American Family Children's Hospital
Christine M. Seroogy, MD close
Christine M. Seroogy, MD

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Christine M. Seroogy, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Christine M. Seroogy, MD, earned her medical degree from the University of Minnesota and completed her residency at the Harvard University Children's Hospital in Boston, Massachusetts.


Pediatric Allergy, Asthma and Immunology

UW Health Clinics

American Family Children's Hospital
(608) 263-6420 | (800) 323-8942 | Map

Hospital Affiliation(s)

American Family Children's Hospital (primary)
UnityPoint Health - Meriter (secondary)

UW School of Medicine and Public Health

Department of Pediatrics

Professional Certifications and Education

Board Certification Allergy & Immunology
Fellowship University of California San Francisco, San Francisco, CA
Residency Harvard University, Children's Hospital, Boston, MA
Internship University of California, San Diego Medical Center, San Diego, CA
Medical School University of Minnesota School of Medicine, Minneapolis, MN


Best Doctors® in America 2014

Best Doctors® in America 2013

Best Doctors® in America 2011

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Programs & Conditions

  • Immunodeficiency Disorders
PubMed Articles
Sieren S Grow M GoodSmith M Spicer G Deline J Zhao Q Lindstrom MJ Harris AB Rohan AM Seroogy CM . Cross-Sectional Survey on Newborn Screening in Wisconsin Amish and Mennonite Communities. J Community Health. 2016 Apr;41(2):282-8
[PubMed ID: 26433724]
Simhadri VR Mariano JL Zenarruzabeitia O Seroogy CM Holland SM Kuehn HS Rosenzweig SD Borrego F . Intact IL-12 signaling is necessary for the generation of human natural killer cells with enhanced effector function after restimulation. J Allergy Clin Immunol. 2014 Nov;134(5):1190-3.e1
[PubMed ID: 25065718]
Kuehn HS Ouyang W Lo B Deenick EK Niemela JE Avery DT Schickel JN Tran DQ Stoddard J Zhang Y Frucht DM Dumitriu B Scheinberg P Folio LR Frein CA Price S Koh C Heller T Seroogy CM Huttenlocher A Rao VK Su HC Kleiner D Notarangelo LD Rampertaap Y Olivier KN McElwee J Hughes J Pittaluga S Oliveira JB Meffre E Fleisher TA Holland SM Lenardo MJ Tangye SG Uzel G . Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4. Science. 2014 Sep 26;345(6204):1623-7
[PubMed ID: 25213377]
Kwan A Abraham RS Currier R Brower A Andruszewski K Abbott JK Baker M Ballow M Bartoshesky LE Bonilla FA Brokopp C Brooks E Caggana M Celestin J Church JA Comeau AM Connelly JA Cowan MJ Cunningham-Rundles C Dasu T Dave N De La Morena MT Duffner U Fong CT Forbes L Freedenberg D Gelfand EW Hale JE Hanson IC Hay BN Hu D Infante A Johnson D Kapoor N Kay DM Kohn DB Lee R Lehman H Lin Z Lorey F Abdel-Mageed A Manning A McGhee S Moore TB Naides SJ Notarangelo LD Orange JS Pai SY Porteus M Rodriguez R Romberg N Routes J Ruehle M Rubenstein A Saavedra-Matiz CA Scott G Scott PM Secord E Seroogy C Shearer WT Siegel S Silvers SK Stiehm ER Sugerman RW Sullivan JL Tanksley S Tierce ML 4th Verbsky J Vogel B Walker R Walkovich K Walter JE Wasserman RL Watson MS Weinberg GA Weiner LB Wood H Yates AB Puck JM Bonagura VR . Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States. JAMA. 2014 Aug 20;312(7):729-38
