American Family Children's Hospital
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Barbara E.K. Klein, MD, MPH close
Barbara E.K. Klein, MD, MPH


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Barbara E.K. Klein, MD, MPH Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Klein is co-director of the Beaver Dam Eye Study, which collects information on the prevalence and incidence of age-related cataract, macular degeneration,and diabetic retinopathy, which are all common eye diseases in an aging population. The study also has examined other aging issues, such as overall health, quality-of-life and environmental and medicinal exposures.

Specialties

Eye Care Services (Ophthalmology)

UW Health Clinics

University Station Clinic
(608) 263-7171 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital (primary)
Veterans Hospital - Wm. S. Middleton Memorial (secondary)

UW School of Medicine and Public Health

Department of Ophthalmology and Visual Sciences

Professional Certifications and Education

Board Certification Ophthalmology
Preventive Medicine
Fellowship University of Wisconsin Hospital and Clinics, Madison, WI
Residency University of Wisconsin Hospital and Clinics, Madison, WI
Internship Bellevue Hospital, New York, NY
New York University Medical Center, New York, NY
Medical School New York University, New York, NY, 1969

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Programs & Conditions

PubMed Articles
Roshandel D Klein R Klein BE Wolffenbuttel BH van der Klauw MM van Vliet-Ostaptchouk JV Atzmon G Ben-Avraham D Crandall JP Barzilai N Bull SB Canty AJ Hosseini SM Hiraki LT Maynard J Sell DR Monnier VM Cleary PA Braffett BH Paterson AD . New Locus for Skin Intrinsic Fluorescence in Type 1 Diabetes Also Associated With Blood and Skin Glycated Proteins. Diabetes. 2016 Jul;65(7):2060-71
[PubMed ID: 27207532]
Howard KP Chandler CS Huang Y Klein BE Lee KE Meuer SM Danis RP Danforth LG Gangnon RE Klein R . Variability in Spectral-Domain Optical Coherence Tomography over 4 Weeks by Age. Ophthalmic Epidemiol. 2016 Jun;23(3):193-201
[PubMed ID: 27128499]
Fisher DE Klein BE Wong TY Rotter JI Li X Shrager S Burke GL Klein R Cotch MF . Incidence of Age-Related Macular Degeneration in a Multi-Ethnic United States Population: The Multi-Ethnic Study of Atherosclerosis. Ophthalmology. 2016 Jun;123(6):1297-308
[PubMed ID: 26896123]
Gori M Gupta DK Claggett B Selvin E Folsom AR Matsushita K Bello NA Cheng S Shah A Skali H Vardeny O Ni H Ballantyne CM Astor BC Klein BE Aguilar D Solomon SD . Natriuretic Peptide and High-Sensitivity Troponin for Cardiovascular Risk Prediction in Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study. Diabetes Care. 2016 May;39(5):677-85
[PubMed ID: 26740635]
Klein R Klein BE . Body Fat Distribution and Diabetic Retinopathy in People With Type 2 Diabetes. JAMA. 2016 Apr 26;315(16):1778-9
[PubMed ID: 27115379]
Wichmann MA Cruickshanks KJ Carlsson CM Chappell R Fischer ME Klein BE Klein R Schubert CR . NSAID Use and Incident Cognitive Impairment in a Population-based Cohort. Alzheimer Dis Assoc Disord. 2016 Apr-Jun;30(2):105-12
[PubMed ID: 26079710]
