, Madison, WI
Warren Alpert Medical School of Brown University, Providence, RI
University of Alabama, Birmingham, AL, 2009
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Dr. Okonkwo's research focuses on clarifying how alterations in the brain and other biomolecules (such as cerebrospinal fluid β-amyloid) place some cognitively-normal individuals on a pernicious trajectory that culminates in probable Alzheimer's disease. In this context, Dr. Okonkwo is also interested in discovering new knowledge concerning the modulation of the link between brain changes and cognitive decline by both modifiable (e.g., cognitively stimulating activities, physical exercise) and non-modifiable (e.g., genetic vulnerability) factors.
Okonkwo OC Simons A Nichani J .
Paediatric airway foreign body - The human factors influencing patient safety in our hospitals. Int J Pediatr Otorhinolaryngol. 2016 Dec;91:100-104
[PubMed ID: 27863620]
Law LL Schultz SA Boots EA Einerson JA Dougherty RJ Oh JM Korcarz CE Edwards DF Koscik RL Dowling NM Gallagher CL Bendlin BB Carlsson CM Asthana S Hermann BP Sager MA Johnson SC Cook DB Stein JH Okonkwo OC .
Chronotropic Response and Cognitive Function in a Cohort at Risk for Alzheimer's Disease. J Alzheimers Dis. 2016 Dec 1;
[PubMed ID: 27911299]
Wang J Cunningham R Zetterberg H Asthana S Carlsson C Okonkwo O Li L .
Label-free quantitative comparison of cerebrospinal fluid glycoproteins and endogenous peptides in subjects with Alzheimer's disease, mild cognitive impairment, and healthy individuals. Proteomics Clin Appl. 2016 Dec;10(12):1225-1241
[PubMed ID: 27863112]
Okonkwo OC Asthana S .
Dementia Trends in the United States: Read Up and Weigh In. JAMA Intern Med. 2016 Nov 21;
[PubMed ID: 27893015]
Darst BF Koscik RL Racine AM Oh JM Krause RA Carlsson CM Zetterberg H Blennow K Christian BT Bendlin BB Okonkwo OC Hogan KJ Hermann BP Sager MA Asthana S Johnson SC Engelman CD .
Pathway-Specific Polygenic Risk Scores as Predictors of Amyloid-β Deposition and Cognitive Function in a Sample at Increased Risk for Alzheimer's Disease. J Alzheimers Dis. 2016 Nov 19;55(2):473-484
[PubMed ID: 27662287]
Koscik RL Berman SE Clark LR Mueller KD Okonkwo OC Gleason CE Hermann BP Sager MA Johnson SC .
Intraindividual Cognitive Variability in Middle Age Predicts Cognitive Impairment 8-10 Years Later: Results from the Wisconsin Registry for Alzheimer's Prevention. J Int Neuropsychol Soc. 2016 Nov;22(10):1016-1025
[PubMed ID: 27903330]
Dean DC 3rd Sojkova J Hurley S Kecskemeti S Okonkwo O Bendlin BB Theisen F Johnson SC Alexander AL Gallagher CL .
Alterations of Myelin Content in Parkinson's Disease: A Cross-Sectional Neuroimaging Study. PLoS One. 2016 Oct 5;11(10):e0163774
[PubMed ID: 27706215]
Yang R Sabharwal V Okonkwo OS Shlykova N Tong R Lin LY Wang W Guo S Rosowski JJ Pelton SI Kohane DS .
Treatment of otitis media by transtympanic delivery of antibiotics. Sci Transl Med. 2016 Sep 14;8(356):356ra120
[PubMed ID: 27629487]
Nzegwu MA Ohegbulam S Ndubuisi C Okwunodulu O Okorie E Nkwerem S Okonkwo O Aniume O Nnamani S Nwokoro O Eni A Nwideyi I Nzegwu V .
Cerebellar Liponeurocytoma: A Novel Report from Nigeria in a 6-Year-Old Girl, and Review of Literature. Rare Tumors. 2016 Sep 5;8(3):6240
[PubMed ID: 27746877]
Racine AM Koscik RL Berman SE Nicholas CR Clark LR Okonkwo OC Rowley HA Asthana S Bendlin BB Blennow K Zetterberg H Gleason CE Carlsson CM Johnson SC .
