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Herbert Chen, MD close

Herbert Chen, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Chen earned his undergraduate degree from Stanford University and his medical degree from Duke University. He completed his residency in general surgery at Johns Hopkins Hospital, followed by a surgical oncology/endocrinology fellowship at Johns Hopkins Hospital and oncology center.


Dr. Chen is certified by the American Board of Surgery. He specializes in endocrine surgery, thyroid disease, hyperparathyroidism, adrenal tumors and neuroendocrine tumors. Dr. Chen is an expert in thyroid surgery (thyroidectomy, neck dissection), parathyroidectomy (minimally invasive radioguided parathyroidectomy – MIRP), adrenalectomy (laparoscopic), minimally invasive endocrine surgery and treatment of carcinoids.


Cancer Surgery

Surgery (General)

UW Health Clinics

UW Hospital and Clinics
(608) 263-7502 | (800) 323-8942 | Map
UW Hospital and Clinics
(608) 263-7502 | (800) 323-8942 | Map
UW Hospital and Clinics
(608) 263-7502 | (800) 323-8942 | Map
UW Carbone Cancer Center
(608) 263-7502 | (800) 323-8942 | Map
UW Hospital and Clinics
(608) 263-7502 | (800) 323-8942 | Map

Hospital Affiliation(s)

University of Wisconsin Hospital and Clinics (primary)
Veterans Hospital - Wm. S. Middleton Memorial (secondary)

UW School of Medicine and Public Health

General Surgery

Professional Certifications and Education

Board Certification Surgery

Postdoctoral Research Fellowship, The Johns Hopkins Oncology Center, Baltimore, MD, 1994-1997 Fellowship in Surgical Oncology, The Johns Hopkins Hospital, Baltimore, MD, 1998-2000

Residency Johns Hopkins Hospital, Baltimore, MD
Internship Johns Hopkins Hospital, Baltimore, MD
Medical School Duke University School of Medicine, Durham, NC


Best Doctors® in America 2014

Best Doctors® in America 2008-2013

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.


Our doctors provide a wide range of services. The following list represents some, but not all, of the procedures offered by this physician.


Dr. Chen conducts basic science research at the University of Wisconsin Carbone Cancer Center. His research program investigates the development, progression, and treatment of endocrine tumors including gastrointestinal carcinoids, thyroid cancer, and pancreatic islet cell tumors.

