Ozioma C. Okonkwo, PhD Print Friendly PageFaculty, University of Wisconsin School of Medicine and Public Health
Ozioma C. Okonkwo, PhD, is an Assistant Professor of Medicine at the University of Wisconsin School of Medicine and Public Health. He specializes in the neuropsychological evaluation of geriatric cognitive disorders, especially those due to suspected Alzheimer's disease.
UW Health Clinics
UW School of Medicine and Public Health
|Department of Medicine|
Professional Certifications and Education
Licensed Clinical Psychologist
NIH T32 AG027668, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD
VA Advanced Fellowship in Geriatrics, the Geriatric Research, Education, and Clinical Center (GRECC), William S. Middleton Memorial Veterans Hospital, Madison, WI
Warren Alpert Medical School of Brown University, Providence, RI
University of Alabama, Birmingham, AL, 2009
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Dr. Okonkwo's research focuses on clarifying how alterations in the brain and other biomolecules (such as cerebrospinal fluid β-amyloid) place some cognitively-normal individuals on a pernicious trajectory that culminates in probable Alzheimer's disease. In this context, Dr. Okonkwo is also interested in discovering new knowledge concerning the modulation of the link between brain changes and cognitive decline by both modifiable (e.g., cognitively stimulating activities, physical exercise) and non-modifiable (e.g., genetic vulnerability) factors.
Schultz SA Boots EA Darst BF Zetterberg H Blennow K Edwards DF Koscik RL Carlsson CM Gallagher CL Bendlin BB Asthana S Sager MA Hogan KJ Hermann BP Cook DB Johnson SC Engelman CD Okonkwo OC .
Cardiorespiratory fitness alters the influence of a polygenic risk score on biomarkers of AD. Neurology. 2017 Apr 25;88(17):1650-1658
[PubMed ID: 28341646]
Hoy AR Ly M Carlsson CM Okonkwo OC Zetterberg H Blennow K Sager MA Asthana S Johnson SC Alexander AL Bendlin BB .
Microstructural white matter alterations in preclinical Alzheimer's disease detected using free water elimination diffusion tensor imaging. PLoS One. 2017;12(3):e0173982
[PubMed ID: 28291839]
Dougherty RJ Schultz SA Boots EA Ellingson LD Meyer JD Van Riper S Stegner AJ Edwards DF Oh JM Einerson J Korcarz CE Koscik RL Dowling MN Gallagher CL Carlsson CM Rowley HA Bendlin BB Asthana S Hermann BP Sager MA Stein JH Johnson SC Okonkwo OC Cook DB .
Relationships between cardiorespiratory fitness, hippocampal volume, and episodic memory in a population at risk for Alzheimer's disease. Brain Behav. 2017 Mar;7(3):e00625
[PubMed ID: 28293467]
Oderinlo O Hassan AO Oluyadi FO Ogunro AO Okonkwo ON Ulaikere MO Ashano O .
Refractive aim and visual outcome after phacoemulsification: A 2-year review from a Tertiary Private Eye Hospital in Sub-Saharan Africa. Niger J Clin Pract. 2017 Feb;20(2):147-152
[PubMed ID: 28091428]
Okonkwo OC Vemuri P .
Stemming the Alzheimer tsunami: introduction to the special issue on reserve and resilience in Alzheimer's disease. Brain Imaging Behav. 2017 Jan 23;
[PubMed ID: 28116651]
Law LL Schultz SA Boots EA Einerson JA Dougherty RJ Oh JM Korcarz CE Edwards DF Koscik RL Dowling NM Gallagher CL Bendlin BB Carlsson CM Asthana S Hermann BP Sager MA Johnson SC Cook DB Stein JH Okonkwo OC .
Chronotropic Response and Cognitive Function in a Cohort at Risk for Alzheimer's Disease. J Alzheimers Dis. 2017;56(1):351-359
[PubMed ID: 27911299]
Darst BF Koscik RL Racine AM Oh JM Krause RA Carlsson CM Zetterberg H Blennow K Christian BT Bendlin BB Okonkwo OC Hogan KJ Hermann BP Sager MA Asthana S Johnson SC Engelman CD .
Pathway-Specific Polygenic Risk Scores as Predictors of Amyloid-β Deposition and Cognitive Function in a Sample at Increased Risk for Alzheimer's Disease. J Alzheimers Dis. 2017;55(2):473-484
[PubMed ID: 27662287]
Okonkwo OC Asthana S .
Dementia Trends in the United States: Read Up and Weigh In. JAMA Intern Med. 2017 Jan 1;177(1):58-60
[PubMed ID: 27893015]
Okonkwo OC Simons A Nichani J .