[PubMed ID: 25138334]
Wilson MR Naccache SN Samayoa E Biagtan M Bashir H Yu G Salamat SM Somasekar S Federman S Miller S Sokolic R Garabedian E Candotti F Buckley RH Reed KD Meyer TL Seroogy CM Galloway R Henderson SL Gern JE DeRisi JL Chiu CY . Actionable diagnosis of neuroleptospirosis by next-generation sequencing. N Engl J Med. 2014 Jun 19;370(25):2408-17
[PubMed ID: 24896819]
Giampietro PF Baker MW Basehore MJ Jones JR Seroogy CM . Novel mutation in TP63 associated with ectrodactyly ectodermal dysplasia and clefting syndrome and T cell lymphopenia. Am J Med Genet A. 2013 Jun;161A(6):1432-5
[PubMed ID: 23613309]
Singh AM Dahlberg P Burmeister K Evans MD Gangnon R Roberg KA Tisler C Dasilva D Pappas T Salazar L Lemanske RF Jr Gern JE Seroogy CM . Inhaled corticosteroid use is associated with increased circulating T regulatory cells in children with asthma. Clin Mol Allergy. 2013 Jan 25;11(1):1
[PubMed ID: 23347774]
Russ AJ Wentworth L Xu K Rakhmilevich A Seroogy CM Sondel PM Suresh M Cho CS . Suppression of T-cell expansion by melanoma is exerted on resting cells. Ann Surg Oncol. 2011 Dec;18(13):3848-57
[PubMed ID: 21465311]
Wernimont SA Simonson WT Greer PA Seroogy CM Huttenlocher A . Calpain 4 is not necessary for LFA-1-mediated function in CD4+ T cells. PLoS One. 2010 May 7;5(5):e10513
[PubMed ID: 20479866]
Schartner JM Simonson WT Wernimont SA Nettenstrom LM Huttenlocher A Seroogy CM . Gene related to anergy in lymphocytes (GRAIL) expression in CD4+ T cells impairs actin cytoskeletal organization during T cell/antigen-presenting cell interactions. J Biol Chem. 2009 Dec 11;284(50):34674-81
[PubMed ID: 19833735]
MacKenzie DA Seroogy CM . Sustained expression of GRAIL during hematopoiesis results in dysregulated differentiation. Acta Haematol. 2009;122(4):230-7
[PubMed ID: 19887782]
Shamim M Nanjappa SG Singh A Plisch EH LeBlanc SE Walent J Svaren J Seroogy C Suresh M . Cbl-b regulates antigen-induced TCR down-regulation and IFN-gamma production by effector CD8 T cells without affecting functional avidity. J Immunol. 2007 Dec 1;179(11):7233-43
[PubMed ID: 18025165]
Jartti T Burmeister KA Seroogy CM Jennens-Clough ML Tisler CJ Salazar LP Dasilva DF Evans MD Vrtis RF Wallace PK Ruiz-Perez B Gangnon RE Lemanske RF Jr Gern JE . Association between CD4(+)CD25(high) T cells and atopy in children. J Allergy Clin Immunol. 2007 Jul;120(1):177-83
[PubMed ID: 17433828]
MacKenzie DA Schartner J Lin J Timmel A Jennens-Clough M Fathman CG Seroogy CM . GRAIL is up-regulated in CD4+ CD25+ T regulatory cells and is sufficient for conversion of T cells to a regulatory phenotype. J Biol Chem. 2007 Mar 30;282(13):9696-702
[PubMed ID: 17259178]
Karman J Chu HH Co DO Seroogy CM Sandor M Fabry Z . Dendritic cells amplify T cell-mediated immune responses in the central nervous system. J Immunol. 2006 Dec 1;177(11):7750-60
[PubMed ID: 17114446]
Seroogy CM Gern JE . The role of T regulatory cells in asthma. J Allergy Clin Immunol. 2005 Nov;116(5):996-9
[PubMed ID: 16275366]
Seroogy CM Fathman CG . T-cell anergy: from phenotype to genotype and back. Immunol Res. 2003;28(3):255-64
[PubMed ID: 14713718]