Porta M Toppila I Sandholm N Hosseini SM Forsblom C Hietala K Borio L Harjutsalo V Klein BE Klein R Paterson AD Groop PH . Variation in SLC19A3 and Protection From Microvascular Damage in Type 1 Diabetes. Diabetes. 2016 Apr;65(4):1022-30
[PubMed ID: 26718501]
Sahli MW Mares JA Meyers KJ Klein R Brady WE Klein BE Ochs-Balcom HM Donahue RP Millen AE . Dietary Intake of Lutein and Diabetic Retinopathy in the Atherosclerosis Risk in Communities Study (ARIC). Ophthalmic Epidemiol. 2016 Apr;23(2):99-108
[PubMed ID: 26949989]
Fan Q Verhoeven VJ Wojciechowski R Barathi VA Hysi PG Guggenheim JA Höhn R Vitart V Khawaja AP Yamashiro K Hosseini SM Lehtimäki T Lu Y Haller T Xie J Delcourt C Pirastu M Wedenoja J Gharahkhani P Venturini C Miyake M Hewitt AW Guo X Mazur J Huffman JE Williams KM Polasek O Campbell H Rudan I Vatavuk Z Wilson JF Joshi PK McMahon G St Pourcain B Evans DM Simpson CL Schwantes-An TH Igo RP Mirshahi A Cougnard-Gregoire A Bellenguez C Blettner M Raitakari O Kähönen M Seppala I Zeller T Meitinger T Ried JS Gieger C Portas L van Leeuwen EM Amin N Uitterlinden AG Rivadeneira F Hofman A Vingerling JR Wang YX Wang X Tai-Hui Boh E Ikram MK Sabanayagam C Gupta P Tan V Zhou L Ho CE Lim W Beuerman RW Siantar R Tai ES Vithana E Mihailov E Khor CC Hayward C Luben RN Foster PJ Klein BE Klein R Wong HS Mitchell P Metspalu A Aung T Young TL He M Pärssinen O van Duijn CM Jin Wang J Williams C Jonas JB Teo YY Mackey DA Oexle K Yoshimura N Paterson AD Pfeiffer N Wong TY Baird PN Stambolian D Wilson JE Cheng CY Hammond CJ Klaver CC Saw SM Rahi JS Korobelnik JF Kemp JP Timpson NJ Smith GD Craig JE Burdon KP Fogarty RD Iyengar SK Chew E Janmahasatian S Martin NG MacGregor S Xu L Schache M Nangia V Panda-Jonas S Wright AF Fondran JR Lass JH Feng S Zhao JH Khaw KT Wareham NJ Rantanen T Kaprio J Pang CP Chen LJ Tam PO Jhanji V Young AL Döring A Raffel LJ Cotch MF Li X Yip SP Yap MK Biino G Vaccargiu S Fossarello M Fleck B Yazar S Tideman JW Tedja M Deangelis MM Morrison M Farrer L Zhou X Chen W Mizuki N Meguro A Mäkelä KM . Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. Nat Commun. 2016 Mar 29;7:11008
[PubMed ID: 27020472]
Tan AG Kifley A Mitchell P Rochtchina E Flood VM Cumming RG Jun G Holliday EG Scott RJ Teo YY Klein BE Cheng CY Iyengar SK Wang JJ . Associations Between Methylenetetrahydrofolate Reductase Polymorphisms, Serum Homocysteine Levels, and Incident Cortical Cataract. JAMA Ophthalmol. 2016 Mar 17;
[PubMed ID: 26986182]
Schubert CR Fischer ME Pinto AA Klein BE Klein R Tweed TS Cruickshanks KJ . Sensory Impairments and Risk of Mortality in Older Adults. J Gerontol A Biol Sci Med Sci. 2016 Mar 4;
[PubMed ID: 26946102]
Chew M Xie J Klein R Klein B Cotch MF Redline S Wong TY Cheung N . Sleep apnea and retinal signs in cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis. Sleep Breath. 2016 Mar;20(1):15-23
[PubMed ID: 25903075]
Dauer LT Ainsbury EA Dynlacht J Hoel D Klein BE Mayer D Prescott CR Thornton RH Vano E Woloschak GE Flannery CM Goldstein LE Hamada N Tran PK Grissom MP Blakely EA . Status of NCRP Scientific Committee 1-23 Commentary on Guidance on Radiation Dose Limits for the Lens of the Eye. Health Phys. 2016 Feb;110(2):182-4
