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Ozioma C. Okonkwo, PhD close
Ozioma C. Okonkwo, PhD

Ozioma C. Okonkwo, PhD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Ozioma C. Okonkwo, PhD, is an Assistant Professor of Medicine at the University of Wisconsin School of Medicine and Public Health. He specializes in the neuropsychological evaluation of geriatric cognitive disorders, especially those due to suspected Alzheimer's disease.

Specialties

Geriatrics (Specialty Care)

UW Health Clinics

University Station Clinic
(608) 263-7740 | (800) 323-8942 | Map

Hospital Affiliation(s)

University of Wisconsin Hospital and Clinics (primary)

Languages Spoken

English
Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Licenses Licensed Clinical Psychologist
Fellowship

NIH T32 AG027668, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD

VA Advanced Fellowship in Geriatrics, the Geriatric Research, Education, and Clinical Center (GRECC), William S. Middleton Memorial Veterans Hospital, Madison, WI


Internship Warren Alpert Medical School of Brown University, Providence, RI
Medical School University of Alabama, Birmingham, AL, 2009

Programs & Conditions

Research

Dr. Okonkwo's research focuses on clarifying how alterations in the brain and other biomolecules (such as cerebrospinal fluid β-amyloid) place some cognitively-normal individuals on a pernicious trajectory that culminates in probable Alzheimer's disease. In this context, Dr. Okonkwo is also interested in discovering new knowledge concerning the modulation of the link between brain changes and cognitive decline by both modifiable (e.g., cognitively stimulating activities, physical exercise) and non-modifiable (e.g., genetic vulnerability) factors.


