American Family Children's Hospital
Daniel Muller, MD, PhD close
Daniel Muller, MD, PhD

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Daniel Muller, MD, PhD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Daniel Muller, MD, PhD, joined the University of Wisconsin faculty in 1991. He graduated from Nassau Community College in 1973 with an AA degree in liberal arts and from the State University of New York at Binghamton in 1975 with a BS in biological sciences. He then did graduate work at the UW in the Department of Medical Microbiology, obtaining a MS degree in 1979 and a PhD in 1981. Dr. Muller studied medicine at the State University of New York at Stony Brook, obtaining the MD degree in 1985, and he was elected to the Alpha Omega Alpha honor society. He spent 6 years at the University of North Carolina at Chapel Hill training in internal medicine, rheumatology and basic science immunogenetics. 

Dr. Muller lectures on the basic science of autoimmune disease and the aging of the immune system. He is the course director for the UW School of Medicine and Public Health elective in complementary and alternative medicine.


Rheumatology and Arthritis

UW Health Clinics

1 S. Park Clinic
(608) 287-2800 | (888) 703-2778 | Map

Hospital Affiliation(s)

UnityPoint Health - Meriter (primary)

UW School of Medicine and Public Health

Department of Medicine


Professional Certifications and Education

Board Certification Internal Medicine
Fellowship University of North Carolina Hospitals, Chapel Hill, NC
Residency North Carolina Memorial Hospital, Chapel Hill, NC
Internship North Carolina Memorial Hospital, Chapel Hill, NC
Medical School State University of New York, Stony Brook, NY, 1985

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.


Our doctors provide a wide range of services. The following list represents some, but not all, of the procedures offered by this physician.

Programs & Conditions

  • Auto Immune Disorders
  • Lupus

Dr. Muller has been funded by the National Institutes of Health (NIH) and by the World Health Organization (WHO) in his prior work on the genetics of the immune response to chronic viral and bacterial infections and protection by vaccination. Dr. Muller is currently interested in the field of psychoneuroendocrineimmunology, also known as mind-body medicine. He has a particular interest and is currently funded by the NIH to study the influence of meditation on disease and health.


Dr. Muller and his colleagues are investigating what factors influence the overall mental and physical health of an individual. They are participating in studies shared by a multidisciplinary group of scientists examining the roles of social, demographic, psychological, neurophysiological, immune, and biomedical factors on health and disease. The group is focusing on persons identified as "resilient" compared to persons identified as "vulnerable," and what factors interact to yield a happy and healthy individual. The laboratory examines the effects of these factors on the function of the immune system.

PubMed Articles
Obasi CN Barrett B Brown R Vrtis R Barlow S Muller D Gern J . Detection of viral and bacterial pathogens in acute respiratory infections. J Infect. 2014 Feb;68(2):125-30
[PubMed ID: 24211414]
Hayney MS Coe CL Muller D Obasi CN Backonja U Ewers T Barrett B . Age and psychological influences on immune responses to trivalent inactivated influenza vaccine in the meditation or exercise for preventing acute respiratory infection (MEPARI) trial. Hum Vaccin Immunother. 2014;10(1):83-91
[PubMed ID: 24096366]
Zgierska A Obasi CN Brown R Ewers T Muller D Gassman M Barlow S Barrett B . Randomized controlled trial of mindfulness meditation and exercise for the prevention of acute respiratory infection: possible mechanisms of action. Evid Based Complement Alternat Med. 2013;2013:952716
[PubMed ID: 24191174]
Barrett B Hayney MS Muller D Rakel D Ward A Obasi CN Brown R Zhang Z Zgierska A Gern J West R Ewers T Barlow S Gassman M Coe CL . Meditation or exercise for preventing acute respiratory infection: a randomized controlled trial. Ann Fam Med. 2012 Jul-Aug;10(4):337-46
[PubMed ID: 22778122]
Loevinger BL Shirtcliff EA Muller D Alonso C Coe CL . Delineating psychological and biomedical profiles in a heterogeneous fibromyalgia population using cluster analysis. Clin Rheumatol. 2012 Apr;31(4):677-85
[PubMed ID: 22200814]
Backonja MM Coe CL Muller DA Schell K . Altered cytokine levels in the blood and cerebrospinal fluid of chronic pain patients. J Neuroimmunol. 2008 Mar;195(1-2):157-63
[PubMed ID: 18325600]
Dopp JM Wiegert NA Moran JJ Muller D Weber S Hayney MS . Humoral immune responses to influenza vaccination in patients with obstructive sleep apnea. Pharmacotherapy. 2007 Nov;27(11):1483-9
[PubMed ID: 17963457]
Loevinger BL Muller D Alonso C Coe CL . Metabolic syndrome in women with chronic pain. Metabolism. 2007 Jan;56(1):87-93
[PubMed ID: 17161230]
Barrett B Muller D Rakel D Rabago D Marchand L Scheder JC . Placebo, meaning, and health. Perspect Biol Med. 2006 Spring;49(2):178-98
[PubMed ID: 16702703]
Ryff CD Dienberg Love G Urry HL Muller D Rosenkranz MA Friedman EM Davidson RJ Singer B . Psychological well-being and ill-being: do they have distinct or mirrored biological correlates? Psychother Psychosom. 2006;75(2):85-95
[PubMed ID: 16508343]
Rindfleisch JA Muller D . Diagnosis and management of rheumatoid arthritis. Am Fam Physician. 2005 Sep 15;72(6):1037-47
[PubMed ID: 16190501]
Schleicher H Alonso C Shirtcliff EA Muller D Loevinger BL Coe CL . In the face of pain: the relationship between psychological well-being and disability in women with fibromyalgia. Psychother Psychosom. 2005;74(4):231-9
[PubMed ID: 15947513]
Alonso C Loevinger BL Muller D Coe CL . Menstrual cycle influences on pain and emotion in women with fibromyalgia. J Psychosom Res. 2004 Nov;57(5):451-8
[PubMed ID: 15581648]
Hayney MS Muller D . Effect of influenza immunization on CYP3A4 activity in vivo. J Clin Pharmacol. 2003 Dec;43(12):1377-81
[PubMed ID: 14615474]
Rosenkranz MA Jackson DC Dalton KM Dolski I Ryff CD Singer BH Muller D Kalin NH Davidson RJ . Affective style and in vivo immune response: neurobehavioral mechanisms. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):11148-52
[PubMed ID: 12960387]
Davidson RJ Kabat-Zinn J Schumacher J Rosenkranz M Muller D Santorelli SF Urbanowski F Harrington A Bonus K Sheridan JF . Alterations in brain and immune function produced by mindfulness meditation. Psychosom Med. 2003 Jul-Aug;65(4):564-70
[PubMed ID: 12883106]
Hayney MS Love GD Buck JM Ryff CD Singer B Muller D . The association between psychosocial factors and vaccine-induced cytokine production. Vaccine. 2003 Jun 2;21(19-20):2428-32
[PubMed ID: 12744875]
Hayney MS Love GD Carlberg BM Buck JM Muller D . Tetanus seroprevalence among farmers: a preliminary study. J Rural Health. 2003 Spring;19(2):109-12
[PubMed ID: 12696846]
Hayney MS Buck JM Muller D . Production of interferon-gamma and interleukin-10 after inactivated hepatitis A immunization. Pharmacotherapy. 2003 Apr;23(4):431-5
[PubMed ID: 12680472]