David M. Gamm, MD, PhD Print Friendly PageFaculty, University of Wisconsin School of Medicine and Public Health
David Gamm, PhD, MD, is both a clinician and a researcher. His clinical practice is in pediatric ophthalmology and his research interests focus on human retinal development and disease.
Dr. Gamm earned his medical degree from the University of Michigan in Ann Arbor and completed his residency at UW Hospital and Clinics.
UW Health Clinics
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Professional Certifications and Education
University of Wisconsin Hospital and Clinics, Madison, WI
University of Wisconsin Hospital and Clinics, Madison, WI
Spectrum Hospital, Grand Rapids, MI
University of Michigan Medical School, Ann Arbor, MI, 1998
Our doctors provide a wide range of services. The following list represents some, but not all, of the procedures offered by this physician.
Programs & Conditions
Capowski EE Simonett JM Clark EM Wright LS Howden SE Wallace KA Petelinsek AM Pinilla I Phillips MJ Meyer JS Schneider BL Thomson JA Gamm DM .
Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation. Hum Mol Genet. 2014 Jul 9;
[PubMed ID: 25008112]
Zhong X Gutierrez C Xue T Hampton C Vergara MN Cao LH Peters A Park TS Zambidis ET Meyer JS Gamm DM Yau KW Canto-Soler MV .
Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs. Nat Commun. 2014 Jun 10;5:4047
[PubMed ID: 24915161]
Wright LS Phillips MJ Pinilla I Hei D Gamm DM .
Induced pluripotent stem cells as custom therapeutics for retinal repair: progress and rationale. Exp Eye Res. 2014 Jun;123:161-72
[PubMed ID: 24534198]
Phillips MJ Perez ET Martin JM Reshel ST Wallace KA Capowski EE Singh R Wright LS Clark EM Barney PM Stewart R Dickerson SJ Miller MJ Percin EF Thomson JA Gamm DM .
Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2. Stem Cells. 2014 Jun;32(6):1480-92
[PubMed ID: 24532057]
Singh R Phillips MJ Kuai D Meyer J Martin JM Smith MA Perez ET Shen W Wallace KA Capowski EE Wright LS Gamm DM .
Functional analysis of serially expanded human iPS cell-derived RPE cultures. Invest Ophthalmol Vis Sci. 2013 Oct 17;54(10):6767-78
[PubMed ID: 24030465]
Gamm DM Wright LS .
From embryonic stem cells to mature photoreceptors. Nat Biotechnol. 2013 Aug;31(8):712-3
[PubMed ID: 23929346]
Gamm DM Phillips MJ Singh R .
Modeling retinal degenerative diseases with human iPS-derived cells: current status and future implications. Expert Rev Ophthalmol. 2013 Jun 1;8(3):213-216
[PubMed ID: 24039627]
Singh R Shen W Kuai D Martin JM Guo X Smith MA Perez ET Phillips MJ Simonett JM Wallace KA Verhoeven AD Capowski EE Zhang X Yin Y Halbach PJ Fishman GA Wright LS Pattnaik BR Gamm DM .
iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration. Hum Mol Genet. 2013 Feb 1;22(3):593-607
[PubMed ID: 23139242]
Phillips MJ Wallace KA Dickerson SJ Miller MJ Verhoeven AD Martin JM Wright LS Shen W Capowski EE Percin EF Perez ET Zhong X Canto-Soler MV Gamm DM .
Blood-derived human iPS cells generate optic vesicle-like structures with the capacity to form retinal laminae and develop synapses. Invest Ophthalmol Vis Sci. 2012 Apr 18;53(4):2007-19
[PubMed ID: 22410558]
Meyer JS Howden SE Wallace KA Verhoeven AD Wright LS Capowski EE Pinilla I Martin JM Tian S Stewart R Pattnaik B Thomson JA Gamm DM .
Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment. Stem Cells. 2011 Aug;29(8):1206-18
[PubMed ID: 21678528]
Howden SE Gore A Li Z Fung HL Nisler BS Nie J Chen G McIntosh BE Gulbranson DR Diol NR Taapken SM Vereide DT Montgomery KD Zhang K Gamm DM Thomson JA .
Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6537-42
[PubMed ID: 21464322]
Meyer JS Shearer RL Capowski EE Wright LS Wallace KA McMillan EL Zhang SC Gamm DM .
Modeling early retinal development with human embryonic and induced pluripotent stem cells. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16698-703
[PubMed ID: 19706890]
Gamm DM Wright LS Capowski EE Shearer RL Meyer JS Kim HJ Schneider BL Melvan JN Svendsen CN .
Regulation of prenatal human retinal neurosphere growth and cell fate potential by retinal pigment epithelium and Mash1. Stem Cells. 2008 Dec;26(12):3182-93
[PubMed ID: 18802035]
Gamm DM Melvan JN Shearer RL Pinilla I Sabat G Svendsen CN Wright LS .
A novel serum-free method for culturing human prenatal retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2008 Feb;49(2):788-99
[PubMed ID: 18235029]
Gamm DM Wang S Lu B Girman S Holmes T Bischoff N Shearer RL Sauvé Y Capowski E Svendsen CN Lund RD .
Protection of visual functions by human neural progenitors in a rat model of retinal disease. PLoS One. 2007 Mar 28;2(3):e338
[PubMed ID: 17396165]
Griepentrog GJ Aagaard-Kienitz B Kushner BJ Iskandar BJ Gamm DM .
Unilateral eyelid swelling and ptosis caused by dural arteriovenous fistula in an infant. Arch Ophthalmol. 2006 Sep;124(9):1359-61
[PubMed ID: 16966640]
Gamm DM Harris A Mehran RJ Wood M Foster CS Mootha VV .
Mucous membrane pemphigoid with fatal bronchial involvement in a seventeen-year-old girl. Cornea. 2006 May;25(4):474-8
[PubMed ID: 16670490]
Gamm DM Nelson AD Svendsen CN .
Human retinal progenitor cells grown as neurospheres demonstrate time-dependent changes in neuronal and glial cell fate potential. Ann N Y Acad Sci. 2005 May;1049:107-17
[PubMed ID: 15965111]
Albert DM Nickells RW Gamm DM Zimbric ML Schlamp CL Lindstrom MJ Audo I .
Vitamin D analogs, a new treatment for retinoblastoma: The first Ellsworth Lecture. Ophthalmic Genet. 2002 Sep;23(3):137-56
[PubMed ID: 12324873]