PubMed Articles
Okonkwo OC . At the crossroads of preclinical AD and normal brain ageing. Lancet Neurol. 2014 Sep 4;
[PubMed ID: 25201513]
Li CT Palotti M Holden JE Oh J Okonkwo O Christian BT Bendlin BB Buyan-Dent L Harding SJ Stone CK DeJesus OT Nickles RJ Gallagher CL . A dual-tracer study of extrastriatal 6-[18F]fluoro-m-tyrosine and 6-[18F]-fluoro-L-dopa uptake in Parkinson's disease. Synapse. 2014 Aug;68(8):325-31
[PubMed ID: 24710997]
Gan A Okonkwo O . The use of Google drive in clinical audit. Br J Hosp Med (Lond). 2014 Jul;75(7):397-8, 400-1
[PubMed ID: 25040519]
Sacktor N Nakasujja N Redd AD Manucci J Laeyendecker O Wendel SK Porcella SF Martens C Bruno D Skolasky RL Okonkwo OC Robertson K Musisi S Katabira E Quinn TC . HIV subtype is not associated with dementia among individuals with moderate and advanced immunosuppression in Kampala, Uganda. Metab Brain Dis. 2014 Jun;29(2):261-8
[PubMed ID: 24515303]
Kim WH Singh V Chung MK Hinrichs C Pachauri D Okonkwo OC Johnson SC . Multi-resolutional shape features via non-Euclidean wavelets: applications to statistical analysis of cortical thickness. Neuroimage. 2014 Jun;93 Pt 1:107-23
[PubMed ID: 24614060]
Okonkwo OC Xu G Oh JM Dowling NM Carlsson CM Gallagher CL Birdsill AC Palotti M Wharton W Hermann BP LaRue A Bendlin BB Rowley HA Asthana S Sager MA Johnson SC . Cerebral blood flow is diminished in asymptomatic middle-aged adults with maternal history of Alzheimer's disease. Cereb Cortex. 2014 Apr;24(4):978-88
[PubMed ID: 23236200]
Okonkwo OC Oh JM Koscik R Jonaitis E Cleary CA Dowling NM Bendlin BB Larue A Hermann BP Barnhart TE Murali D Rowley HA Carlsson CM Gallagher CL Asthana S Sager MA Christian BT Johnson SC . Amyloid burden, neuronal function, and cognitive decline in middle-aged adults at risk for Alzheimer's disease. J Int Neuropsychol Soc. 2014 Apr;20(4):422-33
[PubMed ID: 24621494]
Birdsill AC Koscik RL Jonaitis EM Johnson SC Okonkwo OC Hermann BP Larue A Sager MA Bendlin BB . Regional white matter hyperintensities: aging, Alzheimer's disease risk, and cognitive function. Neurobiol Aging. 2014 Apr;35(4):769-76
[PubMed ID: 24199958]
Johnson SC Christian BT Okonkwo OC Oh JM Harding S Xu G Hillmer AT Wooten DW Murali D Barnhart TE Hall LT Racine AM Klunk WE Mathis CA Bendlin BB Gallagher CL Carlsson CM Rowley HA Hermann BP Dowling NM Asthana S Sager MA . Amyloid burden and neural function in people at risk for Alzheimer's Disease. Neurobiol Aging. 2014 Mar;35(3):576-84
[PubMed ID: 24269021]
Timko BP Arruebo M Shankarappa SA McAlvin JB Okonkwo OS Mizrahi B Stefanescu CF Gomez L Zhu J Zhu A Santamaria J Langer R Kohane DS . Near-infrared-actuated devices for remotely controlled drug delivery. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1349-54
[PubMed ID: 24474759]
Koscik RL La Rue A Jonaitis EM Okonkwo OC Johnson SC Bendlin BB Hermann BP Sager MA . Emergence of mild cognitive impairment in late middle-aged adults in the wisconsin registry for Alzheimer's prevention. Dement Geriatr Cogn Disord. 2014;38(1-2):16-30
[PubMed ID: 24556849]
Lugo JN Smith GD Arbuckle EP White J Holley AJ Floruta CM Ahmed N Gomez MC Okonkwo O . Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins. Front Mol Neurosci. 2014;7:27
[PubMed ID: 24795561]
Adluru N Destiche DJ Lu SY Doran ST Birdsill AC Melah KE Okonkwo OC Alexander AL Dowling NM Johnson SC Sager MA Bendlin BB . White matter microstructure in late middle-age: Effects of apolipoprotein E4 and parental family history of Alzheimer's disease. Neuroimage Clin. 2014;4:730-42
[PubMed ID: 24936424]
Racine AM Adluru N Alexander AL Christian BT Okonkwo OC Oh J Cleary CA Birdsill A Hillmer AT Murali D Barnhart TE Gallagher CL Carlsson CM Rowley HA Dowling NM Asthana S Sager MA Bendlin BB Johnson SC . Associations between white matter microstructure and amyloid burden in preclinical Alzheimer's disease: A multimodal imaging investigation. Neuroimage Clin. 2014;4:604-14
[PubMed ID: 24936411]
Griffith HR Okonkwo OC Stewart CC Stoeckel LE Hollander JA Elgin JM Harrell LE Brockington JC Clark DG Ball KK Owsley C Marson DC Wadley VG . Lower hippocampal volume predicts decrements in lane control among drivers with amnestic mild cognitive impairment. J Geriatr Psychiatry Neurol. 2013 Dec;26(4):259-66
[PubMed ID: 24212246]
Stoeckel LE Stewart CC Griffith HR Triebel K Okonkwo OC den Hollander JA Martin RC Belue K Copeland JN Harrell LE Brockington JC Clark DG Marson DC . MRI volume of the medial frontal cortex predicts financial capacity in patients with mild Alzheimer's disease. Brain Imaging Behav. 2013 Sep;7(3):282-92
[PubMed ID: 23504597]
Birdsill AC Carlsson CM Willette AA Okonkwo OC Johnson SC Xu G Oh JM Gallagher CL Koscik RL Jonaitis EM Hermann BP LaRue A Rowley HA Asthana S Sager MA Bendlin BB . Low cerebral blood flow is associated with lower memory function in metabolic syndrome. Obesity (Silver Spring). 2013 Jul;21(7):1313-20
[PubMed ID: 23687103]
Wang X Okonkwo O Kebaara BW . Physiological basis of copper tolerance of Saccharomyces cerevisiae nonsense-mediated mRNA decay mutants. Yeast. 2013 May;30(5):179-90
[PubMed ID: 23450501]
Okonkwo OW Batwara R Granja I Asplin JR Goldfarb DS . A pilot study of the effect of sodium thiosulfate on urinary lithogenicity and associated metabolic acid load in non-stone formers and stone formers with hypercalciuria. PLoS One. 2013;8(4):e60380
[PubMed ID: 23593205]
Gallagher C Bell B Bendlin B Palotti M Okonkwo O Sodhi A Wong R Buyan-Dent L Johnson S Willette A Harding S Ninman N Kastman E Alexander A . White matter microstructural integrity and executive function in Parkinson's disease. J Int Neuropsychol Soc. 2013 Mar;19(3):349-54
[PubMed ID: 23321049]