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Ozioma C. Okonkwo, PhD close
Ozioma C. Okonkwo, PhD

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Ozioma C. Okonkwo, PhD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Ozioma C. Okonkwo, PhD, is an Assistant Professor of Medicine at the University of Wisconsin School of Medicine and Public Health. He specializes in the neuropsychological evaluation of geriatric cognitive disorders, especially those due to suspected Alzheimer's disease.


Geriatrics (Specialty Care)

UW Health Clinics

University Station Clinic
(608) 263-7740 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital (primary)

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Licenses Licensed Clinical Psychologist

NIH T32 AG027668, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD

VA Advanced Fellowship in Geriatrics, the Geriatric Research, Education, and Clinical Center (GRECC), William S. Middleton Memorial Veterans Hospital, Madison, WI

Internship Warren Alpert Medical School of Brown University, Providence, RI
Medical School University of Alabama, Birmingham, AL, 2009

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Programs & Conditions


Dr. Okonkwo's research focuses on clarifying how alterations in the brain and other biomolecules (such as cerebrospinal fluid β-amyloid) place some cognitively-normal individuals on a pernicious trajectory that culminates in probable Alzheimer's disease. In this context, Dr. Okonkwo is also interested in discovering new knowledge concerning the modulation of the link between brain changes and cognitive decline by both modifiable (e.g., cognitively stimulating activities, physical exercise) and non-modifiable (e.g., genetic vulnerability) factors.

