Ozioma C. Okonkwo, PhD Print Friendly PageFaculty, University of Wisconsin School of Medicine and Public Health
Ozioma C. Okonkwo, PhD, is an Assistant Professor of Medicine at the University of Wisconsin School of Medicine and Public Health. He specializes in the neuropsychological evaluation of geriatric cognitive disorders, especially those due to suspected Alzheimer's disease.
UW Health Clinics
UW School of Medicine and Public Health
|Department of Medicine|
Professional Certifications and Education
Licensed Clinical Psychologist
NIH T32 AG027668, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD
VA Advanced Fellowship in Geriatrics, the Geriatric Research, Education, and Clinical Center (GRECC), William S. Middleton Memorial Veterans Hospital, Madison, WI
Warren Alpert Medical School of Brown University, Providence, RI
University of Alabama, Birmingham, AL, 2009
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Dr. Okonkwo's research focuses on clarifying how alterations in the brain and other biomolecules (such as cerebrospinal fluid β-amyloid) place some cognitively-normal individuals on a pernicious trajectory that culminates in probable Alzheimer's disease. In this context, Dr. Okonkwo is also interested in discovering new knowledge concerning the modulation of the link between brain changes and cognitive decline by both modifiable (e.g., cognitively stimulating activities, physical exercise) and non-modifiable (e.g., genetic vulnerability) factors.
Okonkwo OC Schultz SA Oh JM Larson J Edwards D Cook D Koscik R Gallagher CL Dowling NM Carlsson CM Bendlin BB LaRue A Rowley HA Christian BT Asthana S Hermann BP Johnson SC Sager MA .
Physical activity attenuates age-related biomarker alterations in preclinical AD. Neurology. 2014 Nov 4;83(19):1753-60
[PubMed ID: 25298312]
Schultz SA Larson J Oh J Koscik R Dowling MN Gallagher CL Carlsson CM Rowley HA Bendlin BB Asthana S Hermann BP Johnson SC Sager M LaRue A Okonkwo OC .
Participation in cognitively-stimulating activities is associated with brain structure and cognitive function in preclinical Alzheimer's disease. Brain Imaging Behav. 2014 Oct 31;
[PubMed ID: 25358750]
Nicholas CR Okonkwo OC Bendlin BB Oh JM Asthana S Rowley HA Hermann B Sager MA Johnson SC .
Posteromedial hyperactivation during episodic recognition among people with memory decline: findings from the WRAP study. Brain Imaging Behav. 2014 Oct 21;
[PubMed ID: 25332108]
Boots EA Schultz SA Oh JM Larson J Edwards D Cook D Koscik RL Dowling MN Gallagher CL Carlsson CM Rowley HA Bendlin BB LaRue A Asthana S Hermann BP Sager MA Johnson SC Okonkwo OC .
Cardiorespiratory fitness is associated with brain structure, cognition, and mood in a middle-aged cohort at risk for Alzheimer's disease. Brain Imaging Behav. 2014 Oct 16;
[PubMed ID: 25319359]
Nowrangi MA Okonkwo O Lyketsos C Oishi K Mori S Albert M Mielke MM .
Atlas-Based Diffusion Tensor Imaging Correlates of Executive Function. J Alzheimers Dis. 2014 Oct 15;
[PubMed ID: 25318544]
Okonkwo OC .
At the crossroads of preclinical AD and normal brain ageing. Lancet Neurol. 2014 Oct;13(10):965-6
[PubMed ID: 25201513]
Li CT Palotti M Holden JE Oh J Okonkwo O Christian BT Bendlin BB Buyan-Dent L Harding SJ Stone CK DeJesus OT Nickles RJ Gallagher CL .
A dual-tracer study of extrastriatal 6-[18F]fluoro-m-tyrosine and 6-[18F]-fluoro-L-dopa uptake in Parkinson's disease. Synapse. 2014 Aug;68(8):325-31
[PubMed ID: 24710997]
Gan A Okonkwo O .
The use of Google Drive in clinical audit. Br J Hosp Med (Lond). 2014 Jul;75(7):397-8, 400-1
[PubMed ID: 25040519]
Sacktor N Nakasujja N Redd AD Manucci J Laeyendecker O Wendel SK Porcella SF Martens C Bruno D Skolasky RL Okonkwo OC Robertson K Musisi S Katabira E Quinn TC .
