American Family Children's Hospital
James E. Gern, MD close
James E. Gern, MD

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James E. Gern, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Gern is board-certified in Allergy and Immunology and Pediatrics. His areas of interest include childhood allergies, asthma, food allergies, and immune deficiency.


Pediatric Allergy, Asthma and Immunology

UW Health Clinics

West Clinic
(608) 263-6180 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital (primary)

UW School of Medicine and Public Health

Department of Medicine

Department of Pediatrics

Professional Certifications and Education

Board Certification Allergy & Immunology
Fellowship The Johns Hopkins Hospital, Baltimore, MD
Internship State University of New York Upstate Medical University, Syracuse, NY
Medical School University of Southern Florida, Tampa, 1981


Madison Magazine Top Docs 2016

Madison Magazine Top Docs 2014

Best Doctors® in America 2014

Best Doctors® in America 2013

Madison Magazine Top Docs 2012

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.


Our doctors provide a wide range of services. The following list represents some, but not all, of the procedures offered by this physician.

Programs & Conditions

  • Allergic Rhinitis
  • Atopic Dermatitis/Eczema
  • Drug Allergies
  • Food Allergy
  • Immunodeficiency Disorders
  • Insect Sting Allergy
  • Latex Allergies
  • Preschool Wheezing
  • Recurrent Sinus Infection
  • Uticaria

Dr. Gern leads several NIH-funded studies to define the role of viral infections in the initiation and disease activity of asthma, and to identify interactions between host and viral factors that determine the severity of respiratory illnesses. He is the Principal Investigator for the University of Wisconsin Asthma and Allergic Diseases Clinical Research Center.

