American Family Children's Hospital
Barbara E.K. Klein, MD, MPH close
Barbara E.K. Klein, MD, MPH

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Barbara E.K. Klein, MD, MPH Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Klein is co-director of the Beaver Dam Eye Study, which collects information on the prevalence and incidence of age-related cataract, macular degeneration,and diabetic retinopathy, which are all common eye diseases in an aging population. The study also has examined other aging issues, such as overall health, quality-of-life and environmental and medicinal exposures.


Eye Care Services (Ophthalmology)

UW Health Clinics

University Station Clinic
(608) 263-7171 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital (primary)
Veterans Hospital - Wm. S. Middleton Memorial (secondary)

UW School of Medicine and Public Health

Department of Ophthalmology and Visual Sciences

Professional Certifications and Education

Board Certification Ophthalmology
Preventive Medicine
Fellowship University of Wisconsin Hospital and Clinics, Madison, WI
Residency University of Wisconsin Hospital and Clinics, Madison, WI
Internship Bellevue Hospital, New York, NY
New York University Medical Center, New York, NY
Medical School New York University, New York, NY, 1969

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Programs & Conditions

PubMed Articles
Chen Y Nondahl DM Schubert CR Klein BE Klein R Cruickshanks KJ . The Relation between Sleep Disruption and Cataract in a Large Population-Based Study. Ophthalmic Epidemiol. 2017 Jan 31;:1-5
[PubMed ID: 28139160]
Klein BE Johnson CA Meuer SM Lee K Wahle A Lee KE Kulkarni A Sonka M Abràmoff MD Klein R . Nerve Fiber Layer Thickness and Characteristics Associated with Glaucoma in Community Living Older Adults: Prelude to a Screening Trial? Ophthalmic Epidemiol. 2016 Dec 29;:1-7
[PubMed ID: 28032805]
Schubert CR Fischer ME Pinto AA Klein BE Klein R Cruickshanks KJ . Odor detection thresholds in a population of older adults. Laryngoscope. 2016 Dec 21;
[PubMed ID: 28000220]
Fischer ME Cruickshanks KJ Nondahl DM Klein BE Klein R Pankow JS Tweed TS Dalton DS Paulsen AJ . Dichotic Digits Test Performance Across the Ages: Results From Two Large Epidemiologic Cohort Studies. Ear Hear. 2016 Dec 7;
[PubMed ID: 27941404]
Seidelmann SB Claggett B Bravo PE Gupta A Farhad H Klein BE Klein R Di Carli M Solomon SD . Retinal Vessel Calibers in Predicting Long-Term Cardiovascular Outcomes: The Atherosclerosis Risk in Communities Study. Circulation. 2016 Nov 1;134(18):1328-1338
[PubMed ID: 27682886]
Ryan CM Klein BE Lee KE Cruickshanks KJ Klein R . Associations between recent severe hypoglycemia, retinal vessel diameters, and cognition in adults with type 1 diabetes. J Diabetes Complications. 2016 Nov - Dec;30(8):1513-1518
[PubMed ID: 27601058]
O'Neal WT Lee KE Soliman EZ Klein R Klein BE . Predictors of electrocardiographic abnormalities in type 1 Diabetes: the Wisconsin Epidemiologic Study of Diabetic Retinopathy. J Endocrinol Invest. 2016 Oct 20;
[PubMed ID: 27766550]
Yip W Tham YC Hsu W Lee ML Klein R Klein B Ikram MK Wong TY Cheung CY . Comparison of Common Retinal Vessel Caliber Measurement Software and a Conversion Algorithm. Transl Vis Sci Technol. 2016 Oct 12;5(5):11
[PubMed ID: 27752402]
Fischer ME Cruickshanks KJ Schubert CR Pinto AA Carlsson CM Klein BE Klein R Tweed TS . Age-Related Sensory Impairments and Risk of Cognitive Impairment. J Am Geriatr Soc. 2016 Oct;64(10):1981-1987
[PubMed ID: 27611845]
Millen AE Sahli MW Nie J LaMonte MJ Lutsey PL Klein BE Mares JA Meyers KJ Andrews CA Klein R . Adequate vitamin D status is associated with the reduced odds of prevalent diabetic retinopathy in African Americans and Caucasians. Cardiovasc Diabetol. 2016 Sep 1;15(1):128
[PubMed ID: 27586865]
Lin GM Redline S Klein R Colangelo LA Cotch MF Wong TY Klein BE Patel SR Shea SJ Liu K . Sex-Specific Association of Obstructive Sleep Apnea With Retinal Microvascular Signs: The Multi-Ethnic Study of Atherosclerosis. J Am Heart Assoc. 2016 Jul 22;5(7)