Biomarker clusters are differentially associated with longitudinal cognitive decline in late midlife. Brain. 2016 Aug;139(Pt 8):2261-74
[PubMed ID: 27324877]
Clark LR Racine AM Koscik RL Okonkwo OC Engelman CD Carlsson CM Asthana S Bendlin BB Chappell R Nicholas CR Rowley HA Oh JM Hermann BP Sager MA Christian BT Johnson SC .
Beta-amyloid and cognitive decline in late middle age: Findings from the Wisconsin Registry for Alzheimer's Prevention study. Alzheimers Dement. 2016 Jul;12(7):805-14
[PubMed ID: 26806386]
Merluzzi AP Dean DC 3rd Adluru N Suryawanshi GS Okonkwo OC Oh JM Hermann BP Sager MA Asthana S Zhang H Johnson SC Alexander AL Bendlin BB .
Age-dependent differences in brain tissue microstructure assessed with neurite orientation dispersion and density imaging. Neurobiol Aging. 2016 Jul;43:79-88
[PubMed ID: 27255817]
Clark LR Koscik RL Nicholas CR Okonkwo OC Engelman CD Bratzke LC Hogan KJ Mueller KD Bendlin BB Carlsson CM Asthana S Sager MA Hermann BP Johnson SC .
Mild Cognitive Impairment in Late Middle Age in the Wisconsin Registry for Alzheimer's Prevention Study: Prevalence and Characteristics Using Robust and Standard Neuropsychological Normative Data. Arch Clin Neuropsychol. 2016 May 8;
[PubMed ID: 27193363]
Dougherty R Boots E Schultz S Johnson S Okonkwo O Cook DB .
Influence Of VO2peak Criteria On Aging And Alzheimer's Research: 2932 June 3 1: 30 PM - 1: 45 PM. Med Sci Sports Exerc. 2016 May;48(5 Suppl 1):822
[PubMed ID: 27361501]
Dougherty RJ Ellingson LD Schultz SA Boots EA Meyer JD Lindheimer JB Van Riper S Stegner AJ Edwards DF Oh JM Koscik RL Dowling MN Gallagher CL Carlsson CM Rowley HA Bendlin BB Asthana S Hermann BP Sager MA Johnson SC Okonkwo OC Cook DB .
Meeting physical activity recommendations may be protective against temporal lobe atrophy in older adults at risk for Alzheimer's disease. Alzheimers Dement (Amst). 2016 Apr 9;4:14-7
[PubMed ID: 27489874]
Abimbola S Molemodile SK Okonkwo OA Negin J Jan S Martiniuk AL .
'The government cannot do it all alone': realist analysis of the minutes of community health committee meetings in Nigeria. Health Policy Plan. 2016 Apr;31(3):332-45
[PubMed ID: 26210167]
Ly M Adluru N Destiche DJ Lu SY Oh JM Hoscheidt SM Alexander AL Okonkwo OC Rowley HA Sager MA Johnson SC Bendlin BB .
Fornix Microstructure and Memory Performance Is Associated with Altered Neural Connectivity during Episodic Recognition. J Int Neuropsychol Soc. 2016 Feb;22(2):191-204
[PubMed ID: 26888616]
Racine AM Koscik RL Nicholas CR Clark LR Okonkwo OC Oh JM Hillmer AT Murali D Barnhart TE Betthauser TJ Gallagher CL Rowley HA Dowling NM Asthana S Bendlin BB Blennow K Zetterberg H Carlsson CM Christian BT Johnson SC .
Cerebrospinal fluid ratios with Aβ42 predict preclinical brain β-amyloid accumulation. Alzheimers Dement (Amst). 2016;2:27-38
[PubMed ID: 26955655]
Melah KE Lu SY Hoscheidt SM Alexander AL Adluru N Destiche DJ Carlsson CM Zetterberg H Blennow K Okonkwo OC Gleason CE Dowling NM Bratzke LC Rowley HA Sager MA Asthana S Johnson SC Bendlin BB .
Cerebrospinal Fluid Markers of Alzheimer's Disease Pathology and Microglial Activation are Associated with Altered White Matter Microstructure in Asymptomatic Adults at Risk for Alzheimer's Disease. J Alzheimers Dis. 2016;50(3):873-86
[PubMed ID: 26836182]
Okoye O Okonkwo O Oderinlo O Hassan K Ijasan A .
Bilateral concomitant intravitreal anti-vascular endothelial growth factor injection: Experience in a Nigerian tertiary private eye care facility. Niger J Clin Pract. 2016 Jul-Aug;19(4):544-8
[PubMed ID: 27251975]