PubMed Articles
Ferguson LR Chen H Collins AR Connell M Damia G Dasgupta S Malhotra M Meeker AK Amedei A Amin A Ashraf SS Aquilano K Azmi AS Bhakta D Bilsland A Boosani CS Chen S Ciriolo MR Fujii H Guha G Halicka D Helferich WG Keith WN Mohammed SI Niccolai E Yang X Honoki K Parslow VR Prakash S Rezazadeh S Shackelford RE Sidransky D Tran PT Yang ES Maxwell CA . Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition. Semin Cancer Biol. 2015 Apr 10;
[PubMed ID: 25869442]
Elfenbein DM Schneider DF Havlena J Chen H Sippel RS . Clinical and socioeconomic factors influence treatment decisions in Graves' disease. Ann Surg Oncol. 2015 Apr;22(4):1196-9
[PubMed ID: 25245130]
Elfenbein DM Weber S Schneider DF Sippel RS Chen H . CaPTHUS scoring model in primary hyperparathyroidism: can it eliminate the need for ioPTH testing? Ann Surg Oncol. 2015 Apr;22(4):1191-5
[PubMed ID: 25212837]
Tevis SE Chen H . Surgery: Papillary thyroid cancer-how aggressive should surgery be? Nat Rev Endocrinol. 2015 Apr;11(4):195-6
[PubMed ID: 25687998]
Sohn JA Oltmann SC Schneider DF Sippel RS Chen H Elfenbein DM . Is intraoperative parathyroid hormone testing in patients with renal insufficiency undergoing parathyroidectomy for primary hyperparathyroidism accurate? Am J Surg. 2015 Mar;209(3):483-7
[PubMed ID: 25556028]
Rajaei MH Oltmann SC Schneider DF Sippel RS Chen H . Outcomes after subtotal parathyroidectomy for primary hyperparathyroidism due to hyperplasia: significance of whole vs. partial gland remnant. Ann Surg Oncol. 2015 Mar;22(3):966-71
[PubMed ID: 25245126]
Oltmann SC Brekke AV Schneider DF Schaefer SC Chen H Sippel RS . Preventing postoperative hypocalcemia in patients with Graves disease: a prospective study. Ann Surg Oncol. 2015 Mar;22(3):952-8
[PubMed ID: 25212835]
Somnay YR Weinlander E Alfhefdi A Schneider D Sippel RS Chen H . Radioguided parathyroidectomy for tertiary hyperparathyroidism. J Surg Res. 2015 Feb 19;
[PubMed ID: 25770735]
Liu S Jin K Hui Y Fu J Jie C Feng S Reisman D Wang Q Fan D Sukumar S Chen H . HOXB7 promotes malignant progression by activating the TGFβ signaling pathway. Cancer Res. 2015 Feb 15;75(4):709-19
[PubMed ID: 25542862]
Oltmann SC Schneider DF Chen H Sippel RS . All thyroid ultrasound evaluations are not equal: sonographers specialized in thyroid cancer correctly label clinical N0 disease in well differentiated thyroid cancer. Ann Surg Oncol. 2015 Feb;22(2):422-8
[PubMed ID: 25234019]
Rajaei MH Bentz AM Schneider DF Sippel RS Chen H Oltmann SC . Justified follow-up: a final intraoperative parathyroid hormone (ioPTH) Over 40 pg/mL is associated with an increased risk of persistence and recurrence in primary hyperparathyroidism. Ann Surg Oncol. 2015 Feb;22(2):454-9
[PubMed ID: 25192677]
Jaskula-Sztul R Eide J Tesfazghi S Dammalapati A Harrison AD Yu XM Scheinebeck C Winston-McPherson G Kupcho KR Robers MB Hundal AK Tang W Chen H . Tumor-suppressor role of Notch3 in medullary thyroid carcinoma revealed by genetic and pharmacological induction. Mol Cancer Ther. 2015 Feb;14(2):499-512
[PubMed ID: 25512616]
Zhou J Zhang M Huang Y Feng L Chen H Hu Y Chen H Zhang K Zheng L Zheng S . MicroRNA-320b promotes colorectal cancer proliferation and invasion by competing with its homologous microRNA-320a. Cancer Lett. 2015 Jan 28;356(2 Pt B):669-75
[PubMed ID: 25458952]
Schneider DF Elfenbein D Lloyd RV Chen H Sippel RS . Lymph node metastases do not impact survival in follicular variant papillary thyroid cancer. Ann Surg Oncol. 2015 Jan;22(1):158-63
[PubMed ID: 25092163]
Guille JT Opoku-Boateng A Thibeault SL Chen H . Evaluation and management of the pediatric thyroid nodule. Oncologist. 2015 Jan;20(1):19-27
[PubMed ID: 25480825]
Schneider DF Sonderman PE Jones MF Ojomo KA Chen H Jaume JC Elson DF Perlman SB Sippel RS . Failure of radioactive iodine in the treatment of hyperthyroidism. Ann Surg Oncol. 2014 Dec;21(13):4174-80
[PubMed ID: 25001092]
Patel PN Yu XM Jaskula-Sztul R Chen H . Hesperetin activates the Notch1 signaling cascade, causes apoptosis, and induces cellular differentiation in anaplastic thyroid cancer. Ann Surg Oncol. 2014 Dec;21 Suppl 4:S497-504
[PubMed ID: 24419754]
Wyche TP Dammalapati A Cho H Harrison AD Kwon GS Chen H Bugni TS Jaskula-Sztul R . Thiocoraline activates the Notch pathway in carcinoids and reduces tumor progression in vivo. Cancer Gene Ther. 2014 Dec;21(12):518-25
[PubMed ID: 25412645]
Hsu KT Sippel RS Chen H Schneider DF . Is central lymph node dissection necessary for parathyroid carcinoma? Surgery. 2014 Dec;156(6):1336-41; discussion 1341
[PubMed ID: 25456903]
Somnay YR Weinlander E Schneider DF Sippel RS Chen H . The effect of cinacalcet on intraoperative findings in tertiary hyperparathyroidism patients undergoing parathyroidectomy. Surgery. 2014 Dec;156(6):1308-13; discussion 1313-4
[PubMed ID: 25456900]