[PubMed ID: 27451457]
Chen F Duggal P Klein BE Lee KE Truitt B Klein R Iyengar SK Klein AP . Variation in PTCHD2, CRISP3, NAP1L4, FSCB, and AP3B2 associated with spherical equivalent. Mol Vis. 2016 Jul 14;22:783-96
[PubMed ID: 27440996]
Roshandel D Klein R Klein BE Wolffenbuttel BH van der Klauw MM van Vliet-Ostaptchouk JV Atzmon G Ben-Avraham D Crandall JP Barzilai N Bull SB Canty AJ Hosseini SM Hiraki LT Maynard J Sell DR Monnier VM Cleary PA Braffett BH Paterson AD . New Locus for Skin Intrinsic Fluorescence in Type 1 Diabetes Also Associated With Blood and Skin Glycated Proteins. Diabetes. 2016 Jul;65(7):2060-71
[PubMed ID: 27207532]
Howard KP Chandler CS Huang Y Klein BE Lee KE Meuer SM Danis RP Danforth LG Gangnon RE Klein R . Variability in Spectral-Domain Optical Coherence Tomography over 4 Weeks by Age. Ophthalmic Epidemiol. 2016 Jun;23(3):193-201
[PubMed ID: 27128499]
Fisher DE Klein BE Wong TY Rotter JI Li X Shrager S Burke GL Klein R Cotch MF . Incidence of Age-Related Macular Degeneration in a Multi-Ethnic United States Population: The Multi-Ethnic Study of Atherosclerosis. Ophthalmology. 2016 Jun;123(6):1297-308
[PubMed ID: 26896123]
Gori M Gupta DK Claggett B Selvin E Folsom AR Matsushita K Bello NA Cheng S Shah A Skali H Vardeny O Ni H Ballantyne CM Astor BC Klein BE Aguilar D Solomon SD . Natriuretic Peptide and High-Sensitivity Troponin for Cardiovascular Risk Prediction in Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study. Diabetes Care. 2016 May;39(5):677-85
[PubMed ID: 26740635]
Klein R Klein BE . Body Fat Distribution and Diabetic Retinopathy in People With Type 2 Diabetes. JAMA. 2016 Apr 26;315(16):1778-9
[PubMed ID: 27115379]
Wichmann MA Cruickshanks KJ Carlsson CM Chappell R Fischer ME Klein BE Klein R Schubert CR . NSAID Use and Incident Cognitive Impairment in a Population-based Cohort. Alzheimer Dis Assoc Disord. 2016 Apr-Jun;30(2):105-12
[PubMed ID: 26079710]
Porta M Toppila I Sandholm N Hosseini SM Forsblom C Hietala K Borio L Harjutsalo V Klein BE Klein R Paterson AD Groop PH . Variation in SLC19A3 and Protection From Microvascular Damage in Type 1 Diabetes. Diabetes. 2016 Apr;65(4):1022-30
[PubMed ID: 26718501]
Fan Q Verhoeven VJ Wojciechowski R Barathi VA Hysi PG Guggenheim JA Höhn R Vitart V Khawaja AP Yamashiro K Hosseini SM Lehtimäki T Lu Y Haller T Xie J Delcourt C Pirastu M Wedenoja J Gharahkhani P Venturini C Miyake M Hewitt AW Guo X Mazur J Huffman JE Williams KM Polasek O Campbell H Rudan I Vatavuk Z Wilson JF Joshi PK McMahon G St Pourcain B Evans DM Simpson CL Schwantes-An TH Igo RP Mirshahi A Cougnard-Gregoire A Bellenguez C Blettner M Raitakari O Kähönen M Seppala I Zeller T Meitinger T Ried JS Gieger C Portas L van Leeuwen EM Amin N Uitterlinden AG Rivadeneira F Hofman A Vingerling JR Wang YX Wang X Tai-Hui Boh E Ikram MK Sabanayagam C Gupta P Tan V Zhou L Ho CE Lim W Beuerman RW Siantar R Tai ES Vithana E Mihailov E Khor CC Hayward C Luben RN Foster PJ Klein BE Klein R Wong HS Mitchell P Metspalu A Aung T Young TL He M Pärssinen O van Duijn CM Jin Wang J Williams C Jonas JB Teo YY Mackey DA Oexle K Yoshimura N Paterson AD Pfeiffer N Wong TY Baird PN Stambolian D Wilson JE Cheng CY Hammond CJ Klaver CC Saw SM Rahi JS Korobelnik JF Kemp JP Timpson NJ Smith GD Craig JE Burdon KP Fogarty RD Iyengar SK Chew E Janmahasatian S Martin NG MacGregor S Xu L Schache M Nangia V Panda-Jonas S Wright AF Fondran JR Lass JH Feng S Zhao JH Khaw KT Wareham NJ Rantanen T Kaprio J Pang CP Chen LJ Tam PO Jhanji V Young AL Döring A Raffel LJ Cotch MF Li X Yip SP Yap MK Biino G Vaccargiu S Fossarello M Fleck B Yazar S Tideman JW Tedja M Deangelis MM Morrison M Farrer L Zhou X Chen W Mizuki N Meguro A Mäkelä KM . Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. Nat Commun. 2016 Mar 29;7:11008
[PubMed ID: 27020472]