Paediatric airway foreign body - The human factors influencing patient safety in our hospitals. Int J Pediatr Otorhinolaryngol. 2016 Dec;91:100-104
[PubMed ID: 27863620]
Wang J Cunningham R Zetterberg H Asthana S Carlsson C Okonkwo O Li L .
Label-free quantitative comparison of cerebrospinal fluid glycoproteins and endogenous peptides in subjects with Alzheimer's disease, mild cognitive impairment, and healthy individuals. Proteomics Clin Appl. 2016 Dec;10(12):1225-1241
[PubMed ID: 27863112]
Koscik RL Berman SE Clark LR Mueller KD Okonkwo OC Gleason CE Hermann BP Sager MA Johnson SC .
Intraindividual Cognitive Variability in Middle Age Predicts Cognitive Impairment 8-10 Years Later: Results from the Wisconsin Registry for Alzheimer's Prevention. J Int Neuropsychol Soc. 2016 Nov;22(10):1016-1025
[PubMed ID: 27903330]
Dean DC 3rd Sojkova J Hurley S Kecskemeti S Okonkwo O Bendlin BB Theisen F Johnson SC Alexander AL Gallagher CL .
Alterations of Myelin Content in Parkinson's Disease: A Cross-Sectional Neuroimaging Study. PLoS One. 2016;11(10):e0163774
[PubMed ID: 27706215]
Yang R Sabharwal V Okonkwo OS Shlykova N Tong R Lin LY Wang W Guo S Rosowski JJ Pelton SI Kohane DS .
Treatment of otitis media by transtympanic delivery of antibiotics. Sci Transl Med. 2016 Sep 14;8(356):356ra120
[PubMed ID: 27629487]
Nzegwu MA Ohegbulam S Ndubuisi C Okwunodulu O Okorie E Nkwerem S Okonkwo O Aniume O Nnamani S Nwokoro O Eni A Nwideyi I Nzegwu V .
Cerebellar Liponeurocytoma: A Novel Report from Nigeria in a 6-Year-Old Girl, and Review of Literature. Rare Tumors. 2016 Sep 5;8(3):6240
[PubMed ID: 27746877]
Racine AM Koscik RL Berman SE Nicholas CR Clark LR Okonkwo OC Rowley HA Asthana S Bendlin BB Blennow K Zetterberg H Gleason CE Carlsson CM Johnson SC .
Biomarker clusters are differentially associated with longitudinal cognitive decline in late midlife. Brain. 2016 Aug;139(Pt 8):2261-74
[PubMed ID: 27324877]
Clark LR Racine AM Koscik RL Okonkwo OC Engelman CD Carlsson CM Asthana S Bendlin BB Chappell R Nicholas CR Rowley HA Oh JM Hermann BP Sager MA Christian BT Johnson SC .
Beta-amyloid and cognitive decline in late middle age: Findings from the Wisconsin Registry for Alzheimer's Prevention study. Alzheimers Dement. 2016 Jul;12(7):805-14
[PubMed ID: 26806386]
Merluzzi AP Dean DC 3rd Adluru N Suryawanshi GS Okonkwo OC Oh JM Hermann BP Sager MA Asthana S Zhang H Johnson SC Alexander AL Bendlin BB .
Age-dependent differences in brain tissue microstructure assessed with neurite orientation dispersion and density imaging. Neurobiol Aging. 2016 Jul;43:79-88
[PubMed ID: 27255817]
Okoye O Okonkwo O Oderinlo O Hassan K Ijasan A .
Bilateral concomitant intravitreal anti-vascular endothelial growth factor injection: Experience in a Nigerian tertiary private eye care facility. Niger J Clin Pract. 2016 Jul-Aug;19(4):544-8
[PubMed ID: 27251975]
Clark LR Koscik RL Nicholas CR Okonkwo OC Engelman CD Bratzke LC Hogan KJ Mueller KD Bendlin BB Carlsson CM Asthana S Sager MA Hermann BP Johnson SC .
Mild Cognitive Impairment in Late Middle Age in the Wisconsin Registry for Alzheimer's Prevention Study: Prevalence and Characteristics Using Robust and Standard Neuropsychological Normative Data. Arch Clin Neuropsychol. 2016 May 8;
[PubMed ID: 27193363]
Dougherty RJ Ellingson LD Schultz SA Boots EA Meyer JD Lindheimer JB Van Riper S Stegner AJ Edwards DF Oh JM Koscik RL Dowling MN Gallagher CL Carlsson CM Rowley HA Bendlin BB Asthana S Hermann BP Sager MA Johnson SC Okonkwo OC Cook DB .
Meeting physical activity recommendations may be protective against temporal lobe atrophy in older adults at risk for Alzheimer's disease. Alzheimers Dement (Amst). 2016;4:14-7
[PubMed ID: 27489874]