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David R. Andes, MD
 


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David R. Andes, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Andes’ clinical interests include general infectious diseases, transplant infectious diseases, mycology, antimicrobial pharmacokinetics and pharmacodynamics. 

Specialties

Infectious Diseases

Travel Medicine

UW Health Clinics

University Hospital
(608) 263-0946 | (800) 323-8942 | Map
University Hospital
(608) 890-6167 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital (primary)
Veterans Hospital - Wm. S. Middleton Memorial, UnityPoint Health - Meriter (secondary)

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Infectious Diseases
Fellowship University of Wisconsin Hospital and Clinics, Madison, WI
Residency University of Wisconsin Hospital and Clinics, Madison, WI
Internship University of Wisconsin Hospital and Clinics, Madison, WI
Medical School University of Missouri School of Medicine, Columbia, MO, 1992

Awards/Honors

Best Doctors® in America 2015

Best Doctors® in America 2014

Best Doctors® in America 2013

Madison Magazine Top Docs 2012

 


Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
Research

The overriding themes of our research programs are to advance our understanding of antibacterial and antifungal activity and drug resistance, and to identify new antimicrobial drug treatment strategies and drug targets.


PubMed Articles
Lepak AJ Zhao M Berkow EL Lockhart SR Andes DR . Pharmacodynamic Optimization for Treatment of Invasive Candida auris Infection. Antimicrob Agents Chemother. 2017 Aug;61(8)
[PubMed ID: 28584152]
Srivastava A Sircaik S Husain F Thomas E Ror S Rastogi S Alim D Bapat P Andes DR Nobile CJ Panwar SL . Distinct roles of the 7-transmembrane receptor protein Rta3 in regulating the asymmetric distribution of phosphatidylcholine across the plasma membrane and biofilm formation in Candida albicans. Cell Microbiol. 2017 Jul 25;
[PubMed ID: 28745020]
Zhao M Lepak AJ Marchillo K VanHecker J Andes DR . In Vivo Pharmacodynamic Target Assessment of Eravacycline against Escherichia coli in a Murine Thigh Infection Model. Antimicrob Agents Chemother. 2017 Jul;61(7)
[PubMed ID: 28416552]
Lepak AJ Zhao M Andes DR . Comparative Pharmacodynamics of Telavancin and Vancomycin in the Neutropenic Murine Thigh and Lung Infection Models against Staphylococcus aureus. Antimicrob Agents Chemother. 2017 Jul;61(7)
[PubMed ID: 28416551]
Lepak AJ Zhao M VanScoy B Taylor DS Ellis-Grosse E Ambrose PG Andes DR . In Vivo Pharmacokinetics and Pharmacodynamics of ZTI-01 (Fosfomycin for Injection) in the Neutropenic Murine Thigh Infection Model against Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2017 Jun;61(6)
[PubMed ID: 28396549]
Alvarez C Andes DR Kang JY Krug C Kwon GS . Antifungal Efficacy of an Intravenous Formulation Containing Monomeric Amphotericin B, 5-Fluorocytosine, and Saline for Sodium Supplementation. Pharm Res. 2017 May;34(5):1115-1124
[PubMed ID: 28205003]
Lepak AJ Zhao M Marchillo K VanHecker J Andes DR . In Vivo Pharmacodynamic Evaluation of Omadacycline (PTK 0796) against Streptococcus pneumoniae in the Murine Pneumonia Model. Antimicrob Agents Chemother. 2017 May;61(5)
[PubMed ID: 28193651]
Bulik CC Okusanya ÓO Lakota EA Forrest A Bhavnani SM Hoover JL Andes DR Ambrose PG . Pharmacokinetic-Pharmacodynamic Evaluation of Gepotidacin against Gram-Positive Organisms Using Data from Murine Infection Models. Antimicrob Agents Chemother. 2017 Feb;61(2)
[PubMed ID: 27872075]
Zhao M Lepak AJ Andes DR . Animal models in the pharmacokinetic/pharmacodynamic evaluation of antimicrobial agents. Bioorg Med Chem. 2016 Dec 15;24(24):6390-6400
[PubMed ID: 27887963]
Woolford CA Lagree K Xu W Aleynikov T Adhikari H Sanchez H Cullen PJ Lanni F Andes DR Mitchell AP . Bypass of Candida albicans Filamentation/Biofilm Regulators through Diminished Expression of Protein Kinase Cak1. PLoS Genet. 2016 Dec;12(12):e1006487
[PubMed ID: 27935965]
Zarnowski R Sanchez H Andes DR . Large-scale production and isolation of Candida biofilm extracellular matrix. Nat Protoc. 2016 Dec;11(12):2320-2327
[PubMed ID: 27809313]
Andes DR Safdar N Baddley JW Alexander B Brumble L Freifeld A Hadley S Herwaldt L Kauffman C Lyon GM Morrison V Patterson T Perl T Walker R Hess T Chiller T Pappas PG . The epidemiology and outcomes of invasive Candida infections among organ transplant recipients in the United States: results of the Transplant-Associated Infection Surveillance Network (TRANSNET). Transpl Infect Dis. 2016 Dec;18(6):921-931
[PubMed ID: 27643395]
Kong EF Tsui C Kucharíková S Andes D Van Dijck P Jabra-Rizk MA . Commensal Protection of Staphylococcus aureus against Antimicrobials by Candida albicans Biofilm Matrix. MBio. 2016 Oct 11;7(5)
[PubMed ID: 27729510]
Shekhar-Guturja T Gunaherath GM Wijeratne EM Lambert JP Averette AF Lee SC Kim T Bahn YS Tripodi F Ammar R Döhl K Niewola-Staszkowska K Schmitt L Loewith RJ Roth FP Sanglard D Andes D Nislow C Coccetti P Gingras AC Heitman J Gunatilaka AA Cowen LE . Dual action antifungal small molecule modulates multidrug efflux and TOR signaling. Nat Chem Biol. 2016 Oct;12(10):867-75
[PubMed ID: 27571477]
Mitchell KF Zarnowski R Andes DR . Fungal Super Glue: The Biofilm Matrix and Its Composition, Assembly, and Functions. PLoS Pathog. 2016 Sep;12(9):e1005828
[PubMed ID: 27685086]
Winter MB Salcedo EC Lohse MB Hartooni N Gulati M Sanchez H Takagi J Hube B Andes DR Johnson AD Craik CS Nobile CJ . Global Identification of Biofilm-Specific Proteolysis in Candida albicans. MBio. 2016 Sep 13;7(5)
[PubMed ID: 27624133]
Dalal CK Zuleta IA Mitchell KF Andes DR El-Samad H Johnson AD . Transcriptional rewiring over evolutionary timescales changes quantitative and qualitative properties of gene expression. Elife. 2016 Sep 10;5
[PubMed ID: 27614020]
Lepak AJ Andes DR . In Vivo Pharmacodynamic Target Assessment of Delafloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumoniae in a Murine Lung Infection Model. Antimicrob Agents Chemother. 2016 Aug;60(8):4764-9
[PubMed ID: 27216072]
Pappas PG Kauffman CA Andes DR . Reply to Simon and to Eljaaly and Nix. Clin Infect Dis. 2016 Jul 15;63(2):287-8
[PubMed ID: 27114379]
Khandelwal NK Kaemmer P Förster TM Singh A Coste AT Andes DR Hube B Sanglard D Chauhan N Kaur R d'Enfert C Mondal AK Prasad R . Pleiotropic effects of the vacuolar ABC transporter MLT1 of Candida albicans on cell function and virulence. Biochem J. 2016 Jun 1;473(11):1537-52
[PubMed ID: 27026051]