PubMed Articles
DeVries A Wlasiuk G Miller SJ Bosco A Stern DA Lohman IC Rothers J Jones AC Nicodemus-Johnson J Vasquez MM Curtin JA Simpson A Custovic A Jackson DJ Gern JE Lemanske RF Jr Guerra S Wright AL Ober C Halonen M Vercelli D . Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers. J Allergy Clin Immunol. 2017 Aug;140(2):534-542
[PubMed ID: 28011059]
Silkoff PE Flavin S Gordon R Loza MJ Sterk PJ Lutter R Diamant Z Turner RB Lipworth BJ Proud D Singh D Eich A Backer V Gern JE Herzmann C Halperin SA Mensinga TT Del Vecchio AM Branigan P San Mateo L Baribaud F Barnathan ES Johnston SL . TLR3 Blockade in Rhinovirus-Induced Experimental Asthma Exacerbations: A Randomized Controlled Study. J Allergy Clin Immunol. 2017 Jul 19;
[PubMed ID: 28734844]
Kloepfer KM Sarsani VK Poroyko V Lee WM Pappas TE Kang T Grindle KA Bochkov YA Janga SC Lemanske RF Jr Gern JE . Community-acquired rhinovirus infection is associated with changes in the airway microbiome. J Allergy Clin Immunol. 2017 Jul;140(1):312-315.e8
[PubMed ID: 28327377]
Koistinen A Lukkarinen M Turunen R Vuorinen T Vahlberg T Camargo CA Jr Gern J Ruuskanen O Jartti T . Prednisolone for the first rhinovirus-induced wheezing and 4-year asthma risk: A randomized trial. Pediatr Allergy Immunol. 2017 Jun 29;
[PubMed ID: 28660720]
Gern JE . Picornavectors. Am J Respir Crit Care Med. 2017 Jun 19;
[PubMed ID: 28628339]
Esquivel A Busse WW Calatroni A Togias AG Grindle KG Bochkov YA Gruchalla RS Kattan M Kercsmar CM Khurana Hershey G Kim H Lebeau P Liu AH Szefler SJ Teach SJ West JB Wildfire J Pongracic JA Gern JE . Effects of Omalizumab on Rhinovirus Infections, Illnesses and Exacerbations of Asthma. Am J Respir Crit Care Med. 2017 Jun 13;
[PubMed ID: 28608756]
Turunen R Vuorinen T Bochkov Y Gern J Jartti T . Clinical and Virus Surveillance After the First Wheezing Episode: Special Reference to Rhinovirus A and C Species. Pediatr Infect Dis J. 2017 Jun;36(6):539-544
[PubMed ID: 28027280]
Gold DR Adamkiewicz G Arshad SH Celedón JC Chapman MD Chew GL Cook DN Custovic A Gehring U Gern JE Johnson CC Kennedy S Koutrakis P Leaderer B Mitchell H Litonjua AA Mueller GA O'Connor GT Ownby D Phipatanakul W Persky V Perzanowski MS Ramsey CD Salo PM Schwaninger JM Sordillo JE Spira A Suglia SF Togias A Zeldin DC Matsui EC . NIAID, NIEHS, NHLBI, and MCAN Workshop Report: The indoor environment and childhood asthma-implications for home environmental intervention in asthma prevention and management. J Allergy Clin Immunol. 2017 May 10;
[PubMed ID: 28502823]
Griggs TF Bochkov YA Basnet S Pasic TR Brockman-Schneider RA Palmenberg AC Gern JE . Rhinovirus C targets ciliated airway epithelial cells. Respir Res. 2017 May 4;18(1):84
[PubMed ID: 28472984]
Annamalay AA Jroundi I Bizzintino J Khoo SK Zhang G Lehmann D Laing IA Gern J Goldblatt J Mahraoui C Benmessaoud R Moraleda C Bassat Q Le Souëf P . Rhinovirus C is associated with wheezing and rhinovirus A is associated with pneumonia in hospitalized children in Morocco. J Med Virol. 2017 Apr;89(4):582-588
[PubMed ID: 27677921]
Ramratnam SK Visness CM Jaffee KF Bloomberg GR Kattan M Sandel MT Wood RA Gern JE Wright RJ . Relationships among Maternal Stress and Depression, Type 2 Responses, and Recurrent Wheezing at Age 3 Years in Low-Income Urban Families. Am J Respir Crit Care Med. 2017 Mar 1;195(5):674-681
[PubMed ID: 27654103]
Anderson HM Lemanske RF Jr Arron JR Holweg CTJ Rajamanickam V Gangnon RE Gern JE Jackson DJ . Relationships among aeroallergen sensitization, peripheral blood eosinophils, and periostin in pediatric asthma development. J Allergy Clin Immunol. 2017 Mar;139(3):790-796
[PubMed ID: 27484037]
Jackson DJ Gern JE Lemanske RF Jr . Lessons learned from birth cohort studies conducted in diverse environments. J Allergy Clin Immunol. 2017 Feb;139(2):379-386
[PubMed ID: 28183432]
Anderson HM Lemanske RF Jr Evans MD Gangnon RE Pappas T Grindle K Bochkov YA Gern JE Jackson DJ . Assessment of wheezing frequency and viral etiology on childhood and adolescent asthma risk. J Allergy Clin Immunol. 2017 Feb;139(2):692-694
[PubMed ID: 27609657]
Rubner FJ Jackson DJ Evans MD Gangnon RE Tisler CJ Pappas TE Gern JE Lemanske RF Jr . Early life rhinovirus wheezing, allergic sensitization, and asthma risk at adolescence. J Allergy Clin Immunol. 2017 Feb;139(2):501-507
[PubMed ID: 27312820]
Gern JE Calatroni A Jaffee KF Lynn H Dresen A Cruikshank WW Lederman HM Sampson HA Shreffler W Bacharier LB Gergen PJ Gold DR Kattan M O'Connor GT Sandel MT Wood RA Bloomberg GR . Patterns of immune development in urban preschoolers with recurrent wheeze and/or atopy. J Allergy Clin Immunol. 2017 Jan 13;
[PubMed ID: 28089873]
Turunen R Jartti T Bochkov YA Gern JE Vuorinen T . Rhinovirus species and clinical characteristics in the first wheezing episode in children. J Med Virol. 2016 Dec;88(12):2059-2068
[PubMed ID: 27232888]
Bochkov YA Watters K Basnet S Sijapati S Hill M Palmenberg AC Gern JE . Mutations in VP1 and 3A proteins improve binding and replication of rhinovirus C15 in HeLa-E8 cells. Virology. 2016 Dec;499:350-360
[PubMed ID: 27743961]
Gern JE . Respiratory Syncytial Virus Bronchiolitis: Enter the Microbiome. Am J Respir Crit Care Med. 2016 Nov 1;194(9):1044-1045
[PubMed ID: 27797613]
Liu AH Babineau DC Krouse RZ Zoratti EM Pongracic JA O'Connor GT Wood RA Khurana Hershey GK Kercsmar CM Gruchalla RS Kattan M Teach SJ Makhija M Pillai D Lamm CI Gern JE Sigelman SM Gergen PJ Togias A Visness CM Busse WW . Pathways through which asthma risk factors contribute to asthma severity in inner-city children. J Allergy Clin Immunol. 2016 Oct;138(4):1042-1050
[PubMed ID: 27720018]