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American Family Children's Hospital
James E. Gern, MD close
James E. Gern, MD

James E. Gern, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Gern is board-certified in Allergy and Immunology and Pediatrics. His areas of interest include childhood allergies, asthma, food allergies, and immune deficiency.


Pediatric Allergy, Asthma and Immunology

Pediatric Immunology

UW Health Clinics

West Clinic
(608) 263-6180 | (800) 323-8942 | Map
American Family Children's Hospital
(608) 263-6420 | (800) 323-8942 | Map

Hospital Affiliation(s)

University of Wisconsin Hospital and Clinics (primary)

Languages Spoken

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

UW School of Medicine and Public Health

Department of Medicine

Department of Pediatrics

Professional Certifications and Education

Board Certification Allergy & Immunology
Fellowship Johns Hopkins Hospital, Baltimore, MD
Residency State University of New York, Tufts University, Boston
Internship State University of New York, Syracuse, NY
Medical School University of Southern Florida, Tampa, 1981


Best Doctors® in America 2014

Best Doctors® in America 2013

Madison Magazine Top Docs 2012

Best Doctors® in America 2011


Our doctors provide a wide range of services. The following list represents some, but not all, of the procedures offered by this physician.

Programs & Conditions

  • Immunodeficiency Disorders

Dr. Gern leads several NIH-funded studies to define the role of viral infections in the initiation and disease activity of asthma, and to identify interactions between host and viral factors that determine the severity of respiratory illnesses. He is the Principal Investigator for the University of Wisconsin Asthma and Allergic Diseases Clinical Research Center.

