American Family Children's Hospital
Erik A. Ranheim, MD, PhD close
Erik A. Ranheim, MD, PhD

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Erik A. Ranheim, MD, PhD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Erik A. Ranheim, MD, PhD, earned his medical degree from the University of Minnesota and completed his residency at the Stanford University School of Medicine.



UW Health Clinics

University Hospital
(608) 263-8437 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital (primary)
Veterans Hospital - Wm. S. Middleton Memorial (secondary)

UW School of Medicine and Public Health

Department of Pathology and Laboratory Medicine

Professional Certifications and Education

Board Certification Hematopathology
Anatomic Pathology
Fellowship Stanford University School of Medicine
Residency Stanford University School of Medicine
Medical School University of Minnesota, 1996


Madison Magazine Top Docs 2016

Madison Magazine Top Docs 2014

Madison Magazine Top Docs 2012

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
PubMed Articles
Albertini MR Ranheim EA Zuleger CL Sondel PM Hank JA Bridges A Newton MA McFarland T Collins J Clements E Henry MB Neuman HB Weber S Whalen G Galili U . Phase I study to evaluate toxicity and feasibility of intratumoral injection of α-gal glycolipids in patients with advanced melanoma. Cancer Immunol Immunother. 2016 May 20;
[PubMed ID: 27207605]
Damnernsawad A Kong G Wen Z Liu Y Rajagopalan A You X Wang J Zhou Y Ranheim EA Luo HR Chang Q Zhang J . Kras is Required For Adult Hematopoiesis. Stem Cells. 2016 Mar 12;
[PubMed ID: 26972179]
Gao X Wu T Johnson KD Lahvic JL Ranheim EA Zon LI Bresnick EH . GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis. Stem Cell Reports. 2016 Mar 8;6(3):368-82
[PubMed ID: 26905203]
Gertz R Longley BJ Bennett D Ranheim E Rajamanickam V Kawahara T Endo J . Integrating virtual dermatopathology as part of formative and summative assessment of residents: a feasibility pilot study. J Cutan Pathol. 2015 Oct;42(10):779-81
[PubMed ID: 25990466]
Johnson KD Kong G Gao X Chang YI Hewitt KJ Sanalkumar R Prathibha R Ranheim EA Dewey CN Zhang J Bresnick EH . Cis-regulatory mechanisms governing stem and progenitor cell transitions. Sci Adv. 2015 Sep;1(8):e1500503
[PubMed ID: 26601269]
Zhang J Ranheim EA Du J Liu Y Wang J Kong G Zhang J . Deficiency of β Common Receptor Moderately Attenuates the Progression of Myeloproliferative Neoplasm in NrasG12D/+ Mice. J Biol Chem. 2015 Jul 31;290(31):19093-103
[PubMed ID: 26082490]
Swinnen LJ Li H Quon A Gascoyne R Hong F Ranheim EA Habermann TM Kahl BS Horning SJ Advani RH . Response-adapted therapy for aggressive non-Hodgkin's lymphomas based on early [18F] FDG-PET scanning: ECOG-ACRIN Cancer Research Group study (E3404). Br J Haematol. 2015 Jul;170(1):56-65
[PubMed ID: 25823885]
Chang YI Damnernsawad A Allen LK Yang D Ranheim EA Young KH Zhang J Kong G Wang J Liu Y Fu HY Yang CS Guo J Song H Zhang J . Evaluation of allelic strength of human TET2 mutations and cooperation between Tet2 knockdown and oncogenic Nras mutation. Br J Haematol. 2014 Aug;166(3):461-5
[PubMed ID: 24697267]
Ranheim EA . A novel program for clinical pathology training for residents emphasizing high-impact and attending-level learning opportunities. Hum Pathol. 2014 Feb;45(2):206-12
[PubMed ID: 24196188]
Yang RK Kalogriopoulos NA Rakhmilevich AL Ranheim EA Seo S Kim K Alderson KL Gan J Reisfeld RA Gillies SD Hank JA Sondel PM . Intratumoral treatment of smaller mouse neuroblastoma tumors with a recombinant protein consisting of IL-2 linked to the hu14.18 antibody increases intratumoral CD8+ T and NK cells and improves survival. Cancer Immunol Immunother. 2013 Aug;62(8):1303-13
[PubMed ID: 23661160]
Wang J Kong G Liu Y Du J Chang YI Tey SR Zhang X Ranheim EA Saba-El-Leil MK Meloche S Damnernsawad A Zhang J Zhang J . Nras(G12D/+) promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions. Blood. 2013 Jun 27;121(26):5203-7
[PubMed ID: 23687087]
Kong G Du J Liu Y Meline B Chang YI Ranheim EA Wang J Zhang J . Notch1 gene mutations target KRAS G12D-expressing CD8+ cells and contribute to their leukemogenic transformation. J Biol Chem. 2013 Jun 21;288(25):18219-27
[PubMed ID: 23673656]
Ranheim EA . Leukocyte abnormalities associated with hyperthermia. Int J Hematol. 2013 May;97(5):545-6
[PubMed ID: 23526098]
Yang RK Kalogriopoulos NA Rakhmilevich AL Ranheim EA Seo S Kim K Alderson KL Gan J Reisfeld RA Gillies SD Hank JA Sondel PM . Intratumoral hu14.18-IL-2 (IC) induces local and systemic antitumor effects that involve both activated T and NK cells as well as enhanced IC retention. J Immunol. 2012 Sep 1;189(5):2656-64
[PubMed ID: 22844125]
Buehler D Waknitz M Rehrauer W Ranheim E Selvaggi S . Small cell variant of malignant melanoma masquerading as lymphoma on fine-needle aspiration cytology: a case report. Diagn Cytopathol. 2012 Jul;40(7):619-23
[PubMed ID: 21472865]
Wang J Liu Y Tan LX Lo JC Du J Ryu MJ Ranheim EA Zhang J . Distinct requirements of hematopoietic stem cell activity and Nras G12D signaling in different cell types during leukemogenesis. Cell Cycle. 2011 Sep 1;10(17):2836-9
[PubMed ID: 21857161]
Wang J Liu Y Li Z Wang Z Tan LX Ryu MJ Meline B Du J Young KH Ranheim E Chang Q Zhang J . Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner. Blood. 2011 Jul 14;118(2):368-79
[PubMed ID: 21586752]
Visco C Hoeller S Malik JT Xu-Monette ZY Wiggins ML Liu J Sanger WG Liu Z Chang J Ranheim EA Gradowski JF Serrano S Wang HY Liu Q Dave S Olsen B Gascoyne RD Campo E Swerdlow SH Chan WC Tzankov A Young KH . Molecular characteristics of mantle cell lymphoma presenting with clonal plasma cell component. Am J Surg Pathol. 2011 Feb;35(2):177-89
[PubMed ID: 21263238]
Mathias JR Dodd ME Walters KB Yoo SK Ranheim EA Huttenlocher A . Characterization of zebrafish larval inflammatory macrophages. Dev Comp Immunol. 2009 Nov;33(11):1212-7
[PubMed ID: 19619578]
Wu QL Buhtoiarov IN Sondel PM Rakhmilevich AL Ranheim EA . Tumoricidal effects of activated macrophages in a mouse model of chronic lymphocytic leukemia. J Immunol. 2009 Jun 1;182(11):6771-8
[PubMed ID: 19454672]