[PubMed ID: 26717175]
Fritsche LG Igl W Bailey JN Grassmann F Sengupta S Bragg-Gresham JL Burdon KP Hebbring SJ Wen C Gorski M Kim IK Cho D Zack D Souied E Scholl HP Bala E Lee KE Hunter DJ Sardell RJ Mitchell P Merriam JE Cipriani V Hoffman JD Schick T Lechanteur YT Guymer RH Johnson MP Jiang Y Stanton CM Buitendijk GH Zhan X Kwong AM Boleda A Brooks M Gieser L Ratnapriya R Branham KE Foerster JR Heckenlively JR Othman MI Vote BJ Liang HH Souzeau E McAllister IL Isaacs T Hall J Lake S Mackey DA Constable IJ Craig JE Kitchner TE Yang Z Su Z Luo H Chen D Ouyang H Flagg K Lin D Mao G Ferreyra H Stark K von Strachwitz CN Wolf A Brandl C Rudolph G Olden M Morrison MA Morgan DJ Schu M Ahn J Silvestri G Tsironi EE Park KH Farrer LA Orlin A Brucker A Li M Curcio CA Mohand-Saïd S Sahel JA Audo I Benchaboune M Cree AJ Rennie CA Goverdhan SV Grunin M Hagbi-Levi S Campochiaro P Katsanis N Holz FG Blond F Blanché H Deleuze JF Igo RP Jr Truitt B Peachey NS Meuer SM Myers CE Moore EL Klein R Hauser MA Postel EA Courtenay MD Schwartz SG Kovach JL Scott WK Liew G Tan AG Gopinath B Merriam JC Smith RT Khan JC Shahid H Moore AT McGrath JA Laux R Brantley MA Jr Agarwal A Ersoy L Caramoy A Langmann T Saksens NT de Jong EK Hoyng CB Cain MS Richardson AJ Martin TM Blangero J Weeks DE Dhillon B van Duijn CM Doheny KF Romm J Klaver CC Hayward C Gorin MB Klein ML Baird PN den Hollander AI Fauser S Yates JR Allikmets R Wang JJ Schaumberg DA Klein BE Hagstrom SA Chowers I Lotery AJ Léveillard T Zhang K Brilliant MH Hewitt AW Swaroop A Chew EY Pericak-Vance MA DeAngelis M Stambolian D Haines JL Iyengar SK Weber BH Abecasis GR Heid IM . A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. Nat Genet. 2016 Feb;48(2):134-43
[PubMed ID: 26691988]
Meuer SM Klein BE Myers CE Klein R . Reply: To PMID 25556116. Ophthalmology. 2015 Dec;122(12):e72
[PubMed ID: 26592679]
Sabanayagam C Lye WK Klein R Klein BE Cotch MF Wang JJ Mitchell P Shaw JE Selvin E Sharrett AR Wong TY . Retinal microvascular calibre and risk of diabetes mellitus: a systematic review and participant-level meta-analysis. Diabetologia. 2015 Nov;58(11):2476-85
[PubMed ID: 26232097]
Tremblay KL Pinto A Fischer ME Klein BE Klein R Levy S Tweed TS Cruickshanks KJ . Self-Reported Hearing Difficulties Among Adults With Normal Audiograms: The Beaver Dam Offspring Study. Ear Hear. 2015 Nov-Dec;36(6):e290-9
[PubMed ID: 26164105]
Chacko BG Edwards MS Sharrett AR Qureshi WT Klein BE Klein R Herrington DM Soliman EZ . Microvasculature and incident atrioventricular conduction abnormalities in the Multi-Ethnic Study of Atherosclerosis (MESA). Vasc Med. 2015 Oct;20(5):417-23
[PubMed ID: 25999364]
Kong J Klein BE Klein R Wahba G . Backward multiple imputation estimation of the conditional lifetime expectancy function with application to censored human longevity data. Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):12069-74
[PubMed ID: 26371300]
Schubert CR Cruickshanks KJ Fischer ME Klein BE Klein R Pinto AA . Inflammatory and vascular markers and olfactory impairment in older adults. Age Ageing. 2015 Sep;44(5):878-82
[PubMed ID: 26082178]