David M. Gamm, MD, PhD Print Friendly PageFaculty, University of Wisconsin School of Medicine and Public Health
David Gamm, PhD, MD, is both a clinician and a researcher. His clinical practice is in pediatric ophthalmology and his research interests focus on human retinal development and disease.
Dr. Gamm earned his medical degree from the University of Michigan in Ann Arbor and completed his residency at UW Hospital and Clinics.
UW Health Clinics
Professional Certifications and Education
University of Wisconsin Hospital and Clinics, Madison, WI
University of Wisconsin Hospital and Clinics, Madison, WI
Spectrum Hospital, Grand Rapids, MI
University of Michigan Medical School, Ann Arbor, MI, 1998
|Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.|
Our doctors provide a wide range of services. The following list represents some, but not all, of the procedures offered by this physician.
Programs & Conditions
Capowski EE Wright LS Liang K Phillips MJ Wallace K Petelinsek A Hagstrom A Pinilla I Borys K Lien J Min JH Keles S Thomson JA Gamm DM .
Regulation of WNT Signaling by VSX2 During Optic Vesicle Patterning in Human Induced Pluripotent Stem Cells. Stem Cells. 2016 Jun 14;
[PubMed ID: 27301076]
Leach LL Croze RH Hu Q Nadar VP Clevenger TN Pennington BO Gamm DM Clegg DO .
Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods. J Ocul Pharmacol Ther. 2016 Jun;32(5):317-30
[PubMed ID: 27182743]
Singh R Kuai D Guziewicz KE Meyer J Wilson M Lu J Smith M Clark E Verhoeven A Aguirre GD Gamm DM .
Pharmacological Modulation of Photoreceptor Outer Segment Degradation in a Human iPS Cell Model of Inherited Macular Degeneration. Mol Ther. 2015 Nov;23(11):1700-11
[PubMed ID: 26300224]
Gamm DM Wong R .
Report on the National Eye Institute Audacious Goals Initiative: Photoreceptor Regeneration and Integration Workshop. Transl Vis Sci Technol. 2015 Nov;4(6):2
[PubMed ID: 26629398]
Kushner BJ Gamm DM .
Eye muscle surgery for recurrent nystagmus related to head tilt after prior torsional surgery. J AAPOS. 2015 Jun;19(3):211-6
[PubMed ID: 26059663]
Thompson DA Ali RR Banin E Branham KE Flannery JG Gamm DM Hauswirth WW Heckenlively JR Iannaccone A Jayasundera KT Khan NW Molday RS Pennesi ME Reh TA Weleber RG Zacks DN .
Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium. Invest Ophthalmol Vis Sci. 2015 Feb 9;56(2):918-31
[PubMed ID: 25667399]
Wright LS Pinilla I Saha J Clermont JM Lien JS Borys KD Capowski EE Phillips MJ Gamm DM .
VSX2 and ASCL1 Are Indicators of Neurogenic Competence in Human Retinal Progenitor Cultures. PLoS One. 2015;10(8):e0135830
[PubMed ID: 26292211]
Capowski EE Simonett JM Clark EM Wright LS Howden SE Wallace KA Petelinsek AM Pinilla I Phillips MJ Meyer JS Schneider BL Thomson JA Gamm DM .
Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation. Hum Mol Genet. 2014 Dec 1;23(23):6332-44
[PubMed ID: 25008112]
Zhong X Gutierrez C Xue T Hampton C Vergara MN Cao LH Peters A Park TS Zambidis ET Meyer JS Gamm DM Yau KW Canto-Soler MV .
Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs. Nat Commun. 2014 Jun 10;5:4047
[PubMed ID: 24915161]
Wright LS Phillips MJ Pinilla I Hei D Gamm DM .
Induced pluripotent stem cells as custom therapeutics for retinal repair: progress and rationale. Exp Eye Res. 2014 Jun;123:161-72
[PubMed ID: 24534198]
Phillips MJ Perez ET Martin JM Reshel ST Wallace KA Capowski EE Singh R Wright LS Clark EM Barney PM Stewart R Dickerson SJ Miller MJ Percin EF Thomson JA Gamm DM .
Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2. Stem Cells. 2014 Jun;32(6):1480-92
[PubMed ID: 24532057]
Singh R Phillips MJ Kuai D Meyer J Martin JM Smith MA Perez ET Shen W Wallace KA Capowski EE Wright LS Gamm DM .
Functional analysis of serially expanded human iPS cell-derived RPE cultures. Invest Ophthalmol Vis Sci. 2013 Oct 17;54(10):6767-78
[PubMed ID: 24030465]
Gamm DM Wright LS .
From embryonic stem cells to mature photoreceptors. Nat Biotechnol. 2013 Aug;31(8):712-3
[PubMed ID: 23929346]
Gamm DM Phillips MJ Singh R .
Modeling retinal degenerative diseases with human iPS-derived cells: current status and future implications. Expert Rev Ophthalmol. 2013 Jun 1;8(3):213-216
[PubMed ID: 24039627]
Singh R Shen W Kuai D Martin JM Guo X Smith MA Perez ET Phillips MJ Simonett JM Wallace KA Verhoeven AD Capowski EE Zhang X Yin Y Halbach PJ Fishman GA Wright LS Pattnaik BR Gamm DM .
iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration. Hum Mol Genet. 2013 Feb 1;22(3):593-607
[PubMed ID: 23139242]
Phillips MJ Wallace KA Dickerson SJ Miller MJ Verhoeven AD Martin JM Wright LS Shen W Capowski EE Percin EF Perez ET Zhong X Canto-Soler MV Gamm DM .
Blood-derived human iPS cells generate optic vesicle-like structures with the capacity to form retinal laminae and develop synapses. Invest Ophthalmol Vis Sci. 2012 Apr 18;53(4):2007-19
[PubMed ID: 22410558]
Meyer JS Howden SE Wallace KA Verhoeven AD Wright LS Capowski EE Pinilla I Martin JM Tian S Stewart R Pattnaik B Thomson JA Gamm DM .
Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment. Stem Cells. 2011 Aug;29(8):1206-18
[PubMed ID: 21678528]
Howden SE Gore A Li Z Fung HL Nisler BS Nie J Chen G McIntosh BE Gulbranson DR Diol NR Taapken SM Vereide DT Montgomery KD Zhang K Gamm DM Thomson JA .
Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6537-42
[PubMed ID: 21464322]
Meyer JS Shearer RL Capowski EE Wright LS Wallace KA McMillan EL Zhang SC Gamm DM .
Modeling early retinal development with human embryonic and induced pluripotent stem cells. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16698-703
[PubMed ID: 19706890]
Gamm DM Wright LS Capowski EE Shearer RL Meyer JS Kim HJ Schneider BL Melvan JN Svendsen CN .
Regulation of prenatal human retinal neurosphere growth and cell fate potential by retinal pigment epithelium and Mash1. Stem Cells. 2008 Dec;26(12):3182-93
[PubMed ID: 18802035]