PubMed Articles
Bochkov YA Grindle K Vang F Evans MD Gern JE . Improved molecular typing assay for rhinovirus species a, B, and C. J Clin Microbiol. 2014 Jul;52(7):2461-71
[PubMed ID: 24789198]
Wilson MR Naccache SN Samayoa E Biagtan M Bashir H Yu G Salamat SM Somasekar S Federman S Miller S Sokolic R Garabedian E Candotti F Buckley RH Reed KD Meyer TL Seroogy CM Galloway R Henderson SL Gern JE DeRisi JL Chiu CY . Actionable diagnosis of neuroleptospirosis by next-generation sequencing. N Engl J Med. 2014 Jun 19;370(25):2408-17
[PubMed ID: 24896819]
Bousquet J Gern JE Martinez FD Anto JM Johnson CC Holt PG Lemanske RF Jr Le Souëf PN Tepper RS von Mutius ER Arshad SH Bacharier LB Becker A Belanger K Bergström A Bernstein DI Cabana MD Carroll KN Castro M Cooper PJ Gillman MW Gold DR Henderson J Heinrich J Hong SJ Jackson DJ Keil T Kozyrskyj AL Lødrup Carlsen KC Miller RL Momas I Morgan WJ Noel P Ownby DR Pinart M Ryan PH Schwaninger JM Sears MR Simpson A Smit HA Stern DA Subbarao P Valenta R Wang X Weiss ST Wood R Wright AL Wright RJ Togias A Gergen PJ . Birth cohorts in asthma and allergic diseases: report of a NIAID/NHLBI/MeDALL joint workshop. J Allergy Clin Immunol. 2014 Jun;133(6):1535-46
[PubMed ID: 24636091]
Wickert LE Karta MR Audhya A Gern JE Bertics PJ . Simvastatin attenuates rhinovirus-induced interferon and CXCL10 secretion from monocytic cells in vitro. J Leukoc Biol. 2014 Jun;95(6):951-9
[PubMed ID: 24532643]
Lynch SV Wood RA Boushey H Bacharier LB Bloomberg GR Kattan M O'Connor GT Sandel MT Calatroni A Matsui E Johnson CC Lynn H Visness CM Jaffee KF Gergen PJ Gold DR Wright RJ Fujimura K Rauch M Busse WW Gern JE . Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children. J Allergy Clin Immunol. 2014 May 28;
[PubMed ID: 24908147]
Kloepfer KM Lee WM Pappas TE Kang TJ Vrtis RF Evans MD Gangnon RE Bochkov YA Jackson DJ Lemanske RF Jr Gern JE . Detection of pathogenic bacteria during rhinovirus infection is associated with increased respiratory symptoms and asthma exacerbations. J Allergy Clin Immunol. 2014 May;133(5):1301-7, 1307.e1-3
[PubMed ID: 24698319]
Karta MR Wickert LE Curran CS Gavala ML Denlinger LC Gern JE Bertics PJ . Allergen challenge in vivo alters rhinovirus-induced chemokine secretion from human airway macrophages. J Allergy Clin Immunol. 2014 Apr;133(4):1227-30
[PubMed ID: 24529411]
Obasi CN Barrett B Brown R Vrtis R Barlow S Muller D Gern J . Detection of viral and bacterial pathogens in acute respiratory infections. J Infect. 2014 Feb;68(2):125-30
[PubMed ID: 24211414]
Basta HA Ashraf S Sgro JY Bochkov YA Gern JE Palmenberg AC . Modeling of the human rhinovirus C capsid suggests possible causes for antiviral drug resistance. Virology. 2014 Jan 5;448:82-90
[PubMed ID: 24314639]
Brockman-Schneider RA Pickles RJ Gern JE . Effects of vitamin D on airway epithelial cell morphology and rhinovirus replication. PLoS One. 2014;9(1):e86755
[PubMed ID: 24475177]
Mathur SK Fichtinger PS Kelly JT Lee WM Gern JE Jarjour NN . Interaction between allergy and innate immunity: model for eosinophil regulation of epithelial cell interferon expression. Ann Allergy Asthma Immunol. 2013 Jul;111(1):25-31
[PubMed ID: 23806456]
Gavala ML Bashir H Gern JE . Virus/allergen interactions in asthma. Curr Allergy Asthma Rep. 2013 Jun;13(3):298-307
[PubMed ID: 23475539]
Ashraf S Brockman-Schneider R Bochkov YA Pasic TR Gern JE . Biological characteristics and propagation of human rhinovirus-C in differentiated sinus epithelial cells. Virology. 2013 Feb 5;436(1):143-9
[PubMed ID: 23199420]
Cadman RV Lemanske RF Jr Evans MD Jackson DJ Gern JE Sorkness RL Fain SB . Pulmonary 3He magnetic resonance imaging of childhood asthma. J Allergy Clin Immunol. 2013 Feb;131(2):369-76.e1-5
[PubMed ID: 23246019]
Singh AM Dahlberg P Burmeister K Evans MD Gangnon R Roberg KA Tisler C Dasilva D Pappas T Salazar L Lemanske RF Jr Gern JE Seroogy CM . Inhaled corticosteroid use is associated with increased circulating T regulatory cells in children with asthma. Clin Mol Allergy. 2013 Jan 25;11(1):1
[PubMed ID: 23347774]
Gern JE Pappas T Visness CM Jaffee KF Lemanske RF Togias A Bloomberg GR Cruikshank WW Lamm C Tuzova M Wood RA Lee WM . Comparison of the etiology of viral respiratory illnesses in inner-city and suburban infants. J Infect Dis. 2012 Nov;206(9):1342-9
[PubMed ID: 23014674]
Durrani SR Montville DJ Pratt AS Sahu S DeVries MK Rajamanickam V Gangnon RE Gill MA Gern JE Lemanske RF Jr Jackson DJ . Innate immune responses to rhinovirus are reduced by the high-affinity IgE receptor in allergic asthmatic children. J Allergy Clin Immunol. 2012 Aug;130(2):489-95
[PubMed ID: 22766097]
Manthei DM Jackson DJ Evans MD Gangnon RE Tisler CJ Gern JE Lemanske RF Jr Denlinger LC . Protection from asthma in a high-risk birth cohort by attenuated P2X(7) function. J Allergy Clin Immunol. 2012 Aug;130(2):496-502
[PubMed ID: 22743305]
Barrett B Hayney MS Muller D Rakel D Ward A Obasi CN Brown R Zhang Z Zgierska A Gern J West R Ewers T Barlow S Gassman M Coe CL . Meditation or exercise for preventing acute respiratory infection: a randomized controlled trial. Ann Fam Med. 2012 Jul-Aug;10(4):337-46
[PubMed ID: 22778122]
Kloepfer KM Olenec JP Lee WM Liu G Vrtis RF Roberg KA Evans MD Gangnon RE Lemanske RF Jr Gern JE . Increased H1N1 infection rate in children with asthma. Am J Respir Crit Care Med. 2012 Jun 15;185(12):1275-9
[PubMed ID: 22366048]