HIV subtype is not associated with dementia among individuals with moderate and advanced immunosuppression in Kampala, Uganda. Metab Brain Dis. 2014 Jun;29(2):261-8
[PubMed ID: 24515303]
Kim WH Singh V Chung MK Hinrichs C Pachauri D Okonkwo OC Johnson SC .
Multi-resolutional shape features via non-Euclidean wavelets: applications to statistical analysis of cortical thickness. Neuroimage. 2014 Jun;93 Pt 1:107-23
[PubMed ID: 24614060]
Okonkwo OC Xu G Oh JM Dowling NM Carlsson CM Gallagher CL Birdsill AC Palotti M Wharton W Hermann BP LaRue A Bendlin BB Rowley HA Asthana S Sager MA Johnson SC .
Cerebral blood flow is diminished in asymptomatic middle-aged adults with maternal history of Alzheimer's disease. Cereb Cortex. 2014 Apr;24(4):978-88
[PubMed ID: 23236200]
Okonkwo OC Oh JM Koscik R Jonaitis E Cleary CA Dowling NM Bendlin BB Larue A Hermann BP Barnhart TE Murali D Rowley HA Carlsson CM Gallagher CL Asthana S Sager MA Christian BT Johnson SC .
Amyloid burden, neuronal function, and cognitive decline in middle-aged adults at risk for Alzheimer's disease. J Int Neuropsychol Soc. 2014 Apr;20(4):422-33
[PubMed ID: 24621494]
Birdsill AC Koscik RL Jonaitis EM Johnson SC Okonkwo OC Hermann BP Larue A Sager MA Bendlin BB .
Regional white matter hyperintensities: aging, Alzheimer's disease risk, and cognitive function. Neurobiol Aging. 2014 Apr;35(4):769-76
[PubMed ID: 24199958]
Johnson SC Christian BT Okonkwo OC Oh JM Harding S Xu G Hillmer AT Wooten DW Murali D Barnhart TE Hall LT Racine AM Klunk WE Mathis CA Bendlin BB Gallagher CL Carlsson CM Rowley HA Hermann BP Dowling NM Asthana S Sager MA .
Amyloid burden and neural function in people at risk for Alzheimer's Disease. Neurobiol Aging. 2014 Mar;35(3):576-84
[PubMed ID: 24269021]
Timko BP Arruebo M Shankarappa SA McAlvin JB Okonkwo OS Mizrahi B Stefanescu CF Gomez L Zhu J Zhu A Santamaria J Langer R Kohane DS .
Near-infrared-actuated devices for remotely controlled drug delivery. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1349-54
[PubMed ID: 24474759]
Koscik RL La Rue A Jonaitis EM Okonkwo OC Johnson SC Bendlin BB Hermann BP Sager MA .
Emergence of mild cognitive impairment in late middle-aged adults in the wisconsin registry for Alzheimer's prevention. Dement Geriatr Cogn Disord. 2014;38(1-2):16-30
[PubMed ID: 24556849]
Lugo JN Smith GD Arbuckle EP White J Holley AJ Floruta CM Ahmed N Gomez MC Okonkwo O .
Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins. Front Mol Neurosci. 2014;7:27
[PubMed ID: 24795561]
Adluru N Destiche DJ Lu SY Doran ST Birdsill AC Melah KE Okonkwo OC Alexander AL Dowling NM Johnson SC Sager MA Bendlin BB .
White matter microstructure in late middle-age: Effects of apolipoprotein E4 and parental family history of Alzheimer's disease. Neuroimage Clin. 2014;4:730-42
[PubMed ID: 24936424]
Racine AM Adluru N Alexander AL Christian BT Okonkwo OC Oh J Cleary CA Birdsill A Hillmer AT Murali D Barnhart TE Gallagher CL Carlsson CM Rowley HA Dowling NM Asthana S Sager MA Bendlin BB Johnson SC .
Associations between white matter microstructure and amyloid burden in preclinical Alzheimer's disease: A multimodal imaging investigation. Neuroimage Clin. 2014;4:604-14
[PubMed ID: 24936411]
Griffith HR Okonkwo OC Stewart CC Stoeckel LE Hollander JA Elgin JM Harrell LE Brockington JC Clark DG Ball KK Owsley C Marson DC Wadley VG .
Lower hippocampal volume predicts decrements in lane control among drivers with amnestic mild cognitive impairment. J Geriatr Psychiatry Neurol. 2013 Dec;26(4):259-66
[PubMed ID: 24212246]