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David R. Andes, MD close
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David R. Andes, MD
 

David R. Andes, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Andes’ clinical interests include general infectious diseases, transplant infectious diseases, mycology, antimicrobial pharmacokinetics and pharmacodynamics. 

Specialties

Infectious Diseases

Travel Medicine

UW Health Clinics

UW Hospital and Clinics
(608) 263-0946 | (800) 323-8942 | Map
UW Hospital and Clinics
(608) 890-6167 | (800) 323-8942 | Map

Hospital Affiliation(s)

University of Wisconsin Hospital and Clinics (primary)

Languages Spoken

English
Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Infectious Diseases
Internal Medicine
Fellowship University of Wisconsin Hospital and Clinics, Madison, WI
Residency University of Wisconsin Hospital and Clinics, Madison, WI
Internship University of Wisconsin Hospital and Clinics, Madison, WI
Medical School University of Missouri, 1992

Awards/Honors

Best Doctors® in America 2014

Best Doctors® in America 2013

Madison Magazine Top Docs 2012

Best Doctors® in America 2011


Research

The overriding themes of our research programs are to advance our understanding of antibacterial and antifungal activity and drug resistance, and to identify new antimicrobial drug treatment strategies and drug targets.


PubMed Articles
Sidoryk K Jaromin A Edward JA Switalska M Stefańska J Cmoch P Zagrodzka J Szczepek W Peczyńska-Czoch W Wietrzyk J Kozubek A Zarnowski R Andes DR Kaczmarek L . Searching for new derivatives of neocryptolepine: Synthesis, antiproliferative, antimicrobial and antifungal activities. Eur J Med Chem. 2014 May 6;78:304-13
[PubMed ID: 24686017]
Ng JK Schulz LT Rose WE Fox BC Andes DR Buhr KA Fish JT . Daptomycin dosing based on ideal body weight versus actual body weight: comparison of clinical outcomes. Antimicrob Agents Chemother. 2014 Jan;58(1):88-93
[PubMed ID: 24145531]
Lepak AJ Marchillo K Vanhecker J Andes DR . Isavuconazole (BAL4815) pharmacodynamic target determination in an in vivo murine model of invasive pulmonary aspergillosis against wild-type and cyp51 mutant isolates of Aspergillus fumigatus. Antimicrob Agents Chemother. 2013 Dec;57(12):6284-9
[PubMed ID: 24100500]
Andes D Casadevall A . Insights into fungal pathogenesis from the iatrogenic epidemic of Exserohilum rostratum fungal meningitis. Fungal Genet Biol. 2013 Dec;61:143-5
[PubMed ID: 24012946]
Lepak AJ Marchillo K VanHecker J Diekema D Andes DR . Isavuconazole pharmacodynamic target determination for Candida species in an in vivo murine disseminated candidiasis model. Antimicrob Agents Chemother. 2013 Nov;57(11):5642-8
[PubMed ID: 24002092]
Lepak AJ Marchillo K VanHecker J Andes DR . Impact of in vivo triazole and echinocandin combination therapy for invasive pulmonary aspergillosis: enhanced efficacy against Cyp51 mutant isolates. Antimicrob Agents Chemother. 2013 Nov;57(11):5438-47
[PubMed ID: 23959322]
Andes DR Reynolds DK Van Wart SA Lepak AJ Kovanda LL Bhavnani SM . Clinical pharmacodynamic index identification for micafungin in esophageal candidiasis: dosing strategy optimization. Antimicrob Agents Chemother. 2013 Nov;57(11):5714-6
[PubMed ID: 23959319]
Taff HT Mitchell KF Edward JA Andes DR . Mechanisms of Candida biofilm drug resistance. Future Microbiol. 2013 Oct;8(10):1325-37
[PubMed ID: 24059922]
Andes D . Optimizing antifungal choice and administration. Curr Med Res Opin. 2013 Apr;29 Suppl 4:13-8
[PubMed ID: 23621589]
Tebbets B Yu Z Stewart D Zhao LX Jiang Y Xu LH Andes D Shen B Klein B . Identification of antifungal natural products via Saccharomyces cerevisiae bioassay: insights into macrotetrolide drug spectrum, potency and mode of action. Med Mycol. 2013 Apr;51(3):280-9
[PubMed ID: 22928922]
Lee DG Murakami Y Andes DR Craig WA . Inoculum effects of ceftobiprole, daptomycin, linezolid, and vancomycin with Staphylococcus aureus and Streptococcus pneumoniae at inocula of 10(5) and 10(7) CFU injected into opposite thighs of neutropenic mice. Antimicrob Agents Chemother. 2013 Mar;57(3):1434-41
[PubMed ID: 23295932]
Palmer JM Bok JW Lee S Dagenais TR Andes DR Kontoyiannis DP Keller NP . Loss of CclA, required for histone 3 lysine 4 methylation, decreases growth but increases secondary metabolite production in Aspergillus fumigatus. PeerJ. 2013;1:e4
[PubMed ID: 23638376]
Lepak AJ Marchillo K Vanhecker J Andes DR . Posaconazole pharmacodynamic target determination against wild-type and Cyp51 mutant isolates of Aspergillus fumigatus in an in vivo model of invasive pulmonary aspergillosis. Antimicrob Agents Chemother. 2013 Jan;57(1):579-85
[PubMed ID: 23147740]
Lepak AJ Marchillo K Pichereau S Craig WA Andes DR . Comparative pharmacodynamics of the new oxazolidinone tedizolid phosphate and linezolid in a neutropenic murine Staphylococcus aureus pneumonia model. Antimicrob Agents Chemother. 2012 Nov;56(11):5916-22
[PubMed ID: 22964254]
Lepak A Castanheira M Diekema D Pfaller M Andes D . Optimizing Echinocandin dosing and susceptibility breakpoint determination via in vivo pharmacodynamic evaluation against Candida glabrata with and without fks mutations. Antimicrob Agents Chemother. 2012 Nov;56(11):5875-82
[PubMed ID: 22948870]
Peltier-Pain P Marchillo K Zhou M Andes DR Thorson JS . Natural product disaccharide engineering through tandem glycosyltransferase catalysis reversibility and neoglycosylation. Org Lett. 2012 Oct 5;14(19):5086-9
[PubMed ID: 22984807]
Rose WE Schulz LT Andes D Striker R Berti AD Hutson PR Shukla SK . Addition of ceftaroline to daptomycin after emergence of daptomycin-nonsusceptible Staphylococcus aureus during therapy improves antibacterial activity. Antimicrob Agents Chemother. 2012 Oct;56(10):5296-302
[PubMed ID: 22869564]
Andes DR Safdar N Baddley JW Playford G Reboli AC Rex JH Sobel JD Pappas PG Kullberg BJ . Impact of treatment strategy on outcomes in patients with candidemia and other forms of invasive candidiasis: a patient-level quantitative review of randomized trials. Clin Infect Dis. 2012 Apr;54(8):1110-22
[PubMed ID: 22412055]
Nett JE Marchillo K Andes DR . Modeling of fungal biofilms using a rat central vein catheter. Methods Mol Biol. 2012;845:547-56
[PubMed ID: 22328403]
Tebbets B Stewart D Lawry S Nett J Nantel A Andes D Klein BS . Identification and characterization of antifungal compounds using a Saccharomyces cerevisiae reporter bioassay. PLoS One. 2012;7(5):e36021
[PubMed ID: 22574132]