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John O. Fleming, MD

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John O. Fleming, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

John O. Fleming, MD, is a Professor of Neurology at the University of Wisconsin School of Medicine and Public Health. His medical interests include multiple sclerosis, viral infections of the central nervous system and hygiene hypothesis. Dr. Fleming’s teaching interests consist of multiple sclerosis, central nervous system infections and bioethics.



UW Health Clinics

University Hospital
(608) 262-0546 | (800) 323-8942 | Map

Hospital Affiliation(s)

University of Wisconsin Hospital and Clinics (primary)

UW School of Medicine and Public Health

Department of Neurology

Professional Certifications and Education

Board Certification Neurology
Internal Medicine
Fellowship University of Southern California
Residency Northshore University Hospital, Cornell University
Internship Kings County Hospital, Brooklyn, NY
Medical School State University of New York, Brooklyn, NY, 1971


UW Health Patient Experience Physician Champion Award 2015

Best Doctors® in America 2014

Best Doctors® in America 2013

Best Doctors® in America 2011

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.


Our doctors provide a wide range of services. The following list represents some, but not all, of the procedures offered by this physician.

  • Lumbar Puncture

Programs & Conditions


Dr. Fleming’s research currently consists of clinical trials of multiple sclerosis therapies, advanced neuroimaging in multiple sclerosis, animal models of viral-induced demyelination, immunochemistry of viruses and viral evolutions and persistence.

PubMed Articles
Fleming JO Carlsson CM . Biomarkers for neurology: Guides and lines. Neurology. 2014 Sep 23;83(13):1130-1
[PubMed ID: 25150288]
Hosseinbor AP Chung MK Wu YC Fleming JO Field AS Alexander AL . Extracting quantitative measures from EAP: a small clinical study using BFOR. Med Image Comput Comput Assist Interv. 2012;15(Pt 2):280-7
[PubMed ID: 23286059]
Fleming JO Cook TD . Multiple sclerosis and the hygiene hypothesis. Neurology. 2006 Dec 12;67(11):2085-6
[PubMed ID: 17159130]
Wu Y Alexander AL Fleming JO Duncan ID Field AS . Myelin water fraction in human cervical spinal cord in vivo. J Comput Assist Tomogr. 2006 Mar-Apr;30(2):304-6
[PubMed ID: 16628052]
Fee DB Fleming JO . Resolution of chronic inflammatory demyelinating polyneuropathy-associated central nervous system lesions after treatment with intravenous immunoglobulin. J Peripher Nerv Syst. 2003 Sep;8(3):155-8
[PubMed ID: 12904236]