PubMed Articles
Sprecher KE Koscik RL Carlsson CM Zetterberg H Blennow K Okonkwo OC Sager MA Asthana S Johnson SC Benca RM Bendlin BB . Poor sleep is associated with CSF biomarkers of amyloid pathology in cognitively normal adults. Neurology. 2017 Aug 1;89(5):445-453
[PubMed ID: 28679595]
Lassen-Greene CL Steward K Okonkwo O Porter E Crowe M Vance DE Griffith HR Ball K Marson DC Wadley VG . Mild Cognitive Impairment and Changes in Everyday Function Over Time: The Importance of Evaluating Both Speed and Accuracy. J Geriatr Psychiatry Neurol. 2017 Jul;30(4):220-227
[PubMed ID: 28639877]
Boots EA Schultz SA Clark LR Racine AM Darst BF Koscik RL Carlsson CM Gallagher CL Hogan KJ Bendlin BB Asthana S Sager MA Hermann BP Christian BT Dubal DB Engelman CD Johnson SC Okonkwo OC . BDNF Val66Met predicts cognitive decline in the Wisconsin Registry for Alzheimer's Prevention. Neurology. 2017 May 30;88(22):2098-2106
[PubMed ID: 28468845]
Schultz SA Boots EA Darst BF Zetterberg H Blennow K Edwards DF Koscik RL Carlsson CM Gallagher CL Bendlin BB Asthana S Sager MA Hogan KJ Hermann BP Cook DB Johnson SC Engelman CD Okonkwo OC . Cardiorespiratory fitness alters the influence of a polygenic risk score on biomarkers of AD. Neurology. 2017 Apr 25;88(17):1650-1658
[PubMed ID: 28341646]
Okonkwo OC Vemuri P . Stemming the Alzheimer tsunami: introduction to the special issue on reserve and resilience in Alzheimer's disease. Brain Imaging Behav. 2017 Apr;11(2):301-303
[PubMed ID: 28116651]
Hoy AR Ly M Carlsson CM Okonkwo OC Zetterberg H Blennow K Sager MA Asthana S Johnson SC Alexander AL Bendlin BB . Microstructural white matter alterations in preclinical Alzheimer's disease detected using free water elimination diffusion tensor imaging. PLoS One. 2017;12(3):e0173982
[PubMed ID: 28291839]
Dougherty RJ Schultz SA Boots EA Ellingson LD Meyer JD Van Riper S Stegner AJ Edwards DF Oh JM Einerson J Korcarz CE Koscik RL Dowling MN Gallagher CL Carlsson CM Rowley HA Bendlin BB Asthana S Hermann BP Sager MA Stein JH Johnson SC Okonkwo OC Cook DB . Relationships between cardiorespiratory fitness, hippocampal volume, and episodic memory in a population at risk for Alzheimer's disease. Brain Behav. 2017 Mar;7(3):e00625
[PubMed ID: 28293467]
Oderinlo O Hassan AO Oluyadi FO Ogunro AO Okonkwo ON Ulaikere MO Ashano O . Refractive aim and visual outcome after phacoemulsification: A 2-year review from a Tertiary Private Eye Hospital in Sub-Saharan Africa. Niger J Clin Pract. 2017 Feb;20(2):147-152
[PubMed ID: 28091428]
Dougherty RJ Schultz SA Kirby TK Boots EA Oh JM Edwards D Gallagher CL Carlsson CM Bendlin BB Asthana S Sager MA Hermann BP Christian BT Johnson SC Cook DB Okonkwo OC . Moderate Physical Activity is Associated with Cerebral Glucose Metabolism in Adults at Risk for Alzheimer's Disease. J Alzheimers Dis. 2017;58(4):1089-1097
[PubMed ID: 28527205]
Law LL Schultz SA Boots EA Einerson JA Dougherty RJ Oh JM Korcarz CE Edwards DF Koscik RL Dowling NM Gallagher CL Bendlin BB Carlsson CM Asthana S Hermann BP Sager MA Johnson SC Cook DB Stein JH Okonkwo OC . Chronotropic Response and Cognitive Function in a Cohort at Risk for Alzheimer's Disease. J Alzheimers Dis. 2017;56(1):351-359
[PubMed ID: 27911299]
Darst BF Koscik RL Racine AM Oh JM Krause RA Carlsson CM Zetterberg H Blennow K Christian BT Bendlin BB Okonkwo OC Hogan KJ Hermann BP Sager MA Asthana S Johnson SC Engelman CD . Pathway-Specific Polygenic Risk Scores as Predictors of Amyloid-β Deposition and Cognitive Function in a Sample at Increased Risk for Alzheimer's Disease. J Alzheimers Dis. 2017;55(2):473-484
[PubMed ID: 27662287]
Okonkwo OC Asthana S . Dementia Trends in the United States: Read Up and Weigh In. JAMA Intern Med. 2017 Jan 1;177(1):58-60
[PubMed ID: 27893015]
Golnik KC Law JC Ramasamy K Mahmoud TH Okonkwo ON Singh J Arevalo JF . The Ophthalmology Surgical Competency Assessment Rubric for Vitrectomy. Retina. 2016 Dec 19;
[PubMed ID: 28613227]
Okonkwo OC Simons A Nichani J . Paediatric airway foreign body - The human factors influencing patient safety in our hospitals. Int J Pediatr Otorhinolaryngol. 2016 Dec;91:100-104
[PubMed ID: 27863620]
Wang J Cunningham R Zetterberg H Asthana S Carlsson C Okonkwo O Li L . Label-free quantitative comparison of cerebrospinal fluid glycoproteins and endogenous peptides in subjects with Alzheimer's disease, mild cognitive impairment, and healthy individuals. Proteomics Clin Appl. 2016 Dec;10(12):1225-1241
[PubMed ID: 27863112]
Koscik RL Berman SE Clark LR Mueller KD Okonkwo OC Gleason CE Hermann BP Sager MA Johnson SC . Intraindividual Cognitive Variability in Middle Age Predicts Cognitive Impairment 8-10 Years Later: Results from the Wisconsin Registry for Alzheimer's Prevention. J Int Neuropsychol Soc. 2016 Nov;22(10):1016-1025
[PubMed ID: 27903330]
Dean DC 3rd Sojkova J Hurley S Kecskemeti S Okonkwo O Bendlin BB Theisen F Johnson SC Alexander AL Gallagher CL . Alterations of Myelin Content in Parkinson's Disease: A Cross-Sectional Neuroimaging Study. PLoS One. 2016;11(10):e0163774
[PubMed ID: 27706215]
Zuelsdorff ML Koscik RL Okonkwo OC Peppard PE Hermann BP Sager MA Johnson SC Engelman CD . Reliability of a Novel Social Activity Questionnaire. J Aging Health. 2016 Oct 1;:898264316674812
[PubMed ID: 28553788]
Yang R Sabharwal V Okonkwo OS Shlykova N Tong R Lin LY Wang W Guo S Rosowski JJ Pelton SI Kohane DS . Treatment of otitis media by transtympanic delivery of antibiotics. Sci Transl Med. 2016 Sep 14;8(356):356ra120
[PubMed ID: 27629487]
Nzegwu MA Ohegbulam S Ndubuisi C Okwunodulu O Okorie E Nkwerem S Okonkwo O Aniume O Nnamani S Nwokoro O Eni A Nwideyi I Nzegwu V . Cerebellar Liponeurocytoma: A Novel Report from Nigeria in a 6-Year-Old Girl, and Review of Literature. Rare Tumors. 2016 Sep 5;8(3):6240
[PubMed ID: 27746877]